Pumping system and method for assisting a patient's heart

• US 9,446,183 B2
• Filed: 07/28/2015
• Issued: 09/20/2016
• Est. Priority Date: 12/31/2009
• Status: Active Grant

• Current Assignee: Cardiacassist Inc. (LivaNova Plc)
• Original Assignee: Cardiacassist Inc. (LivaNova Plc)
• Inventors: Smith, Douglas E., Wivholm, Jennifer, Svitek, Robert G., Cortese, Cory J., Bollinger, Robert, Garippa, Michael
• Primary Examiner(s): Stigell, Theodore
• Assistant Examiner(s): MAHMOOD, NADIA AHMAD
• Application Number:
  US14/810,701
• Publication Number:
  US 20150328390A1
• Time in Patent Office: 420 Days
• Field of Search: 600/16, 600/160, 600/17, 600/18
• US Class Current: 1/1
• CPC Class Codes: A61M 1/1698 Blood oxygenators with or without heat-exchangers intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/3653 Interfaces between patient blood circulation and extra-corporal blood circuit
• CPC Class Codes: A61M 1/3659 Cannulae pertaining to extracorporeal circulation
• CPC Class Codes: A61M 1/3666 Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
• CPC Class Codes: A61M 1/3667 with assisted venous return
• CPC Class Codes: A61M 2025/0004 having two or more concentrically arranged tubes for forming a concentric catheter system
• CPC Class Codes: A61M 2025/0008 having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
• CPC Class Codes: A61M 2205/32 with radio-opaque indicia
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 25/0041 pre-formed, e.g. specially adapted to fit with the anatomy of body channels urethral catheters A61F2/04
• CPC Class Codes: A61M 25/005 with embedded materials for reinforcement, e.g. wires, coils, braids
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0108 using radio-opaque or ultrasound markers
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/221 the blood flow through the rotating member having both radial and axial components, e.g. mixed flow pumps
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/237 the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
• CPC Class Codes: A61M 60/279 Peristaltic pumps, e.g. roller pumps
• CPC Class Codes: A61M 60/38 Blood oxygenation
• CPC Class Codes: A61M 60/867 : using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter

Abstract

A cannula for a patient includes an elongate body having a length of at least 70 cm and a channel extending through the body defining a wall. The cannula includes a wire embodied within at least a portion of the wall. The body has a proximal end, a distal end having a tip opening through which the channel extends and a plurality of side holes through the wall in proximity to the tip for unimpeded flow of blood at the distal end. The cannula includes a barbed fitting at the proximal end. The cannula includes a suture wing for securing the elongated body to the patient. A system for assisting a patient'"'"'s heart. A method for assisting a patient'"'"'s heart.

Claims

1. A pumping system for assisting a human patient'"'"'s heart, comprising:

a blood pump;

a drainage cannula adapted for fluid communication with an inlet to the blood pump to provide blood to the blood pump; and

a blood supply cannula adapted for fluid communication with an outlet of the blood pump to provide blood to the patient'"'"'s heart arterial system, at least one of the drainage cannula and the blood supply cannula further comprising;

an elongated body defining a channel extending through the elongated body, the elongated body having a proximal end and a distal end having a distal tip, the distal end defusing at least one of a tip opening communicating with the channel and at least one side hole in proximity to the distal tip and communicating with the channel for outflow of blood at the distal end,

wherein the drainage cannula has a length to extend from the patient'"'"'s groin to the patient'"'"'s right atrium and the blood supply cannula has a length to extend from the patient'"'"'s groin to the patient'"'"'s heart arterial system, whereby, when the blood pump operates, the patient'"'"'s heart and lungs are essentially bypassed by draining the right atrium of blood and pumping blood into the patient'"'"'s heart arterial system thereby allowing the patient'"'"'s ventricles to rest and establishing ventricular support.

2. The pumping system as claimed in claim 1, wherein the distal end of the elongated body is curved for natural anatomical placement within the patient'"'"'s heart.

3. The pumping system as claimed in claim 1, wherein at least a portion of the elongated body has insertion depth markings.

4. The pumping system as claimed in claim 1, wherein the distal tip has radiopaque markers to aid in visualization.

5. The pumping system as claimed in claim 1, further comprising a blood oxygenator between the blood supply cannula and the blood pump outlet to oxygenate the blood received from the patient'"'"'s heart into the blood pump, the blood pump supplying oxygenated blood to the patient via the blood supply cannula.

6. A method for assisting a human patient'"'"'s heart, comprising:

connecting a drainage cannula to an inlet to a blood pump to provide blood to the blood pump, the drainage cannula having a length to extend from the patient'"'"'s groin to the patient'"'"'s right atrium;

connecting a blood supply cannula to an outlet of the blood pump to provide blood to the patient, the blood supply cannula having a length to extend from the patient'"'"'s groin to the patient'"'"'s heart arterial system; and

operating the blood pump such that the patient'"'"'s ventricles are essentially bypassed by draining the right atrium of blood and pumping blood into the patient'"'"'s heart arterial system thereby allowing the patient'"'"'s ventricles to rest and establishing ventricular support.

