Tissue marking implant

• US 9,480,554 B2
• Filed: 05/18/2015
• Issued: 11/01/2016
• Est. Priority Date: 10/10/1997
• Status: Expired due to Fees

• Current Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Original Assignee: Senorx Incorporated (Becton, Dickinson & Co)
• Inventors: Corbitt, John D. Jr.
• Primary Examiner(s): Gherbi, Suzette J
• Application Number:
  US14/714,748
• Publication Number:
  US 20150257872A1
• Time in Patent Office: 533 Days
• Field of Search: 623 7- 8
• US Class Current: 1/1
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61F 2/0059 Cosmetic or alloplastic implants A61F2/10 - A61F2/16, A61F2/28 take precedence
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/12 Mammary prostheses and implants
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0066 shrinkable
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/36 containing ingredients of undetermined constitution or reaction products thereof , e.g. transplant tissue, natural bone, extracellular matrix isolated natural compounds, e.g. collagen A61L27/24
• CPC Class Codes: A61L 27/56 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 27/58 Materials at least partially resorbable by the body
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence

Abstract

A method for marking a surgically formed cavity in a patient includes providing an implant comprising a matrix material and a marking material, the matrix material configured to be elastically compressible; modifying the shape and size of the implant to fit the shape and size of the surgically formed cavity in the patient, the implant being configured to fill the surgically formed cavity and support tissue surrounding the surgically formed cavity and to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material; and inserting the implant into the surgically formed cavity.

Claims

1. A method for marking a surgically formed cavity in a patient, comprising:

providing an implant comprising a matrix material and a marking material, the matrix material configured to be elastically compressible;

modifying the shape and size of the implant to fit the shape and size of the surgically formed cavity in the patient, the implant being configured to fill the surgically formed cavity and support tissue surrounding the surgically formed cavity and to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material; and

inserting the implant into the surgically formed cavity.

2. The method of claim 1, comprising inserting a dye into the matrix material.

3. The method of claim 1, wherein the matrix material comprises one of a foam or sponge, and is at least partially resorbable.

4. The method of claim 1, wherein the matrix material comprises a foamed bioabsorbable protein.

5. The method of claim 1, wherein the matrix material comprises of a foamed collagen.

6. The method of claim 1, comprising inserting at least one medicinal, therapeutic, or diagnostic substance into the matrix material.

7. The method of claim 6, wherein the at least one medicinal, therapeutic, or diagnostic substance is selected from the group consisting of radiation materials, antibiotics, chemotherapies, cancer therapeutics, hemostatic materials, hormone therapeutics, and radiographic markers.

8. The method of claim 1, comprising surrounding the matrix material with a shell.

9. The method of claim 8, wherein the shell comprises a compressed matrix material.

10. A method for forming an implant for marking a surgically formed cavity in a patient, comprising:

providing a matrix material and a marking material to form an implant, the matrix material configured to be elastically compressible; and

modifying the shape and size of the implant to fit the shape and size of the surgically formed cavity in the patient, the implant being configured to fill the surgically formed cavity and support tissue surrounding the surgically formed cavity and to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material.

11. The method of claim 10, comprising inserting a dye into the matrix material.

12. The method of claim 10, wherein the matrix material comprises one of a foam or sponge, and is at least partially resorbable.

13. The method of claim 10, wherein the matrix material comprises a foamed bioabsorbable protein.

14. The method of claim 10, wherein the matrix material comprises of a foamed collagen.

15. The method of claim 10, comprising inserting at least one medicinal, therapeutic, or diagnostic substance into the matrix material.

16. The method of claim 15, wherein the at least one medicinal, therapeutic, or diagnostic substance is selected from the group consisting of radiation materials, antibiotics, chemotherapies, cancer therapeutics, hemostatic materials, hormone therapeutics, and radiographic markers.

17. The method of claim 10, comprising surrounding the matrix material with a shell.

18. The method of claim 17, wherein the shell comprises a compressed matrix material.

19. A method of operating a marker delivery device for marking a surgically formed cavity in a patient, comprising:

providing a delivery cannula having a distal discharge opening;

providing an implant comprising a matrix material and a marking material, the matrix material being configured to be elastically compressible and configured to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material after implantation in the surgically formed cavity;

forming the implant to a shape and a size of the surgically formed cavity to fill the surgically formed cavity and support tissue surrounding the surgically formed cavity;

compressing the implant to fit within the delivery cannula;

inserting the delivery cannula into the patient until the distal discharge opening of the delivery cannula is located within the surgically formed cavity; and

discharging the implant from the delivery cannula through the distal discharge opening, wherein the matrix material expands such that the implant fills the surgically formed cavity.

20. The method of claim 19, comprising surrounding the matrix material with a shell.