Systems and methods for a computational medical device in dynamic body systems
First Claim
1. A computational catheter device, useful in association with a dynamic body system, the computational catheter device comprising:
- at least one fluid pathway;
at least one pressure sensor configured to generate a pressure signal within an anatomical vessel for a dynamic body system;
at least one external sensor configured to collect a fundamental frequency generated by at least one of a cardiovascular pulsation and external oscillator;
a modeler configured to generate a predicted signal through the anatomical vessel using the collected fundamental frequency; and
a spectral analyzer configured to generate a calibration by comparing the predicted signal to the pressure signal to identify obstructions within the anatomical vessel.
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Abstract
A computational catheter device including at least one lumen, pressure sensor(s), external sensor(s), a signal modeler, and a signal analyzer is provided. The pressure sensor generates a pressure signal for a dynamic body system, whereas the external sensor determines the fundamental frequency caused by cardiovascular pulsation or external oscillator. The signal modeler uses catheter location and the fundamental frequency to generate a predicted signal. This predicted signal may be compared to the actual pressure signal by the signal analyzer to generate a calibration. This calibration may include any of a measure of perivascular state, a waveform output which causes standing waves within the dynamic body system, a boundary condition for safe operations, and an indication of abnormal physiology for assistance in catheter navigation. The catheter device may also include an actuator which uses the calibration to achieve homeostasis by fluxing fluids and/or guiding catheter movements.
28 Citations
16 Claims
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1. A computational catheter device, useful in association with a dynamic body system, the computational catheter device comprising:
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at least one fluid pathway; at least one pressure sensor configured to generate a pressure signal within an anatomical vessel for a dynamic body system; at least one external sensor configured to collect a fundamental frequency generated by at least one of a cardiovascular pulsation and external oscillator; a modeler configured to generate a predicted signal through the anatomical vessel using the collected fundamental frequency; and a spectral analyzer configured to generate a calibration by comparing the predicted signal to the pressure signal to identify obstructions within the anatomical vessel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for generating a calibration for a computational catheter device, useful in association with a dynamic body system, the method comprising:
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measuring a pressure signal within an anatomical vessel for a dynamic body system; measuring a fundamental frequency generated by at least one of a cardiovascular pulsation and external oscillator; generating a predicted signal through the anatomical vessel using the measured fundamental frequency; and generating a calibration by comparing the predicted signal to the pressure signal to identify obstructions within the anatomical vessel. - View Dependent Claims (12, 13, 14, 15, 16)
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Specification