Single coil magnetic induction tomographic imaging

• US 9,442,088 B2
• Filed: 02/27/2014
• Issued: 09/13/2016
• Est. Priority Date: 02/27/2014
• Status: Active Grant

• Current Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Feldkamp, Joseph R., Sullivan, Shawn Jeffery
• Primary Examiner(s): Koval, Melissa
• Assistant Examiner(s): PATEL, RISHI R
• Application Number:
  US14/191,913
• Publication Number:
  US 20150241372A1
• Time in Patent Office: 929 Days
• Field of Search: 324300-322
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0522 Magnetic induction tomography
• CPC Class Codes: G01N 27/025 a current being generated within the material by induction

Abstract

Systems, methods, and apparatus for magnetic induction tomography imaging of specimens, such as human tissue specimens, using a single coil are provided. A plurality of coil property measurements can be obtained using the single coil at a plurality of discrete locations relative to the specimen. The single coil can be designed to be relatively easy to be placed in many different positions/orientations relative to the specimen. A three-dimensional electromagnetic property map, such as a three-dimensional conductivity map or a three-dimensional permittivity map, can be generated from the plurality of coil property measurements obtained using the single coil by accessing a model correlating coil property measurements obtained by the single coil with an electromagnetic property distribution of the specimen.

Claims

1. A method for magnetic induction tomography imaging, the method comprising:

accessing, by one or more computing devices, a plurality of coil property measurements obtained for a specimen associated with a single coil coupled to and energized with radio frequency energy from an RF energy source, each of the plurality of coil property measurements obtained with the single coil at one of a plurality of discrete locations relative to a specimen, each coil property measurement comprising a detected coil property of the single coil coupled to and energized with radiofrequency energy from an RF energy source;

associating, by the one or more computing devices, coil position data with each of the plurality of coil property measurements, the coil position data indicative of the position and orientation of the single coil relative to the specimen for each coil property measurement;

accessing, by the one or more computing devices, a model defining a relationship between coil property measurements obtained by the single coil at a plurality of different positions relative to the specimen and an electromagnetic property of the specimen; and

generating, by the one or more computing devices, a three-dimensional electromagnetic property map of the specimen using the model based at least in part on the plurality of coil property measurements and the coil position data associated with each coil property measurement.

2. The method of claim 1, wherein each of the plurality of coil property measurements comprises a coil loss measurement indicative of a change in impedance of the single coil resulting from eddy currents induced in the specimen when the single coil is placed adjacent to the specimen and energized with radiofrequency energy.

3. The method of claim 1, wherein the plurality of coil property measurements are obtained while the single coil is mounted to a translation device, the translation device configured to move the single coil to the plurality of discrete locations.

4. The method of claim 3, wherein the coil position data is obtained from the translation device.

5. The method of claim 1, wherein the coil position data is determined based at least in part on data generated by one or more sensors.

6. The method of claim 1, wherein the coil position data is determined based at least in part on images captured of a graphic located on a surface of a coil device having the single coil.

7. The method of claim 1, wherein the model correlates a change in impedance of the single coil with a plurality of parameters, the plurality of parameters comprising at least a conductivity distribution of the specimen and a position and an orientation of the single coil relative to the specimen.

8. The method of claim 1, wherein the electromagnetic property map is a three-dimensional conductivity map of the specimen.

9. The method of claim 1, wherein the three-dimensional electromagnetic property map is generated using the model by discretizing the specimen into a finite element mesh or grid.

10. The method of claim 1, wherein the plurality of coil property measurements comprises a plurality of data sets of coil property measurements, each of the plurality of data sets obtained from a different single coil at a different time.

21. The method of claim 1, wherein the specimen comprises a tissue specimen.

22. The method of claim 21, wherein the tissue specimen comprises a human tissue specimen.

23. The method of claim 1, wherein two or more of the plurality of coil property measurements are associated with a different orientation of the single coil relative to the specimen.

24. The method of claim 1, wherein the plurality of coil property measurements comprises a first coil property measurement obtained with the single coil at a first orientation relative to the specimen and a second coil property measurement obtained with the single coil at a second orientation relative to the specimen, the first orientation being different from the second orientation.

