Systems, methods, and devices for assessing microbiota of skin
First Claim
1. A system for assessing microbiota of skin comprising:
- a skin-covering material having an inner surface and an outer surface, the inner surface substantially conforming in shape to a topography of a skin surface of an individual and including associated thereto a plurality of specific microbe-binding elements;
an image-capture device including circuitry to capture at least one image of the inner surface of the skin-covering material and to transform the captured at least one image into a digital output including information associated with at least one property and a spatial distribution of at least one type of microbe bound to at least one of the plurality of specific microbe-binding elements; and
a computing device including a processor, the computing device operably coupled to the image-capture device and including circuitry configured toreceive the digital output from the image-capture device including the information associated with the at least one property and the spatial distribution of the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements associated with the inner surface of the skin-covering material;
compare the at least one property of the at least one type of microbe with a database of reference microbe properties; and
generate a digital profile including the at least one property and the spatial distribution of the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements.
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Accused Products
Abstract
Devices, systems, and methods for assessing microbiota of skin are described which include: a skin-covering material with an inner surface conforming in shape to a topography of a skin surface and including a plurality of specific microbe-binding elements; an image capture device to capture an image of the inner surface of the skin-covering material and to transform the image into a digital output including information associated with at least one property and a spatial distribution of at least one type of microbe bound to the specific microbe-binding elements; and a computing device including circuitry configured to receive the digital output from the image-capture device, compare the at least one property of the at least one type of microbe bound to the specific microbe-binding elements with a database of reference microbe properties, and generate a digital profile including the at least one property and the spatial distribution of the at least one type of microbe bound to the specific microbe-binding elements.
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Citations
28 Claims
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1. A system for assessing microbiota of skin comprising:
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a skin-covering material having an inner surface and an outer surface, the inner surface substantially conforming in shape to a topography of a skin surface of an individual and including associated thereto a plurality of specific microbe-binding elements; an image-capture device including circuitry to capture at least one image of the inner surface of the skin-covering material and to transform the captured at least one image into a digital output including information associated with at least one property and a spatial distribution of at least one type of microbe bound to at least one of the plurality of specific microbe-binding elements; and a computing device including a processor, the computing device operably coupled to the image-capture device and including circuitry configured to receive the digital output from the image-capture device including the information associated with the at least one property and the spatial distribution of the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements associated with the inner surface of the skin-covering material; compare the at least one property of the at least one type of microbe with a database of reference microbe properties; and generate a digital profile including the at least one property and the spatial distribution of the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A method comprising:
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receiving a digital output from an image-capture device, the digital output including information associated with at least one property and a spatial distribution of at least one type of microbe bound to at least one of a plurality of specific microbe-binding elements associated with an inner surface of a skin-covering material; identifying the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements by comparing the information associated with the at least one property of the at least one type of microbe with a database of reference microbe properties; and reporting to a user an identification and spatial profile of the identified at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements associated with the inner surface of the skin-covering material. - View Dependent Claims (19, 20, 21, 22)
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23. A method comprising:
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applying a skin-covering material to a skin surface of an individual, the skin-covering material including an inner surface and an outer surface, the inner surface substantially conforming in shape to a topography of the skin surface of the individual and including associated thereto a plurality of specific microbe-binding elements; removing the skin-covering material from the skin surface of the individual; capturing at least one image of the inner surface of the skin-covering material with an image-capture device and transforming the captured at least one image into a digital output, the digital output including information associated with at least one property and a spatial distribution of at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements associated with the inner surface of the skin-covering material; receiving the digital output from the image-capture device, the digital output including the information associated with the at least one property and the spatial distribution of the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements associated with the inner surface of the skin-covering material; identifying the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements by comparing the information associated with the at least one property of the at least one type of microbe with a database of reference microbe properties; and reporting to a user an identification and spatial profile of the identified at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements associated with the inner surface of the skin-covering material. - View Dependent Claims (24, 25, 26, 27)
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28. An article of manufacture comprising:
non-transitory machine readable media bearing one or more instructions for assessing microbiota of skin, the one or more instructions including one or more instructions for receiving a digital output from an image-capture device, the digital output including information associated with at least one property and a spatial distribution of at least one type of microbe bound to at least one of a plurality specific microbe-binding elements on an inner surface of a skin-covering material; one or more instructions for identifying the at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements by comparing the information associated with the at least one property of the at least one type of microbe with a database of reference microbe properties; one or more instructions for generating a digital alignment of the spatial distribution of the identified at least one type of microbe bound to the at least one of the plurality of specific microbe-binding elements on the inner surface of the skin-covering material with a digital image of a skin surface of an individual covered by the inner surface of the skin-covering material; one or more instructions for generating a personalized microbe profile from the digital alignment, the personalized microbe profile including the identity of the at least one type of microbe and the spatial distribution of the at least one type of microbe on the skin surface of the individual; one or more instructions for comparing the personalized microbe profile with a reference microbe profile; one or more instructions for generating a recommended treatment regimen for the individual based on the comparison of the personalized microbe profile with the reference microbe profile; and one or more instructions for reporting to a user at least one of the personalized microbe profile or the recommended treatment regimen.
Specification