Diagnostic radio frequency identification sensors and applications thereof
First Claim
1. A Lab-on-a-Chip microfluidics sensor system for use in conducting rapid diagnostic measurements comprising:
- a Lab-On-A-Chip (LOC) microfluidics sensor test strip comprising a substrate containing a plurality of wells and a plurality of microfluidics channels, said channels permitting a flow of fluids between said wells;
a radio frequency identification (RFID) tag comprising an antenna, a unique identification number, and an RFID electronic chip in combination with at least one sensor module and both integrated with said substrate, with a plurality of conductive leads connecting said RFID electronic chip and said sensor module to said wells and said channels, and said RFID tag and said sensor module combination configured to sense, control and transmit wirelessly signals that correspond to reactions occurring in said wells and to transmit wirelessly said unique identification number;
a wireless reader configured to communicate wirelessly with said RFID tag and said sensor module combination through the use of multiple protocols and to receive said signals that correspond to said reactions occurring in said wells and said unique identification number, said wireless reader configured to control a flow of fluids through said microfluidics channels and to and from said wells by sending signals to said REID tag and said sensor module combination wirelessly; and
said wireless reader further configured to communicate wirelessly over a network through the use of multiple communication protocols to download software wirelessly from a remote location to enable reading and analysis of said signals received from said RFID tag and said sensor module combination based on said unique identification number of said RFID tag and sensor module combination.
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Accused Products
Abstract
An integrated passive wireless chip diagnostic sensor system is described that can be interrogated remotely with a wireless device such as a modified cell phone incorporating multi-protocol RFID reader capabilities (such as the emerging Gen-2 standard) or Bluetooth, providing universal easy to use, low cost and immediate quantitative analyses, geolocation and sensor networking capabilities to users of the technology. The present invention can be integrated into various diagnostic platforms and is applicable for use with low power sensors such as thin films, MEMS, electrochemical, thermal, resistive, nano or microfluidic sensor technologies. Applications of the present invention include on-the-spot medical and self-diagnostics on smart skin patches, Point-of-Care (POC) analyses, food diagnostics, pathogen detection, disease-specific wireless biomarker detection, remote structural stresses detection and sensor networks for industrial or Homeland Security using low cost wireless devices such as modified cell phones.
84 Citations
17 Claims
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1. A Lab-on-a-Chip microfluidics sensor system for use in conducting rapid diagnostic measurements comprising:
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a Lab-On-A-Chip (LOC) microfluidics sensor test strip comprising a substrate containing a plurality of wells and a plurality of microfluidics channels, said channels permitting a flow of fluids between said wells; a radio frequency identification (RFID) tag comprising an antenna, a unique identification number, and an RFID electronic chip in combination with at least one sensor module and both integrated with said substrate, with a plurality of conductive leads connecting said RFID electronic chip and said sensor module to said wells and said channels, and said RFID tag and said sensor module combination configured to sense, control and transmit wirelessly signals that correspond to reactions occurring in said wells and to transmit wirelessly said unique identification number; a wireless reader configured to communicate wirelessly with said RFID tag and said sensor module combination through the use of multiple protocols and to receive said signals that correspond to said reactions occurring in said wells and said unique identification number, said wireless reader configured to control a flow of fluids through said microfluidics channels and to and from said wells by sending signals to said REID tag and said sensor module combination wirelessly; and said wireless reader further configured to communicate wirelessly over a network through the use of multiple communication protocols to download software wirelessly from a remote location to enable reading and analysis of said signals received from said RFID tag and said sensor module combination based on said unique identification number of said RFID tag and sensor module combination. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification