Optical coherence photoacoustic microscopy
First Claim
1. An optical coherence photoacoustic microscope comprising:
- a light source that outputs light of a single center wavelength;
a scanner that scans the output light of the single center wavelength across a sample by moving at least one of the sample and the light relative to the other of the sample and the light;
a detector that receives reflected light from the sample in response to the scanned light;
a transducer positioned to detect photoacoustic waves induced in the sample by the scanned light; and
an image processing module that receives output from the transducer and the detector and that generates a photoacoustic microscopy (PAM) image and an optical coherence tomography (OCT) image based on the received output.
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Accused Products
Abstract
A system and method for providing an optical coherence photoacoustic (OC-PAM) microscopy. An OC-PAM microscope includes a light source that outputs light, a scanner, a detector, a transducer, and an image processing module. The scanner receives the light and scans the light across a sample. The detector receives reflected light from the sample in response to the scanned light. The transducer detects photoacoustic waves induced in the sample by the scanned light. The image processing module receives output from the detector and the transducer and generates a photoacoustic microscopy (PAM) image and an optical coherence tomography (OCT) image based on the received output from the detector and the transducer. The PAM and OCT image data may be fused to form a single, OC-PAM image. Additionally, a series of PAM images and OCT images, respectively, may be combined to generate three-dimensional PAM and OCT images, respectively.
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Citations
30 Claims
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1. An optical coherence photoacoustic microscope comprising:
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a light source that outputs light of a single center wavelength; a scanner that scans the output light of the single center wavelength across a sample by moving at least one of the sample and the light relative to the other of the sample and the light; a detector that receives reflected light from the sample in response to the scanned light; a transducer positioned to detect photoacoustic waves induced in the sample by the scanned light; and an image processing module that receives output from the transducer and the detector and that generates a photoacoustic microscopy (PAM) image and an optical coherence tomography (OCT) image based on the received output. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method for optical coherence photoacoustic microscopy comprising:
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emitting light of a single center wavelength from a light source; scanning the light of the single center wavelength across a sample by moving at least one of the sample and the light relative to the other of the sample and the light; receiving, by a detector, reflected light from the sample in response to the scanned light; detecting, by a transducer, photoacoustic waves induced in the sample by the scanned light; receiving, by an image processing module, output from the transducer and the detector; and generating, by the image processing module, a photoacoustic microscopy (PAM) image and an optical coherence tomography (OCT) image based on the received output. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification