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Mineralization and biological modification of biomaterial surfaces

  • US 9,480,773 B2
  • Filed: 05/28/2015
  • Issued: 11/01/2016
  • Est. Priority Date: 03/19/1999
  • Status: Expired due to Fees
First Claim
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1. A method for controlling mineralization of a biomaterial surface, comprising:

  • (a) functionalizing at least a first surface of a biomaterial; and

    (b) contacting the functionalized biomaterial surface with an amount of a mineral-containing solution effective to form a mineralized biomaterial,wherein(i) the mineralized biomaterial comprises an extended, mineral coating at the functionalized biomaterial surface and is degradable over a controllable time scale; and

    (ii) the biomaterial comprises at least a first porous, biodegradable polymer portion having an interconnected pore structure and further comprises at least a first portion that is prepared by a process comprising heating a biodegradable polymer.

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