Method and device for improving glycemic control

• US 9,457,145 B2
• Filed: 01/20/2011
• Issued: 10/04/2016
• Est. Priority Date: 01/20/2010
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Inventors: Yodfat, Ofer, Shapira, Gali, Gescheit, Iddo M.
• Primary Examiner(s): Stigell, Theodore
• Assistant Examiner(s): KOO, BENJAMIN K
• Application Number:
  US13/574,165
• Publication Number:
  US 20130030358A1
• Time in Patent Office: 2,084 Days
• Field of Search: 604/65, 604/66, 604/67, 604/503, 604/504
• US Class Current: 1/1
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Systems, devices and methods are presented in the subject disclosure for recommending an insulin dose adapted for use with an insulin delivery device. In some embodiments, the method may include receiving blood glucose (BG) data, determining one or more insulin sensitivity (IS) values associated with the BG data, and determining an insulin dose based on the determined one or more IS values. A system for carrying out such a method is also presented.

Claims

1. A method for recommending an insulin dose adapted for use with an insulin delivery device, the method comprising:

providing the insulin delivery device comprising;

a housing containing therein a pump for dispensing the insulin bolus dose into a body of a user;

input means for receiving blood glucose (BG) data;

a remote control containing therein a processor having a dose advisor application thereon configured to determine insulin sensitivity (IS) values based on corresponding BG ranges having the following IS values;

BG<

50→

IS=170mg/dL/U, 50<

=BG<

70→

IS=130mg/dL/U, 70<

=BG<

=150→

IS=100mg/dL/U, 150<

=BG<

=200→

IS=80mg/dL/U, 200<

BG<

=250→

IS=60mg/dL/U, 250<

BG<

=300→

IS=50mg/dL/U, and 300<

BG→

IS=40mg/dL/U;

a memory for storing the BG data and the IS values; and

a display for presenting output associated with the IS values which comprises an IS value used for an insulin bolus dose determination and a determined insulin bolus dose;

receiving the BG data comprising a BG level;

determining one of the IS values associated with the BG data via the dose advisor application;

receiving input from the user as to an amount of carbohydrates (Carbs) the user is about to consume;

receiving, via the dose advisor application, a carbohydrate to insulin ratio (CIR), a target blood glucose level (TBG), and a residual insulin level (RI);

calculating the determined insulin bolus dose using the equation;

(Carbs/CIR)+(BG−

TBG)/IS−

RI; and

displaying the IS value used for the insulin bolus dose determination and the determined insulin bolus dose as the recommended insulin dose.

2. The method of claim 1, wherein the BG data further comprises a BG trend.

3. The method of claim 1, wherein receiving BG data includes at least one of:

receiving an input from a user, and receiving a signal from a glucose monitor.

4. The method of claim 1, further comprising visually presenting the one or more IS values as a function of BG data.

5. The method of claim 4, wherein visually presenting includes presenting a graph or a table showing matching between the IS values and the BG data.

6. The method of claim 1, further comprising retrieving from the memory the one or more IS values associated with BG data.