Reducing flow through a tubular structure

• US 9,451,965 B2
• Filed: 04/16/2015
• Issued: 09/27/2016
• Est. Priority Date: 06/29/2010
• Status: Active Grant

• Current Assignee: ArtVentive Medical Group Inc
• Original Assignee: ArtVentive Medical Group Inc
• Inventors: Rudakov, Leon, Gailloud, Philippe
• Primary Examiner(s): TANNER, JOCELIN C
• Application Number:
  US14/688,915
• Publication Number:
  US 20150223821A1
• Time in Patent Office: 530 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/1204 temporary occlusion
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/00469 for insertion of instruments, e.g. guide wire, optical fibre
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/1209 detachable by electrical current or potential, e.g. electroactive polymer
• CPC Class Codes: A61B 2017/22035 for retrieving or repositioning foreign objects

Abstract

A method for reducing or stopping flow through a tubular structure of a patient can include positioning an elongate member within a lumen of the tubular structure. The elongate member can be arranged to form a frame having a distal opening and a proximal opening. The elongate member can substantially reduce or totally obstruct, with a flow reducing member coupled to the frame, flow of at least one of emboli and fluid flowing through the lumen. The flow reducing member can comprise a one-way valve that moves in response to fluid flow to substantially prevent distal flow through the distal opening and to allow proximal flow through the distal opening.

Claims

1. A method for reducing or stopping flow through a tubular structure of a patient, the method comprising:

positioning a first elongate member within a lumen of the tubular structure, the first elongate member arranged to form a first frame having a distal opening and a proximal opening, the first frame configured to be positioned within a lumen of the tubular structure, the first frame having a proximal portion, a distal portion, and a middle portion therebetween, the distal portion tapered such that an outer cross-sectional dimension of the distal opening is less than an outer cross-sectional dimension of the middle portion, the first frame coupled to a first flow reducing member, the first flow reducing member being disposed over an exterior of the first frame and over the distal portion with at least a portion of the first flow reducing member extending from the exterior of the first frame into an interior of the first frame through the distal opening to form a flap in the interior of the first frame, the flap configured to operate as a one-way valve that moves in response to fluid flow to substantially prevent distal flow through the distal opening and to allow proximal flow through the distal opening; and

substantially reducing or totally obstructing, with the first flow reducing member, flow of at least one of emboli and fluid flowing through the lumen.

2. The method of claim 1, further comprising removing the first frame from within the lumen by inverting the first frame such that the distal portion moves within and toward the middle portion.

3. The method of claim 1, further comprising:

extending a tube through the distal opening to position the tube at a target site of the patient; and

applying, with a vacuum source, a vacuum through the tube for removing at least one of emboli and fluid from the target site.

4. The method of claim 1, wherein the first flow reducing member is disposed over the exterior of the first frame and over the distal portion with at least a portion of the first flow reducing member extending from the exterior of the first frame into the interior of the first frame through the distal opening to form a single flap in the interior of the first frame, the single flap configured to operate as the one-way valve.

5. The method of claim 1, further comprising positioning a second elongate member within the lumen.

6. The method of claim 5, wherein the second elongate member comprises a second frame having a distal opening, a proximal opening, a proximal portion, a distal portion, and a middle portion therebetween, the second frame distal portion tapered such that an outer cross-sectional dimension of the second frame distal opening is less than an outer cross-sectional dimension of the second frame middle portion.

7. The method of claim 5, wherein the second elongate member is positioned in the lumen before the first elongate member is removed.

8. The method of claim 7, further comprising substantially reducing or totally obstructing, with a second flow reducing member coupled to the second frame, flow of at least one of emboli or fluid flowing through the lumen.

9. The method of claim 8, wherein the second flow reducing member comprising a one-way valve that moves in response to fluid flow to substantially prevent distal flow through the distal opening and to allow proximal flow through the distal opening.

10. The method of claim 5, further comprising removing the second frame from within the lumen by inverting the second frame such that the second frame distal portion moves within and toward the second frame middle portion.

