×

Method of inhibiting mutant C-kit

  • US 9,480,683 B2
  • Filed: 09/13/2013
  • Issued: 11/01/2016
  • Est. Priority Date: 09/26/2012
  • Status: Active Grant
First Claim
Patent Images

1. A method of inhibiting or reducing mutant C-KIT tyrosine kinase activity or expression in a subject having or suspected of having a proliferative disease positive for a constitutively active mutant C-KIT, comprised of identifying the subject having a proliferative disease positive for a constitutively active mutant C-KIT, wherein the C-KIT mutant is at least one of C-KIT D816, D816F, D816H, D816N, D816Y and D816V, and administering to the subject a therapeutically effective amount of the compound of Formula I:

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×