Synthesis of long-chain polyunsaturated fatty acids by recombinant cell
First Claim
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1. A cell comprising eicosapentaenoic acid in an esterified form as part of triacylglycerols in the cell and an exogenous polypeptide having Δ
- 5 desaturase activity whose amino acid sequence is at least 90% identical to the amino acid sequence set forth as SEQ ID NO;
60.
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Abstract
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.
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11 Claims
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1. A cell comprising eicosapentaenoic acid in an esterified form as part of triacylglycerols in the cell and an exogenous polypeptide having Δ
- 5 desaturase activity whose amino acid sequence is at least 90% identical to the amino acid sequence set forth as SEQ ID NO;
60. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- 5 desaturase activity whose amino acid sequence is at least 90% identical to the amino acid sequence set forth as SEQ ID NO;
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