Expanding ocular implant devices and methods

• US 9,480,598 B2
• Filed: 09/17/2013
• Issued: 11/01/2016
• Est. Priority Date: 09/17/2012
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Novartis Ag
• Inventors: Clauson, Luke, Schaller, Michael, Lari, David
• Primary Examiner(s): Deak, Leslie
• Application Number:
  US14/029,389
• Publication Number:
  US 20140081195A1
• Time in Patent Office: 1,141 Days
• Field of Search: 604/8, 623/1.2, 623/1.29
• US Class Current: 1/1
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2250/001 for adjusting a diameter
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Disclosed herein are devices and methods related to implants for treating one or more physiological conditions of the eye. Some embodiments disclosed herein include an expandable ocular implant for implanting in an eye. The expandable implant can include an implant having an elongate tubular body and an expandable sheath securely adapted to a part of the implant. Some embodiments of the expandable sheath can have at least one expandable feature that can assist the expandable sheath in forming a compact and an expanded configuration.

Claims

1. A device for implanting in an eye, comprising:

an expandable sheath formed of an elongate, tubular body having at least one expandable feature configured to form an expanded and a compact configuration, the at least one expandable feature including at least two longitudinal, non-intersecting struts each extending from a proximal collar to a distal collar, and wherein the at least one of the proximal collar and distal collar is adaptable to an ocular implant, wherein the implant includes a second elongate tubular body configured to be implanted in an eye and wherein at least one of the proximal collar and the distal collar is fixedly attached to the second tubular body of the device and the other of the proximal collar and the distal collar is movably attached to the second tubular body of the device such that the distal collar slides co-axially along a longitudinal axis of the second tubular body.

2. The device of claim 1, wherein at least the expandable features are made out of a medical grade shape memory material, such as nitinol or a shape memory polymer.

3. The device of claim 1, wherein the expandable sheath is formed out of a laser cut nitinol material.

4. The device of claim 1, wherein at least a part of a surface of the expandable sheath is treated with a plasma cleaning process.

5. The device of claim 1, wherein at least a part of a surface of the expandable sheath is treated with a laser ablation process.

6. The device of claim 5, wherein the surface treated with the laser ablation process includes at least one ribbed feature.

7. The device of claim 1, wherein the compact configuration has an outside diameter dimension in the range of 0.4 millimeter to 0.6 millimeter.

8. The device of claim 1, wherein the expanded configuration has an outside diameter dimension in the range of 2.0 millimeters to 3.0 millimeters.

9. The device of claim 1, wherein the expandable sheath includes at least one drug.

10. The device of claim 9, wherein the expandable sheath is adapted to an implant that does not include a drug.

11. A method, comprising:

providing an expandable sheath, wherein the expandable sheath includes at least one expandable feature configured to form an expanded and a compact configuration, the at least one expandable feature including at least two longitudinal, non-intersecting struts each extending from at least one of a proximal collar and a distal collar, and wherein the at least one of the proximal collar and distal collar is configured to attach to an ocular implant;

attaching the expandable sheath to the implant;

implanting the implant and the expandable sheath into an eye

sliding at least one of the proximal collar and distal collar co-axially along a longitudinal axis of the expandable sheath to expand the struts.

12. The method of claim 11, wherein the at least one expandable feature is in a compact configuration during implantation of the expandable sheath and forms an expanded configuration after implantation into the eye.

13. The method of claim 11, wherein the implant includes an elongate tubular body configured to be implanted in an eye.

14. The method of claim 11, wherein at least the expandable features are made out of a medical grade shape memory material, such as nitinol or a shape memory polymer.

15. The method of claim 11, wherein the expandable sheath is formed out of a laser cut nitinol material.

16. The method of claim 11, wherein at least a part of a surface of the expandable sheath is treated with a plasma cleaning process.

17. The method of claim 11, wherein at least a part of a surface of the expandable sheath is treated with a laser ablation process.

18. The method of claim 17, wherein the surface treated with the laser ablation process includes at least one ribbed feature.

19. The device of claim 11, wherein the expandable sheath includes at least one drug.

20. The device of claim 19, wherein the expandable sheath is adapted to an implant that does not include a drug.