Methods for scavenging nitric oxide using cerium oxide nanoparticles

• US 9,463,437 B2
• Filed: 02/14/2013
• Issued: 10/11/2016
• Est. Priority Date: 02/14/2013
• Status: Expired due to Fees

• Current Assignee: University of Central Florida Research Foundation Inc. (State University System of Florida)
• Original Assignee: University of Central Florida Research Foundation Inc. (State University System of Florida)
• Inventors: Self, William, Seal, Sudipta, Dowding, Janet
• Primary Examiner(s): Shomer, Isaac
• Application Number:
  US13/767,482
• Publication Number:
  US 20140227368A1
• Time in Patent Office: 1,335 Days
• US Class Current: 1/1
• CPC Class Codes: A61K 33/244 Lanthanides; Compounds thereof medicinal preparations containing radioactive lanthanides for use in therapy or testing in vivo A61K51/00
• CPC Class Codes: B01D 2253/1124 Metal oxides
• CPC Class Codes: B01D 2253/304 Linear dimensions, e.g. particle shape, diameter
• CPC Class Codes: B01D 2255/2065 Cerium
• CPC Class Codes: B01D 2255/9202 Linear dimensions
• CPC Class Codes: B01D 2257/404 Nitrogen oxides other than dinitrogen oxide
• CPC Class Codes: B01D 53/565 by treating the gases with solids
• CPC Class Codes: B01J 23/10 of rare earths
• CPC Class Codes: C02F 1/683 by addition of complex-forming compounds
• CPC Class Codes: C02F 1/70 by reduction C02F1/4676 takes precedence
• CPC Class Codes: Y10S 977/773 Nanoparticle, i.e. structure having three dimensions of 100 nm or less
• CPC Class Codes: Y10T 436/177692 Oxides of nitrogen

Abstract

The present invention includes a method for scavenging nitric oxide. The method includes contacting the nitric oxide with cerium oxide nanoparticles having a low 3+/4+ ratio.

Claims

1. A method for scavenging nitric oxide comprising contacting the nitric oxide with ceria nanoparticles comprising cerium in the 3+ and 4+ state and a low 3+/4+ ratio with decreased oxygen vacancies compared to ceria nanoparticles with a seventy-five (75) % 3+/4+ ratio, said ratios measured by x-ray photoelectron spectroscopy.

2. The method of claim 1, wherein the contacting is done within an exhaust stream from a combustion process.

3. The method of claim 1, wherein the contacting is done within a fluid stream following a wastewater treatment process.

4. The method of claim 1, wherein the contacting is done within a fluid following an etching or welding process.

5. The method of claim 1, wherein the low 3+/4+ ratio comprises 20±

5% 3+ cerium oxide nanoparticles.

6. The method of claim 1, wherein the contacting is done in vivo.