Method for diagnosis and treatment of disorders of the gastrointestinal tract, and apparatus for use therewith

• US 9,474,482 B2
• Filed: 11/01/2011
• Issued: 10/25/2016
• Est. Priority Date: 11/01/2010
• Status: Active Grant

• Current Assignee: G-Technology
• Original Assignee: G-Tech Medical Inc.
• Inventors: Devanaboyina, Udaya Sankar
• Primary Examiner(s): Thomson, William
• Assistant Examiner(s): Archer, Marie
• Application Number:
  US13/373,042
• Publication Number:
  US 20130046150A1
• Time in Patent Office: 1,820 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 2562/164 the sensor is mounted in or on a conformable substrate or carrier
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/0024 for multiple sensor units attached to the patient, e.g. using a body or personal area network
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/1123 Discriminating type of movement, e.g. walking or running A61B5/1116, A61B5/112 take precedence
• CPC Class Codes: A61B 5/296 for electromyography [EMG]
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/392 Detecting gastrointestinal contractions
• CPC Class Codes: A61B 5/42 Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence
• CPC Class Codes: A61B 5/4205 Evaluating swallowing
• CPC Class Codes: A61B 5/4211 Diagnosing or evaluating reflux
• CPC Class Codes: A61B 5/6823 Trunk, e.g., chest, back, abdomen, hip
• CPC Class Codes: A61B 5/6831 Straps, bands or harnesses
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: G16H 10/65 stored on portable record carriers, e.g. on smartcards, RFID tags or CD
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/20 : for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A method for diagnosing motility disorders of a gastrointestinal tract of a body. The method can include measuring electrical signals from the gastrointestinal tract while the patient is engaged in normal daily activities, recording the measured electrical signals on a portable electronic device carried by the body, recording by the patient in real time one or more symptoms of the body and analyzing characteristics of the recorded electrical signals with the recorded symptoms of the body to diagnosis gastrointestinal disorders of the body. Apparatus for use therewith and methods for treatment thereof are provided.

Claims

1. A method for facilitating diagnosis of motility disorders of a gastrointestinal tract of a body of a patient, the method performed by a portable electronic device carried by the body and wirelessly connected to a plurality of external electrodes, the method comprising:

acquiring, by the portable electronic device, electrical signals from the plurality of wirelessly connected external electrodes while the patient is engaged in normal daily activities, wherein the electrical signals include electromyography signals concurrently acquired from a plurality of organs of the gastrointestinal tract, wherein the organs include a stomach, small intestines, and large intestines, wherein each of the organs produces a separate electromyography signal, and wherein the electrical signals are acquired from external electrodes positioned in a circular pattern on the skin of the body over the patient'"'"'s abdomen;

recording the acquired electrical signals to memory on the portable electronic device;

processing, by a processor of the portable electronic device, the acquired electrical signals to generate a plurality of processed waveforms;

recording, to memory on the portable electronic device, one or more inputs entered by the patient for one or more symptoms of the body selected from a group consisting of;

bowel movements, cramping, bloating, vomiting, nausea, heartburn, pain from chest, abdomen, or pelvic regions, refluxing, incontinence, constipation, stool form, and symptoms relating to esophageal motility disorders, incontinence, or other gastrointestinal disorder;

correlating, by the processor, the processed waveforms to the patient-entered symptoms based on time;

identifying, by the processor, a plurality of characteristics of the processed waveforms, wherein the characteristics of the processed waveforms are selected from a group consisting of;

frequency, amplitude, power, pattern, duration, and periodicity;

identifying, by the processor, the respective organ associated with each processed waveform and the organs that experienced electrical activity during a duration of time, based on the plurality of characteristics of the processed waveforms;

characterizing, by the processor, the processed waveforms as being indicative of normal or abnormal activity of the organs based on the plurality of characteristics of the processed waveforms; and

outputting, from the processor to a display, an alert indicative of a status of normal or abnormal activity of the organs.

2. The method of claim 1, further comprising wirelessly transmitting information stored in the portable electronic device to a remote monitoring center.

3. The method of claim 1, further comprising acquiring and recording, by the portable electronic device, electrical signals from sensors on the head of the body by means of electroencephalography.

4. The method of claim 1, further comprising acquiring and recording, by the portable electronic device, electrical signals from sensors placed over skeletal muscles in the abdomen and pelvic regions of the body by means of electromyography.

5. The method of claim 1, further comprising acquiring and recording, by the portable electronic device, conductance of the skin of the body measured by conductance sensors positioned on the skin.

6. The method of claim 1, further comprising acquiring and recording, by the portable electronic device, cardiac electrical signals from sensors positioned on a chest of the body by means of electrocardiography.

7. The method of claim 1, further comprising acquiring and recording, by the portable electronic device, respiratory signals while the patient is engaged in daily activities.

8. The method of claim 1, further comprising acquiring and recording, by the portable electronic device, motion of the body.

9. The method of claim 1, further comprising recording data entered by the patient indicative of one or more events of the body selected from a group consisting of eating, inking, bowel movement, emesis, walking, jogging, traveling in a vehicle, and sitting.

10. The method of claim 1, wherein recording the acquired electrical signals comprises recording sequential propagation of electrical activity from a plurality of segments of the gastrointestinal tract.

11. The method of claim 1, wherein the one or more inputs entered by the patient are recorded with a time stamp.

12. The method of claim 1, wherein the electrical signals are recorded for a period ranging from one minute to seven days.