Mixing pen needle

• US 9,468,725 B2
• Filed: 04/24/2013
• Issued: 10/18/2016
• Est. Priority Date: 04/24/2013
• Status: Active Grant

• Current Assignee: Embecta Corporation
• Original Assignee: Becton, Dickinson & Co
• Inventors: West, Robert E.
• Primary Examiner(s): Bouchelle, Laura
• Assistant Examiner(s): Bui, Anh
• Application Number:
  US13/869,545
• Publication Number:
  US 20140323963A1
• Time in Patent Office: 1,273 Days
• US Class Current: 1/1
• CPC Class Codes: A61J 1/20 Arrangements for transferring or mixing fluids, e.g. from vial to syringe
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2027 having frangible parts
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2005/2451 preventing delivery before mixing is completed, e.g. by locking mechanisms
• CPC Class Codes: A61M 2005/2474 with movable piercing means, e.g. ampoule remains fixed or steady
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/2448 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3213 Caps placed axially onto the needle, e.g. equipped with finger protection guards axially-extensible protective sleeves A61M5/3243
• CPC Class Codes: A61M 5/3294 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/347 : rotatable, e.g. bayonet or screw A61M5/344 takes precedence

Abstract

An injection device is provided with dual medicament chambers and a mixing pen needle assembly, whereby predetermined dosages of two medicaments can be provided to a mixing reservoir in the pen needle assembly and delivered simultaneously with the injection device.

Claims

1. A method of mixing a medicament and delivering the medicament from a medication pen comprising:

selecting a first dose of a first medicament contained in a first medication compartment and selecting a second dose of a second medicament contained in a second medication compartment;

activating a first dosing mechanism by moving a first dosage plunger engaged in the first medication compartment delivering the first dose into a pen needle assembly received on the distal end of a movable housing, said pen needle assembly comprising a patient end needle, a filler needle, and an intermediate collapsible mixing reservoir;

wherein the collapsible mixing reservoir receives the first dose through the filler needle;

disengaging the first medication compartment from the collapsible mixing reservoir;

moving the movable housing and engaging the second medication compartment with the collapsible mixing reservoir;

activating a second dosing mechanism by moving a second dosage plunger engaged in the second medication compartment delivering the second dose into the collapsible mixing reservoir through the filler needle;

collapsing the mixing reservoir thereby forcing the first and second doses in the mixing reservoir through the patient end needle.

2. The method of claim 1, wherein the first and second medication compartments are positioned in a pen body connected to the movable housing by a shaft;

and

the collapsible mixing reservoir is disengaged from the first medication compartment by moving the movable housing and the shaft in a distal direction away from the first dosage plunger;

wherein the movable housing and the shaft are rotated to align the collapsible mixing reservoir with the second medication compartment; and

wherein the collapsible mixing reservoir is engaged with the second medication compartment by moving the movable housing and the shaft in a proximal direction toward the second dosage plunger.

3. The method of claim 2, wherein the pen needle assembly is threaded on an internally or externally threaded opening on the distal end of the movable housing.

4. The method of claim 1, including the steps of rotating a first dosage knob protruding from the proximal end of the medication pen to set the first dosage prior to activating the first dosing mechanism;

and rotating a second dosage knob protruding from the proximal end of the medication pen to set the second dose prior to activating the second dosing mechanism.

5. The method of claim 1, wherein the collapsible mixing reservoir includes a stopper moving within and sealing the mixing reservoir, and wherein a sleeve on the exterior of the pen needle assembly is secured to the stopper, so that moving the sleeve in a proximal direction moves the stopper to collapse the mixing reservoir, forcing medication out of the patient end needle.

6. The method of claim 1, wherein the first medicament is insulin and the second medicament is glucagon-like peptide.