Methods and devices for controlling ablation therapy

• US 9,445,861 B2
• Filed: 04/12/2012
• Issued: 09/20/2016
• Est. Priority Date: 04/12/2011
• Status: Active Grant

• Current Assignee: Thermedical, Inc.
• Original Assignee: Thermedical, Inc.
• Inventors: Curley, Michael G.
• Primary Examiner(s): Holmes, Rex R
• Application Number:
  US13/445,373
• Publication Number:
  US 20120265200A1
• Time in Patent Office: 1,622 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/04 by heating by applying electromagnetic radiation A61B18/18; hyperthermia using electric or magnetic fields, radiation or ultrasound A61N
• CPC Class Codes: A61B 18/082 Probes or electrodes therefor
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/16 Indifferent or passive electrodes for grounding
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00041 Heating, e.g. defrosting
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00773 Sensed parameters
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00809 measured thermochromatically
• CPC Class Codes: A61B 2018/00821 measured by a thermocouple
• CPC Class Codes: A61B 2018/046 in liquid form
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/162 located on the probe body
• CPC Class Codes: F04B 17/03 driven by electric motors
• CPC Class Codes: F04B 19/22 of reciprocating-piston type
• CPC Class Codes: F04B 41/02 having reservoirs
• CPC Class Codes: F04B 43/04 : Pumps having electric drive
• CPC Class Codes: F04B 49/06 : Control using electricity regulating by means of floats actuating electric switches F04B49/04
• CPC Class Codes: F04C 2270/041 : Controlled or regulated
• CPC Class Codes: Y10T 29/49016 : Antenna or wave energy "plumbing" making
• CPC Class Codes: Y10T 29/49085 : Thermally variable

Abstract

Devices and methods for controlling ablation therapy are provided herein. In one embodiment, an ablation device is provided that includes an elongate body having proximal and distal ends, and an inner lumen extending therethrough. The inner lumen can be configured to receive fluid therein and to deliver fluid to the distal end of the elongate body. The device can also include an ablation element positioned at a distal end of the elongate body that is configured to heat surrounding tissue, and a heater element disposed within the inner lumen adjacent to a distal end of thereof, the heater element being configured to heat fluid flowing through the inner lumen.

Claims

1. An ablation device, comprising:

an elongate body having proximal and distal ends, and an inner lumen extending therethrough;

a delivery lumen disposed within the inner lumen of the elongate body that is configured to deliver fluid from the proximal end to the distal end of the elongate body;

a return lumen disposed within the inner lumen of the elongate body that is configured to receive fluid delivered to the distal end of the elongate body and to return the fluid to the proximal end of the elongate body;

an ablation element that forms a blunt distal end of the elongate body, the ablation element being configured to contact tissue without penetrating through the tissue and to heat surrounding tissue; and

a heater element disposed within the inner lumen adjacent to the distal end of the elongate body, the heater element being configured to heat fluid flowing through the inner lumen to a temperature greater than 37°

C. and less than 100°

C.;

wherein the fluid delivered to the distal end of the elongate body through the delivery lumen is returned to the proximal end of the elongate body through the return lumen without being released into surrounding tissue.

2. The device of claim 1, further comprising a temperature sensor disposed on a distal end of the ablation element.

3. The device of claim 1, further comprising a temperature sensor disposed within the inner lumen of the elongate body and in contact with the ablation element.

4. The device of claim 1, wherein the heater element comprises at least one wire extending through the inner lumen and configured to pass RF electrical energy through fluid flowing through the inner lumen.

5. The device of claim 1, further comprising a temperature sensor positioned adjacent to the distal end of the inner lumen at a location distal to the heater element.

6. The device of claim 1, wherein the device is configured to deliver fluid through the at least one fluid port simultaneously while emitting radio frequency (RF) energy from the ablation element.

7. The device of claim 3, further comprising a controller configured to

detect a temperature of the ablation element using the temperature sensor;

adjust an output level of any of the ablation element and the heater element to maintain the temperature of the ablation element above 37°

C. and below 100°

C.

8. The device of claim 1, wherein the heater element includes at least one wire that extends through at least one spacer, the at least one wire being configured to pass energy through the fluid flowing through the inner lumen of the elongate body and the at least one spacer being configured to maintain a position of the at least one wire within the inner lumen of the elongate body.

9. The device of claim 8, wherein the at least one wire includes two wires and the at least one spacer includes two spacers.

10. The device of claim 8, wherein the at least one wire is covered in an electrically insulating material and is exposed for only a short distance located just proximal of the at least one outlet port.

11. The device of claim 8, wherein the elongate body is conductive, the at least one wire includes a single wire, and the ablation device further comprises:

a first power source configured to heat fluid flowing through the inner lumen by passing current between the single wire and the elongate body; and

a second power source configured to heat tissue surrounding the elongate body by passing current between the elongate body and a collector electrode positioned outside the inner lumen.

12. The device of claim 1, wherein the return lumen is defined by the annular space between the delivery lumen and an inner wall of the elongate body inner lumen.

13. The device of claim 1, wherein the delivery lumen and the return lumen are each separate hollow tubes disposed within the inner lumen of the elongate body.

14. The device of claim 1, wherein the delivery lumen is positioned within the inner lumen of the elongate body such that it does not move with respect to the elongate body.

15. The device of claim 1, wherein the delivery lumen floats freely within the inner lumen of the elongate body.

16. The device of claim 1, wherein the ablation element is formed from a non-porous material.