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System and method for processing and detecting nucleic acids

  • US 9,441,219 B2
  • Filed: 05/05/2015
  • Issued: 09/13/2016
  • Est. Priority Date: 02/13/2012
  • Status: Active Grant
First Claim
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1. A molecular diagnostic module configured to process a biological sample and separate a nucleic acid volume from the biological sample, the molecular diagnostic module comprising:

  • a valve actuation subsystem comprising a set of pins;

    an actuator configured to provide relative displacement between a cartridge, for receiving the biological sample, and the valve actuation subsystem, thereby providing an active configuration, wherein in the active configuration the cartridge is disposed proximal the set of pins, and wherein the cartridge comprises a pathway; and

    a cam module configured to displace a subset of the set of pins in the active configuration to define a pathway, that facilitates separation of the nucleic acid volume from the biological sample, in the cartridge, wherein in the active configuration the subset of the set of pins cooperatively defines and occludes the pathway of the cartridge.

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