11. A system for magnetic induction tomography imaging of a specimen, the system comprising:

a coil device having a single coil coupled to an RF energy source, the single coil comprising a plurality of concentric conductive loops, each of the plurality of concentric conductive loops having a different radius, the single coil configured to obtain a coil loss measurement;

a translation device configured to position the single coil relative to the specimen at a plurality of discrete locations relative to the specimen;

a computing system comprising one or more processors and one or more memory devices, the one or more memory devices storing computer-readable instructions that when executed by the one or more processors cause the one or more processors to perform operations, the operations comprising;

accessing a plurality of coil loss measurements associated with the single coil, each of the plurality of coil loss measurements obtained using the single coil coupled to an energy with radio frequency energy from the RF energy source, each of the plurality of coil property measurements obtained at one of the plurality of discrete locations relative to a specimen, each coil loss measurement comprising a detected coil loss of the single coil coupled to and energized with radiofrequency energy from an RF energy source;

associating coil position data with each of the plurality of coil loss measurements, the coil position data indicative of the position and orientation of the single coil relative to the specimen for each coil loss measurement;

accessing a model defining a relationship between coil property measurements obtained by the single coil at a plurality of different positions relative to the specimen and a conductivity of the specimen; and

generating a three-dimensional conductivity map of the specimen using the model based at least in part on the plurality of coil loss measurements and the coil position data associated with each coil property measurement.

12. The system of claim 11, wherein the coil loss measurement is indicative of a change in impedance of the single coil resulting from eddy currents induced in the specimen when the single coil is placed adjacent to the specimen and energized with radiofrequency energy.

13. The system of claim 11, wherein the coil position data is determined based at least in part on data generated by one or more sensors.

14. The system of claim 11, wherein the coil position data is determined based at least in part on images captured of a graphic located on a surface of a coil device having the single coil.

15. The system of claim 11, wherein the model correlates a change in impedance of the single coil with a plurality of parameters, the plurality of parameters comprising at least a conductivity distribution of the specimen, a position and an orientation of the single coil relative to the specimen, and a radius of each of the plurality of concentric conductive loops in the single coil.

16. The system of claim 11, wherein the three-dimensional conductivity map is generated using the model by discretizing the specimen into a finite element mesh.

17. The system of claim 11, wherein the plurality of coil property measurements comprises a plurality of data sets of coil property measurements, each of the plurality of data sets obtained from a different single coil at a different time.

18. One or more tangible, non-transitory computer-readable media storing computer-readable instructions that when executed by one or more processors cause the one or more processors to perform operations for magnetic induction tomography of a human tissue specimen, the operations comprising:

accessing a plurality of coil loss measurements obtained for the human tissue specimen using a single coil coupled to and energized with radio frequency energy from and RF energy source, each of the plurality of coil loss measurements obtained using the single coil at one of a plurality of discrete locations relative to the human tissue specimen, each coil loss measurement indicative of a change in impedance of the single coil resulting from eddy currents induced in the human tissue specimen when the single coil coupled to and energized with radiofrequency energy;

associating coil position data with each of the plurality of coil loss measurements, the coil position data indicative of the position and orientation of the single coil relative to the human tissue specimen for each coil property measurement;

accessing a model defining a relationship between coil loss measurements obtained by the single coil at a plurality of positions relative to the specimen and a conductivity of the human tissue-specimen; and

generating a three-dimensional conductivity map of the human tissue specimen using the model based at least in part on the plurality of coil loss measurements and the coil position data associated with each coil loss measurement.

19. The one or more tangible, non-transitory computer-readable media of claim 18, wherein the model correlates a change in impedance of the single coil with a plurality of parameters, the plurality of parameters comprising at least the conductivity of the human tissue specimen and a position and an orientation of the single coil relative to the specimen.

20. The one or more tangible, non-transitory computer-readable media of claim 18, wherein the operation of generating a three-dimensional conductivity map of the specimen using the model based at least in part on the plurality of coil loss measurements and the coil position data associated with each coil loss measurement comprises discretizing the human tissue specimen into a finite element mesh.