Method and apparatus for electrotherapy drug delivery

• US 9,468,757 B2
• Filed: 06/03/2014
• Issued: 10/18/2016
• Est. Priority Date: 03/31/2005
• Status: Active Grant

• Current Assignee: Encore Medical Asset Corporation (Enovis Corp.)
• Original Assignee: Encore Medical Asset Corporation (Enovis Corp.)
• Inventors: Beck, Jon E., Hause, Robert F. Jr.
• Primary Examiner(s): OSINSKI, BRADLEY JAMES
• Application Number:
  US14/295,120
• Publication Number:
  US 20140288482A1
• Time in Patent Office: 868 Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
• CPC Class Codes: A61N 1/0436 Material of the electrode
• CPC Class Codes: A61N 1/30 Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

The present invention is directed to a method and apparatus for an electrotherapeutic system including a first and second electrode. Each electrode includes a respective resistance wherein during operation of the electrotherapeutic system, an electrochemical reaction involving one or both of the electrodes varies the respective resistance of at least one of the electrodes.

Claims

1. A drug delivery system, comprising:

a first electrode;

a second electrode;

a power source;

a power source connector operably coupled between the first electrode and the second electrode;

a first terminal operably connected to the power source connector;

a second terminal operably connected to the power source connector; and

a Z-axis conductive tape operably attached to the power source connector and configured to secure the power source, wherein the Z-axis conductive tape is exclusively electrically conductive in its Z-axis direction.

2. The drug delivery system of claim 1, wherein the Z-axis conductive tape is operably attached to the first terminal and the second terminal.

3. The drug delivery system of claim 1, further comprising a first conductor operably connected to the Z-axis conductive tape and the first terminal.

4. The drug delivery system of claim 3, wherein the conductor comprises a metallic tab, wherein the conductor is configured to retain the power source to the power source connector.

5. The drug delivery system of claim 3, further comprising a second conductor operably connected to the Z-axis conductive tape and the second terminal.

6. The drug delivery system of claim 5, wherein the second conductor and the second electrode are of a same metal composition.

7. The drug delivery system of claim 6, wherein the metal composition comprises Ag.

8. The drug delivery system of claim 6, wherein the metal composition comprises Ag/AgCl.

9. The drug delivery system of claim 5, wherein the first conductor, the first electrode, the second conductor, and the second electrode are of a same metal composition.

10. The drug delivery system of claim 9, wherein the metal composition comprises Ag.

11. The drug delivery system of claim 9, wherein the metal composition comprises Ag/AgCl.

12. The drug delivery system of claim 3, wherein the first conductor and the first electrode are of a same metal composition.

13. The drug delivery system of claim 12, wherein the metal composition comprises Ag.

14. The drug delivery system of claim 12, wherein the metal composition comprises Ag/AgCl.

15. The drug delivery system of claim 1, wherein the power source is configured to drive an electrolytic chemical reaction, wherein the first electrode has a resistance, wherein the second electrode has a resistance, and wherein during operation of the system, an electrolytic chemical reaction varies a respective resistance of at least one of the first electrode and the second electrode.

16. The drug delivery system of claim 1, further comprising:

a first hydratable matrix operably attached to the first electrode; and

a second hydratable matrix being operably attached to the second electrode.

17. The drug delivery system of claim 16, wherein either the first hydratable matrix or the second hydratable matrix comprises an ionic medicament.

18. The drug delivery system of claim 17, wherein the first hydratable matrix contains a first ionic solution;

wherein the second hydratable matrix contains a second ionic solution, and wherein during operation of the drug delivery system, an electrochemical reaction involving one or more members of the group consisting of the first electrode, the second electrode, the power source connector, the first terminal, and the second terminal, and one or more members of the group consisting of the first hydratable matrix , the second hydratable matrix, the first ionic solution, and the second ionic solution varies a respective resistance of at least one member of the group consisting of the first electrode and the second electrode.

19. The drug delivery system of claim 16, wherein either the first hydratable matrix or the second hydratable matrix comprises a non-drug ionic electrolyte.

20. The drug delivery system of claim 1, wherein the power source is a battery.

21. The drug delivery system of claim 1, wherein the power source is an electrochemical storage device.

22. The drug delivery system of claim 1, wherein the power source comprises an electrical generator and/or an electrostatic storage device.

23. The drug delivery system of claim 1, further comprising a current regulator operably connected between the power source connector and either the first electrode or the second electrode.

24. The drug delivery system of claim 23, wherein the current regulator is a resistor.

25. The drug delivery system of claim 24, wherein the resistor is printed.

26. The drug delivery system of claim 24, wherein the resistor is a discrete component.

27. The drug delivery system of claim 24, wherein a value of the resistor is selected in response to a power source voltage, a maximum required current, or an application of the drug delivery system.

28. The drug delivery system of claim 1, further comprising a housing.