Methods for locating a blood vessel

• US 9,445,766 B1
• Filed: 09/28/2009
• Issued: 09/20/2016
• Est. Priority Date: 07/08/2009
• Status: Active Grant

• Current Assignee: ViOptix, Inc.
• Original Assignee: ViOptix, Inc.
• Inventors: Lash, Robert E., Mao, Jimmy Jian-min
• Primary Examiner(s): Smith, Ruth S
• Application Number:
  US12/568,470
• Time in Patent Office: 2,549 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 1/00013 using optical means
• CPC Class Codes: A61B 17/3403 Needle locating or guiding means guides for suture needles A61B17/0482; guiding or tracking by nuclear magnetic resonance G01R33/285
• CPC Class Codes: A61B 5/00 Measuring for diagnostic purposes radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00; Identification of persons
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/489 Blood vessels
• CPC Class Codes: A61B 5/6847 mounted on an invasive device
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61M 29/00 Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104

Abstract

The present invention relates to methods for differentiating a blood vessel from a nonvascular tissue during a minimally invasive surgery using a device. A device may be any penetration sensor device, such as a dilator sensor device, a hollow needle sensor device, or a trocar sensor device, which penetrates the skin and subcutaneous layers to reach a target location inside the body. The penetration sensor device includes a sensor probe which can make optical measurements to determine various parameters of the tissue at the tip of the sensor probe. These parameters may include an optical signal level returned from tissue contacting the tip of the sensor probe, an oxygen saturation level of the tissue, a total hemoglobin concentration, a blood flow, and a pulse. Based on these parameters, the presence or absence of a blood vessel at the tip of the penetration sensor device can be determined while the device travels towards the target location for surgery.

Claims

1. A method for differentiating a blood vessel from a nonvascular tissue inside a patient'"'"'s body cavity during a surgical procedure, comprising:

transmitting a first light signal through optical fibers in a penetration sensor device comprising a tip, wherein the first light signal is emitted in a first direction ahead of the tip into a tissue;

receiving a second light signal reflected from the tissue ahead of the tip through the optical fibers in the penetration sensor device;

determining an indicator of presence of a blood vessel ahead of the tip of the penetration sensor device based on information from the first light signal and the second light signal;

identifying the tissue as a blood vessel if the indicator for presence of a blood vessel is greater than a threshold,

wherein the penetration sensor device comprises a penetration instrument having a tubular body with a lumen along a longitudinal axis of the tubular body, and a sensor probe, coupled to the penetration instrument, comprising a sensor unit, at a tip of the sensor probe, having emitter and detector sensor openings, optical fibers wherein a first distal end of a first optical fiber of the optical fibers is coupled to the emitter sensor opening and a second distal end of a second optical fiber of the optical fibers is coupled to the detector sensor opening, and a connector which includes proximal ends of the fibers and is configured to couple the penetration sensor device to a system unit.

2. The method of claim 1 wherein the indicator for presence of a blood vessel is determined based on one or combinations of parameters which include a signal level of the second light, a total hemoglobin concentration, an oxygen saturation level, a blood flow, and a pulse.

3. The method of claim 1 wherein the penetration sensor device is a dilator sensor device.

4. The method of claim 1 further comprising alerting a user if the indicator for presence of a blood vessel indicates that there is a blood vessel at or nearby the tip of the sensor probe.

5. The method of claim 1 further comprising instructing a user to advance the penetration sensor device towards a target location if the indicator for presence of a blood vessel indicates that the tip of the sensor probe is touching a nonvascular tissue.

6. The method of claim 1 further comprising rerouting the penetration sensor device into a different direction if the indicator for presence of a blood vessel indicates that the tip of the sensor probe is nearby or touching a blood vessel so that the blood vessel is not punctured by the penetration sensor device.

7. The method of claim 1 wherein the penetration sensor device is a dilator sensor device, a needle sensor device, or a trocar sensor device.

8. The method of claim 1 further comprising identifying the tissue as a blood vessel if the blood vessel has a diameter greater than about 3 millimeters.

9. The method of claim 1 wherein the sensor openings are located on a front face of the tip of the penetration sensor device and the distal ends of the optical fibers are aligned along a longitudinal axis of the penetration sensor device.

10. The method of claim 9 further comprising a second set of optical fibers and a second set of sensor openings on a side wall of the penetration instrument near a tip of the penetration instrument, wherein distal ends of the second set of optical fibers are aligned radially with respect to the penetration sensor device and are inserted into the second set of sensor openings.

11. The method of claim 1 wherein the optical fibers include at least one source fiber and at least one detector fiber and the sensor openings in the sensor unit are separated by a distance of at least 1 millimeter.

12. The method of claim 1 wherein the optical fibers include two source fibers and two detector fibers, and the sensor openings in the sensor unit are aligned in a linear array and are separated by a distance of at least 1 millimeter.

13. The method of claim 1 wherein the first light signal is emitted from a first sensor opening on a sensor head of the penetration sensor device, and the second light signal is received at a second opening formed on the same sensor head.

14. The method of claim 1 wherein the first and second optical fibers pass through a channel of the penetration sensor device.

15. The method of claim 1 wherein the sensor probe is slidably coupled within the lumen of the penetration instrument.

16. A method for differentiating a blood vessel from a nonvascular tissue inside a patient'"'"'s body cavity during a surgical procedure, comprising:

transmitting a first light signal through optical fibers in a penetration sensor device comprising a tip;

receiving a second light signal reflected from the tissue through the optical fibers in the penetration sensor device;

determining an indicator of presence of a blood vessel at or nearby a tip of the penetration sensor device based on information from the first light signal and the second light signal;

identifying the tissue as a blood vessel if the indicator for presence of a blood vessel is greater than a threshold,

wherein the penetration sensor device comprises a penetration instrument having a tubular body with a lumen along a longitudinal axis of the tubular body, and a sensor probe, coupled to the penetration instrument, comprising a sensor unit, at a tip of the sensor probe, having emitter and detector sensor openings, optical fibers wherein a first distal end of a first optical fiber of the optical fibers is coupled to the emitter sensor opening and a second distal end of a second optical fiber of the optical fibers is coupled to the detector sensor opening, and a connector which includes proximal ends of the optical fibers and is configured to couple the penetration sensor device to a system unit, and

the emitter and detector sensor openings are located on a side wall of the penetration instrument near a tip of the penetration instrument and the distal ends of the optical fibers are aligned radially with respect to the penetration sensor device.