7. The method as claimed in claim 6, wherein at least one of the drainage cannula and the blood supply cannula further comprises:

an elongated body defining a channel extending through the elongated body, the elongated body having a proximal end and a distal end having a distal tip, the distal end defining at least one of a tip opening communicating with the channel and at least one side hole in proximity to the distal tip and communicating with the channel for outflow of blood at the distal end.

8. The method as claimed in claim 7, wherein the distal end of the elongated body is curved for natural anatomical placement within the patient'"'"'s heart.

9. The method as claimed in claim 7, wherein at least a portion of the elongated body has insertion depth markings.

10. The method as claimed in claim 7, wherein the distal tip has radiopaque markers to aid in visualization.

11. The method as claimed in claim 6, further comprising oxygenating the blood received from the patient'"'"'s heart into the blood pump, the blood pump supplying oxygenated blood to the patient via the blood supply cannula.

12. A pumping system for assisting a human patient'"'"'s heart, comprising:

a blood pump;

a transseptal cannula adapted for fluid communication with an inlet to the blood pump to provide blood to the blood pump; and

an arterial cannula adapted for fluid communication with an outlet of the blood pump to provide blood to the patient'"'"'s heart, at least one of the transseptal cannula and the arterial cannula further comprising;

an elongated body defining a channel extending through the elongated body, the elongated body having a proximal end and a distal end having a distal tip, the distal end defining at least one of a tip opening communicating with the channel and at least one side hole in proximity to the distal tip and communicating with the channel for outflow of blood at the distal end,

wherein the transseptal cannula is further configured to cross the patient'"'"'s atrial septum to extend into the patient'"'"'s left atrium, whereby the patient'"'"'s left ventricle is essentially bypassed by draining the left atrium when blood is pumped by the blood pump into the patient'"'"'s heart arterial system via the arterial cannula thereby allowing the patient'"'"'s left ventricle to rest and establishing left ventricular support.

13. The pumping system as claimed in claim 12, wherein the transseptal cannula has a length to extend from the patient'"'"'s groin to the patient'"'"'s heart.

14. The pumping system as claimed in claim 12, wherein the arterial cannula has a length to extend from the patient'"'"'s groin to the patient'"'"'s heart.

15. The pumping system as claimed in claim 12, wherein the distal end of the elongated body is curved for natural anatomical placement within the patient'"'"'s heart.

16. The pumping system as claimed in claim 12, wherein the distal end of the elongated body is curved for natural anatomical placement from the inferior vena cava into the left atrium of the patient'"'"'s heart.

17. The pumping system as claimed in claim 12, wherein at least a portion of the elongated body has insertion depth markings.

18. The pumping system as claimed in claim 12, wherein the distal tip has radiopaque markers to aid in visualization.

19. The pumping system as claimed in claim 12, further comprising a blood oxygenator between the arterial cannula and the blood pump outlet to oxygenate the blood received from the patient'"'"'s heart into the blood pump, the blood pump supplying oxygenated blood to the patient via the arterial cannula.

20. A method for assisting a human patient'"'"'s heart, comprising:

connecting a transseptal cannula with an inlet to a blood pump to provide blood to the blood pump;

connecting an arterial cannula with an outlet of the blood pump to provide blood to the patient'"'"'s heart;

crossing the patient'"'"'s atrial septum using the transseptal cannula whereby the transseptal cannula extends into the patient'"'"'s left atrium; and

operating the blood pump such that the patient'"'"'s left ventricle is essentially bypassed by draining the left atrium and pumping blood into the patient'"'"'s heart arterial system via the arterial cannula thereby allowing the patient'"'"'s left ventricle to rest and establishing left ventricular support,

wherein at least one of the transseptal cannula and the arterial cannula further comprises;

an elongated body defining a channel extending through the elongated body, the elongated body having a proximal end and a distal end having a distal tip, the distal end defining at least one of a tip opening communicating with the channel and at least one side hole in proximity to the distal tip and communicating with the channel for outflow of blood at the distal end.

21. The method as claimed in claim 20, wherein the transseptal cannula has a length to extend from the patient'"'"'s groin to the patient'"'"'s heart.

22. The method as claimed in claim 20, wherein the arterial cannula has a length to extend from the patient'"'"'s groin to the patient'"'"'s heart.

23. The method as claimed in claim 20, wherein the distal end of the elongated body is curved for natural anatomical placement within the patient'"'"'s heart.

24. The method as claimed in claim 20, wherein the distal end of the elongated body is curved for natural anatomical placement from the inferior vena cava into the left atrium of the patient'"'"'s heart.

25. The method as claimed in claim 20, wherein at least a portion of the elongated body has insertion depth markings.

26. The method as claimed in claim 20, wherein the distal tip has radiopaque markers to aid in visualization.

27. The method as claimed in claim 20, further comprising oxygenating the blood received from the patient'"'"'s heart into the blood pump, the blood pump supplying oxygenated blood to the patient via the arterial cannula.