Tissue modification devices

• US 9,463,029 B2
• Filed: 03/03/2014
• Issued: 10/11/2016
• Est. Priority Date: 12/07/2007
• Status: Active Grant

• Current Assignee: Spinal Elements, Inc.
• Original Assignee: Amendia, Inc. (Spinal Elements, Inc.)
• Inventors: Schmitz, Gregory P., Wallace, Michael P., Leguidleguid, Ronald, Cantorna, Nestor C., Shapiro, James, Bleich, Jeffery L.
• Primary Examiner(s): BATES, DAVID W
• Application Number:
  US14/195,197
• Publication Number:
  US 20140180293A1
• Time in Patent Office: 953 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/149 Chain, wire or band saws
• CPC Class Codes: A61B 17/1631 Special drive shafts, e.g. flexible shafts A61B17/1642, A61B17/164 take precedence
• CPC Class Codes: A61B 17/1659 Surgical rasps, files, planes, or scrapers
• CPC Class Codes: A61B 17/1671 for the spine
• CPC Class Codes: A61B 17/1735 for rasps or chisels
• CPC Class Codes: A61B 17/320016 Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes A61B10/0233, A61B17/29, A61B17/3207 take precedence
• CPC Class Codes: A61B 17/32002 with continuously rotating, oscillating or reciprocating cutting instruments
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/00261 Discectomy
• CPC Class Codes: A61B 2017/320004 abrasive
• CPC Class Codes: A61B 2017/320008 Scrapers
• CPC Class Codes: A61B 2017/32006 with a cutting strip, band or chain, e.g. like a chainsaw

Abstract

Described herein are elongate devices for modifying tissue having a plurality of flexibly connected rungs or links, and methods of using them, including methods of using them to decompress stenotic spinal tissue. These devices may be included as part of a system for modifying tissue. In general, these devices include a plurality of blades positioned on (or formed from) rungs that are flexibly connected. The rungs are typically rigid, somewhat flat and wider than they are long (e.g., rectangular). The rungs may be arranged, ladder like, and may be connected by a flexible connector substrate or between two or more cables. Different sized rungs may be used. The blades (on the rungs) may be arranged in a staggered arrangement. A tissue-collection or tissue capture element may be used to collect the cut or modified tissue.

Claims

1. A method of modifying tissue, the method comprising:

passing a guidewire at least partially around the target tissue; and

pulling a flexible tissue-modification device having a tissue collection region around the target tissue using the guidewire, wherein the flexible tissue-modification device comprises;

a flexible elongate body having a width and a thickness and a plurality of parallel rungs extending perpendicularly transverse to the proximal and distal axis, each attached to the flexible elongate body, wherein a base portion of each rung is detached from the base portion of each other rung and extends at least partially across the width of the body, wherein the rungs being detached from each other forms gaps between adjacent pairs of rungs, and at least one cutting edge on two or more of the rungs, and wherein the tissue collection region opens within the gap allowing tissue to enter through the gap between the rungs and kept between or below the rungs and prevented from moving back out;

moving the tissue-modification device against the target tissue by pulling the tissue-modification device from at least one end of the device;

cutting the target tissue with the cutting edges on the rungs of the tissue-modification device; and

collecting the cut tissue in the tissue collection region by packing the cut tissue between and below the rungs.

2. The method of claim 1, further comprising collecting cut tissue into a tissue collection portion of the tissue-modification device.

3. The method of claim 1, wherein the target tissue comprises tissue within a spinal foramen.

4. The method of claim 1, wherein the step of moving the tissue-modification device against the target tissue comprises applying tension to both the proximal end and the distal end of the tissue-modification device to drive the tissue-modification device against the target tissue.

5. The method of claim 1, further comprising the step of detecting neuronal tissue near the flexible tissue-modification device.

6. A method of removing tissue from a patient, the method comprising:

passing a flexible tissue-modification device having a tissue collection region at least partially around a target tissue, wherein the flexible tissue-modification device comprises;

a flexible elongate body extending in a proximal to distal axis along a length, the elongate body comprising a plurality of parallel rungs extending perpendicularly transverse to the proximal and distal axis, the elongate body having an anterior surface including the anterior surface of the rungs, and a plurality of cutting edges extending from the anterior surface of the rungs, wherein a base portion of each rung is spaced away from the base portion of each adjacent rung thereby forming a gap between the base portions of adjacent rungs of the plurality of rungs, wherein the base portion of each rung is attached to a flexible substrate of the elongate body, and wherein the tissue collection region opens through the anterior surface within the gaps between the base portion of adjacent rungs of the plurality of rungs allowing tissue to enter through the gap between the rungs and kept between or below the rungs and prevented from moving back out;

moving the tissue-modification device against the target tissue by pulling the tissue-modification device from at least one end of the device;

cutting the target tissue with the cutting edges; and

collecting the cut tissue in the tissue collection region by packing the cut tissue between and below the rungs.

7. The method of claim 6, wherein the step of passing the flexible tissue-modification device at least partially around the target tissue comprises:

passing a guidewire around the target tissue; and

pulling the flexible tissue-modification device around the target tissue using the guidewire.

8. The method of claim 6, wherein the target tissue comprises tissue within a spinal foramen.

9. The method of claim 6, wherein the step of moving the tissue-modification device against the target tissue comprises applying tension to both the proximal end and the distal end of the tissue-modification device to drive the tissue-modification device against the target tissue.

10. The method of claim 6, further comprising the step of sensing neuronal tissue near the flexible tissue-modification device.