Dementia differentiation device

• US 9,462,972 B2
• Filed: 07/17/2013
• Issued: 10/11/2016
• Est. Priority Date: 07/18/2012
• Status: Active Grant

• Current Assignee: University of Tokyo
• Original Assignee: University of Tokyo
• Inventors: Yamaguchi, Yasuhiro, Ouchi, Yasuyoshi, Hibi, Shinichiro
• Primary Examiner(s): VOORHEES, CATHERINE M
• Application Number:
  US14/415,550
• Publication Number:
  US 20150257696A1
• Time in Patent Office: 1,182 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/1123 Discriminating type of movement, e.g. walking or running A61B5/1116, A61B5/112 take precedence
• CPC Class Codes: A61B 5/4088 Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/6828 Leg
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A leg movement acquisition unit 1 continuously acquires leg movements of a sleeping subject. An apnea detection unit 2 detects whether or not the subject is in a state of apnea. A movement analysis unit 3 determines whether or not the detected leg movement satisfies previously determined conditions. These previously determined conditions include at least the following conditions (a) to (d): (a) The duration of leg movement is within a previously determined range; (b) intensity of leg movement is a previously determined value or greater; (c) leg movements satisfying conditions (a) and (b) continue for a previously determined number of times within a previously determined duration; and (d) the leg movement is not movement from immediately before to immediately after an apnea state that has been detected by the apnea detection unit. A coefficient calculation unit 4 calculates a coefficient based on the number of times of leg movement that satisfied the previously determined conditions. An output unit 6 outputs the coefficient or a determination result based on the coefficient.

Claims

1. A dementia differentiation device, comprising a leg movement acquisition unit, an apnea detection unit, a movement analysis unit a coefficient calculation unit and an output unit, wherein

the leg movement acquisition unit continuously acquires leg movements of a sleeping subject,

the apnea detection unit detects whether or not the subject is in a state of apnea, and

the movement analysis unit determines whether or not the leg movements satisfy previously determined conditions,

the previously determined conditions including at least the following conditions (a) to (d):

(a) the duration of leg movement is within a previously determined range;

(b) the intensity of leg movement is a previously determined value or greater;

(c) leg movements satisfying conditions (a) and (b) continue a previously determined number of times within a previously determined duration; and

(d) the leg movement is not movement from immediately before until immediately after a state of apnea that has been detected by the apnea detection unit, and wherein

the coefficient calculation unit calculates a coefficient based on the number of times of leg movement that satisfied the previously determined conditions, and

the output unit outputs either the coefficient or a determination result based on the coefficient.

2. The dementia differentiation device of claim 1, further comprising a comparison unit, wherein

the comparison unit determines the determination result by comparing a threshold value for determining whether or not a symptom is lewy body dementia and the coefficient that has been calculated by the coefficient calculation unit, and

the output unit outputs the determination result that has been determined by the comparison unit.

3. The dementia differentiation device of claim 1, wherein the coefficient based on the number of times of leg movement is an average number of times per unit duration of the leg movement that satisfied the previously determined conditions, for the sleeping subject.

4. The dementia differentiation device of claim 1, wherein the leg movement acquisition unit acquires the leg movement by measuring myoelectric potential of a leg of the subject.

5. A computer program, for operation of a dementia differentiation device comprising a leg movement acquisition unit, an apnea detection unit, a movement analysis unit, a coefficient calculation unit and an output unit, wherein

leg movement of a sleeping subject that has been acquired by the leg movement acquisition unit, and a detection result as to whether or not the subject is in a state of apnea, that has been detected by the apnea detection unit, are used,

and the computer causes the movement analysis unit to execute a step of determining whether or not the leg movements satisfy previously determined conditions,

the previously determined conditions including at least the following conditions (a) to (d):

(a) the duration of leg movement is within a previously determined range;

(b) the intensity of leg movement is a previously determined value or greater;

(c) leg movements satisfying conditions (a) and (b) continue a previously determined number of times within a previously determined duration; and

(d) the leg movement is not movement from immediately before until immediately after a state of apnea that has been detected by the apnea detection unit, and wherein

this computer program further causing a computer to execute

a step of causing the coefficient calculation unit to calculate a coefficient based on the number of times of leg movement that satisfied the previously determined conditions, and

a step of causing the output unit to output of either the coefficient or a determination result based on the coefficient.

6. An operating method for a dementia differentiation device, wherein

leg movement of a sleeping subject and a detection result as to whether or not the subject is in a state of apnea are used,

and a step of the movement analysis unit of the dementia differentiation device determining whether or not the leg movements satisfy previously determined conditions is provided,

the previously determined conditions including at least the following conditions (a) to (d):

(a) the duration of leg movement is within a previously determined range;

(b) the intensity of leg movement is a previously determined value or greater;

(c) leg movements satisfying conditions (a) and (b) continue a previously determined number of times within a previously determined duration; and

(d) the leg movement is not movement from immediately before until immediately after a state of apnea of the subject, and wherein

the method further comprises

a step of the coefficient calculation unit of the dementia differentiation device calculating a coefficient based on the number of times of leg movement that satisfied the previously determined conditions, and

a step of the output unit of the dementia differentiation device outputting either the coefficient or a determination result based on the coefficient.