Microfabricated artificial lung assist device, and methods of use and manufacture thereof
First Claim
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1. An extracorporeal membrane oxygenator device, comprising a plurality of bi-layer structures arranged in a stack, each bi-layer structure comprising:
- a first polymer layer defining a plurality of blood flow channels within a surface thereof, wherein at least a subset of the plurality of blood flow channels each have a plurality of ribs running along the length of their respective blood flow channel, and wherein the length of each of the plurality of ribs is less than the total length of the respective blood flow channel along which it runs;
a second polymer layer defining a plurality of gas flow channels within a surface thereof, wherein the second polymer layer is aligned with the first polymer layer such that the plurality of gas flow channels overlap the plurality of blood flow channels; and
a gas permeable membrane coupled between the surface of the first polymer layer and the surface of the second polymer layer and supported by the plurality of ribs included in the subset of the plurality of blood flow channels.
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Abstract
The invention provides systems and methods for exchanging gas in an oxygenator device, and methods for preparing and using such oxygenator devices. The systems and methods can be used to transfer oxygen to blood to assist lung function in a patient.
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10 Claims
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1. An extracorporeal membrane oxygenator device, comprising a plurality of bi-layer structures arranged in a stack, each bi-layer structure comprising:
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a first polymer layer defining a plurality of blood flow channels within a surface thereof, wherein at least a subset of the plurality of blood flow channels each have a plurality of ribs running along the length of their respective blood flow channel, and wherein the length of each of the plurality of ribs is less than the total length of the respective blood flow channel along which it runs; a second polymer layer defining a plurality of gas flow channels within a surface thereof, wherein the second polymer layer is aligned with the first polymer layer such that the plurality of gas flow channels overlap the plurality of blood flow channels; and a gas permeable membrane coupled between the surface of the first polymer layer and the surface of the second polymer layer and supported by the plurality of ribs included in the subset of the plurality of blood flow channels. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification