Vaccinia virus H3L and B5R specific monoclonal antibodies and methods of making and using same
First Claim
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1. An isolated or purified antibody or subsequence thereof that binds to an H3L envelope protein of vaccinia virus, wherein the antibody or subsequence comprises heavy chain and light chain variable region sequence CDRs identical to heavy chain and light chain variable region sequence CDRs of an antibody produced by a hybridoma deposited at American Type Culture Collection having a deposit designation of PTA-10767.
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Abstract
The invention relates to antibodies and subsequences thereof that specifically bind to poxvirus B5R envelope protein, antibodies and subsequences thereof that specifically bind to poxvirus H3L envelope protein, and combinations thereof.
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Citations
19 Claims
- 1. An isolated or purified antibody or subsequence thereof that binds to an H3L envelope protein of vaccinia virus, wherein the antibody or subsequence comprises heavy chain and light chain variable region sequence CDRs identical to heavy chain and light chain variable region sequence CDRs of an antibody produced by a hybridoma deposited at American Type Culture Collection having a deposit designation of PTA-10767.
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2. An isolated or purified antibody or subsequence thereof that binds to an H3L envelope protein of vaccinia virus, wherein the antibody or subsequence comprises a heavy chain variable region sequence and a light chain variable region sequence identical to a heavy chain variable region sequence and a light chain variable region sequence of an antibody produced by a hybridoma deposited at American Type Culture Collection having a deposit designation of PTA-10767.
Specification