Embolic devices
First Claim
Patent Images
1. An expansile device for implantation comprising:
- a polymeric filament including about 25% w/w poly (ethylene glycol) 10,000 macromer;
about 11% w/w of an ethylenically unsaturated monomer; and
about 63% w/w barium sulfate;
an introducer configured to be connected to a catheter;
a first pressurized liquid configured to flush the polymeric filament out of the introducer and into the catheter, wherein the first pressurized liquid has a pressure of between about 50 psi and about 200 psi; and
a second pressurized liquid configured to flush the polymeric filament out of the catheter, wherein the second pressurized liquid has a pressure of between about 60 psi and about 140 psi,wherein the expansile device includes no metal support members.
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Abstract
Described herein are apparatus, compositions, systems and associated methods to occlude structures and malformations of the vasculature with radiopaque hydrogel filaments with delayed controlled rates of expansion. Further described is a device for implantation in an animal comprising a difunctional, low molecular weight ethylenically unsaturated shapeable macromer; an ethylenically unsaturated monomer; and a radiopaque element, wherein said device contains no support members. Methods of forming such devices are also disclosed.
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Citations
19 Claims
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1. An expansile device for implantation comprising:
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a polymeric filament including about 25% w/w poly (ethylene glycol) 10,000 macromer;
about 11% w/w of an ethylenically unsaturated monomer; and
about 63% w/w barium sulfate;an introducer configured to be connected to a catheter; a first pressurized liquid configured to flush the polymeric filament out of the introducer and into the catheter, wherein the first pressurized liquid has a pressure of between about 50 psi and about 200 psi; and a second pressurized liquid configured to flush the polymeric filament out of the catheter, wherein the second pressurized liquid has a pressure of between about 60 psi and about 140 psi, wherein the expansile device includes no metal support members. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An expansile device for implantation comprising:
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a polymeric filament including about 29% w/w poly (ethylene glycol) 10,000 macromer;
about 12% w/w of an ethylenically unsaturated monomer; and
about 58% w/w barium sulfate;an introducer configured to be connected to a catheter; a first pressurized liquid configured to flush the polymeric filament out of the introducer and into the catheter, wherein the first pressurized liquid has a pressure of between about 50 psi and about 200 psi; and a second pressurized liquid configured to flush the polymeric filament out of the catheter, wherein the second pressurized liquid has a pressure of between about 60 psi and about 140 psi, wherein the expansile device includes no metal support members; and wherein a bending resistance of the polymeric filament in a wet state is about 2 mg to about 50 mg. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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Specification