11. The method of claim 5, wherein the tubular structure comprises a tumor-feeding branch vessel branching from the tubular structure at a target site, and wherein the first elongate member is positioned downstream of the target site and the second elongate member is positioned upstream of the target site.

12. A method for reducing or stopping flow through a tubular structure of a patient, the method comprising:

positioning an outer catheter within a lumen of the tubular structure at a first deployment site, wherein an inner catheter is disposed within the outer catheter, wherein a first elongate member is positioned between the inner catheter and the outer catheter, the first elongate member arranged to form a first frame having a distal opening and a proximal opening, the first frame having a proximal portion, a distal portion, and a middle portion therebetween, the distal portion tapered such that an outer cross-sectional dimension of the distal opening is less than an outer cross-sectional dimension of the middle portion, the first frame coupled to a first flow reducing member, the first flow reducing member being disposed over an exterior of the first frame and over the distal portion with at least a portion of the first flow reducing member extending from the exterior of the first frame into an interior of the first frame through the distal opening to form a flap in the interior of the first frame, the flap configured to operate as a one-way valve that moves in response to fluid flow to substantially prevent distal flow through the distal opening and to allow proximal flow through the distal opening;

partially deploying the first frame from the outer catheter by shifting the inner catheter distally relative to the outer catheter until a portion of the first frame extends beyond a distal opening of the outer catheter into the first deployment site;

retracting the first frame into the outer catheter by shifting the inner catheter proximally relative to the outer catheter until the portion of the first frame is retracted proximally into the outer catheter;

positioning the outer catheter within the lumen at a second deployment site for deploying the first frame at the second deployment site;

deploying the first frame from the outer catheter by shifting the inner catheter distally relative to the outer catheter until the first frame extends beyond the distal opening of the outer catheter into the second deployment site; and

substantially reducing or totally obstructing, with the first flow reducing member coupled to the first frame, flow of at least one of emboli and fluid flowing through the lumen.

13. The method of claim 12, wherein the substantially reducing or totally obstructing comprises substantially reducing or totally obstructing flow of at least one of emboli and fluid flowing through the lumen using the one-way valve.

14. The method of claim 13, wherein the first flow reducing member is disposed over the exterior of the first frame and over the distal portion with at least a portion of the first flow reducing member extending from the exterior of the first frame into the interior of the first frame through the distal opening to form a single flap in the interior of the first frame, the single flap configured to operate as the one-way valve.

15. The method of claim 12, further comprising removing the first frame from within the lumen by inverting the first frame such that the distal portion moves within and toward the middle portion.

16. The method of claim 12, further comprising:

extending a tube through the distal opening to position the tube at a target site of the patient; and

applying, with a vacuum source, a vacuum through the tube for removing at least one of emboli and fluid from the target site.

17. The method of claim 12, further comprising positioning a second elongate member within the lumen.

18. The method of claim 17, wherein the second elongate member is positioned in the lumen before the first elongate member is removed.

19. The method of claim 17, wherein the second elongate member comprises a second frame having a distal opening, a proximal opening, a proximal portion, a distal portion, and a middle portion therebetween, the second frame distal portion tapered such that an outer cross-sectional dimension of the second frame distal opening is less than an outer cross-sectional dimension of the second frame middle portion.

20. The method of claim 19, further comprising substantially reducing or totally obstructing, with a second flow reducing member coupled to the second frame, flow of at least one of emboli or fluid flowing through the lumen.

21. The method of claim 20, wherein the second flow reducing member comprising a one-way valve that moves in response to fluid flow to substantially prevent distal flow through the distal opening and to allow proximal flow through the distal opening.

22. The method of claim 17, further comprising removing the second frame from within the lumen by inverting the second frame such that the second frame distal portion moves within and toward the second frame middle portion.

23. The method of claim 17, wherein the tubular structure comprises a tumor-feeding branch vessel branching from the tubular structure at a target site, and wherein the first elongate member is positioned downstream of the target site and the second elongate member is positioned upstream of the target site.