Gastric electrical stimulation with lockout interval anti-desensitization feature

• US 9,446,234 B2
• Filed: 09/24/2008
• Issued: 09/20/2016
• Est. Priority Date: 10/01/2007
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Starkebaum, Warren L., Yuan, Charlene X., Maude-Griffin, Roland C., Pivotto, Luiz Geraldo
• Primary Examiner(s): Gedeon, Brian T
• Application Number:
  US12/236,836
• Publication Number:
  US 20090088817A1
• Time in Patent Office: 2,918 Days
• Field of Search: 607/2, 607/3, 607/39, 607/40, 607/41, 607/46, 607/47, 607/115, 607/133
• US Class Current: 1/1
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

The disclosure is directed to gastric stimulation programmers, stimulators and methods for controlling delivery of gastric stimulation therapy to maintain the efficacy of the therapy over time. Maintaining the efficacy of gastric stimulation therapy may be possible by implementing one or more anti-desensitization features in a gastric stimulation controller or stimulator. As electrical stimulation therapy is continuously delivered to a patient, the stimulated tissue may become desensitized to the electrical stimulation therapy such that the beneficial effect of the electrical stimulation is diminished. Once desensitization occurs, the affected tissue may not respond favorably to electrical stimulation therapy. Application of one or more anti-desensitization features to control gastric stimulation therapy may reduce or prevent desensitization and effectively extend the efficacy of the therapy over time.

Claims

1. A device comprising:

means for receiving a request to deliver electrical gastric stimulation therapy to a patient;

means for prohibiting delivery of the gastric stimulation therapy if the request is received within a lockout period following a previous delivery of gastric stimulation therapy;

means for permitting delivery of the gastric stimulation therapy if the request is not received within a lockout period following the previous delivery of gastric stimulation therapy; and

means for prohibiting delivery of the gastric stimulation therapy if the request is not received within a time period specified by a therapy schedule.

2. The device of claim 1, further comprising means for terminating delivery of the gastric electrical stimulation therapy upon expiration of a therapy window following a start of the delivery of the gastric electrical stimulation therapy.

3. The device of claim 1, further comprising means for receiving the request from a patient via an external programmer via wireless telemetry.

4. The device of claim 1, wherein the means for permitting delivery of gastric electrical stimulation therapy comprises means for delivering the gastric electrical stimulation therapy to one of a stomach or a small intestine of the patient.

5. The device of claim 1, further comprising means for indicating at least one of a running time, a countdown, or an expiration time of the lockout period to a user via an external programmer.

6. The device of claim 1, wherein a lockout period follows each delivery of gastric stimulation therapy.

7. The device of claim 6, wherein delivery of gastric stimulation therapy comprises delivery of a burst pattern.

8. A system comprising:

a stimulator that delivers gastric electrical stimulation therapy to a patient; and

an external programmer that controls the stimulator to deliver the gastric electrical stimulation therapy,

wherein one of the programmer or the stimulator;

receives a request to deliver the electrical gastric stimulation therapy to the patient,

prohibits delivery of the gastric stimulation therapy by the stimulator if the request is received within a lockout period following a previous delivery of gastric stimulation therapy,

permits delivery of the gastric stimulation therapy by the stimulator if the request is not received within a lockout period following the previous delivery of gastric stimulation therapy, and

prohibits delivery of the gastric stimulation therapy if the request is not received within a time period specified by a therapy schedule.

9. The system of claim 8, wherein one of the programmer or the stimulator terminates delivery of the gastric electrical stimulation therapy upon expiration of a therapy window following a start of the delivery of the gastric electrical stimulation therapy.

10. The system of claim 8, wherein the request is received from a patient via the programmer via wireless telemetry.

11. The system of claim 8, wherein the stimulator is configured to deliver the gastric electrical stimulation therapy to treat a disorder of one of a stomach or a small intestine of the patient.

12. The system of claim 8, wherein the programmer is configured to indicate at least one of a running time, a countdown, or an expiration time of the lockout period to a user.

13. The system of claim 8, wherein a lockout period follows each delivery of gastric stimulation therapy.

14. The system of claim 13, wherein delivery of gastric stimulation therapy comprises delivery of a burst pattern.

15. An external programmer for a gastric electrical stimulator, the programmer comprising:

a user interface that receives a request to deliver the gastric electrical stimulation therapy to a patient; and

a processor that controls the gastric electrical stimulator to;

prohibit delivery of the gastric electrical stimulation therapy by the stimulator if the request is received within a lockout period following a previous delivery of gastric electrical stimulation therapy,

permit delivery of the gastric electrical stimulation therapy by the stimulator if the request is not received within a lockout period following the previous delivery of gastric stimulation therapy, and

prohibits delivery of the gastric stimulation therapy if the request is not received within a time period specified by a therapy schedule.

16. The programmer of claim 15, wherein the programmer controls the stimulator to terminate delivery of the gastric electrical stimulation therapy upon expiration of a therapy window following a start of the delivery of the gastric electrical stimulation therapy.

17. The programmer of claim 15, wherein programmer includes a user interface that receives the request from the patient.

18. The programmer of claim 15, wherein the programmer is configured to control the stimulator to deliver the gastric electrical stimulation therapy to treat a disorder of one of a stomach or a small intestine of the patient.

19. The programmer of claim 15, wherein the programmer includes a user interface configured to indicate at least one of a running time, a countdown, or an expiration time of the lockout period to a user.

20. The programmer of claim 15, wherein a lockout period follows each delivery of gastric stimulation therapy.

21. The programmer of claim 20, wherein delivery of gastric stimulation therapy comprises delivery of a burst pattern.

22. A gastric electrical stimulator comprising:

a stimulation generator that delivers gastric electrical stimulation therapy;

an interface that receives a request to deliver the electrical gastric stimulation therapy to a patient; and

a processor that controls the stimulation generator such that the stimulator generator prohibits delivery of the gastric stimulation therapy by the stimulator if the request is received within a lockout period following a previous delivery of gastric stimulation therapy, permits delivery of the gastric stimulation therapy by the stimulator if the request is not received within a lockout period following the previous delivery of gastric stimulation therapy, and prohibits delivery of the gastric stimulation therapy if the request is not received within a time period specified by a therapy schedule.

23. The stimulator of claim 22, wherein the processor controls the stimulation generator to terminate delivery of the gastric electrical stimulation therapy upon expiration of a therapy window following a start of the delivery of the gastric electrical stimulation therapy.

24. The stimulator of claim 22, wherein the interface receives the request from the programmer via wireless telemetry.

25. The stimulator of claim 22, wherein the stimulation generator is configured to deliver the gastric electrical stimulation therapy to treat a disorder of one of a stomach or a small intestine of the patient.

26. The stimulator of claim 22, wherein a lockout period follows each delivery of gastric stimulation therapy.

27. The stimulator of claim 26, wherein delivery of gastric stimulation therapy comprises delivery of a burst pattern.