Vital information measurement device and vital information measurement method employing same

• US 9,482,636 B2
• Filed: 10/26/2011
• Issued: 11/01/2016
• Est. Priority Date: 10/28/2010
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Inventors: Yoshioka, Eriko, Tokunaga, Hiroyuki
• Primary Examiner(s): Van, Luan
• Assistant Examiner(s): Rosenwald, Steven
• Application Number:
  US13/824,078
• Publication Number:
  US 20130204108A1
• Time in Patent Office: 1,833 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/26 by investigating electrochemical variables; by using electrolysis or electrophoresis
• CPC Class Codes: G01N 27/28 Electrolytic cell components
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: G01N 27/416 Systems G01N27/27 takes precedence

Abstract

An objective of the present invention is to provide a vital information measurement device which measures vital information using a biosensor, with which it is possible to adjudicate more precisely whether a mounted biosensor is usable, and to alleviate inconsistency in measured values therefrom. Specifically, the present invention provides a vital information measurement device comprising: an input terminal to which a biosensor is connected; a voltage application unit which applies a voltage to the input terminal; an adjudication unit which is connected to the input terminal; a control unit which is connected to the adjudication unit; and a display unit which is connected to the control unit. The control unit causes the adjudication unit to carry out a first adjudication, a second adjudication, and a third adjudication.

Claims

1. A vital information measurement device comprising an input terminal to which a biosensor is connected, a voltage application section that applies voltage to the input terminal, a measurement section that measures a measurement value based on a value of electric current flowing in the biosensor, a determination section, a control section, and a display, wherein:

the measurement section is configured to measure a first measurement value and a second measurement value based on the value of the electric current flowing in the biosensor when the voltage application section applies voltage to the biosensor connected to the input terminal through the input terminal before a biological sample is supplied to the biosensor, and the second measurement value is a value measured after the first measurement value is measured; and

the control section is configured to cause the determination section to perform a first determination, a second determination and a third determination, to determine whether the biosensor is usable based on results of the first, second, and third determinations before the biological sample is supplied to the biosensor, wherein;

the first measurement value or the second measurement value is compared with a first threshold value, in the first determination,

the first measurement value is compared with a second threshold value, in the second determination,

a difference X between the first measurement value and the second measurement value is compared with a third threshold value, in the third determination, and

the first threshold value is larger than the second threshold value, and the second threshold value is larger than the third threshold value.

2. The vital information measurement device according to claim 1, wherein:

the measurement section measures the second measurement value for a plurality of times; and

the maximum difference among the plurality of differences X between the first measurement value and each of the second measurement values is compared with the third threshold value, in the third determination.

3. The vital information measurement device according to claim 1, wherein:

in a case where the first measurement value or the second measurement value is equal to or larger than the first threshold value in the first determination, the control section displays information indicating that the biosensor is unusable on the display section.

4. The vital information measurement device according to claim 1, wherein:

in a case where the first measurement value is equal to or larger than the second threshold value in the second determination, the control section causes the determination section to perform the third determination.

5. The vital information measurement device according to claim 1, wherein:

in a case where the difference X is smaller than the third threshold value in the third determination, the control section displays information indicating that the biosensor is unusable on the display.

18. The vital information measurement device according to any one of claims 1, 6 and 12, wherein:

the input terminal is connected with the determination section via a current-voltage converter section and an A/D converter section from the input terminal.

6. A vital information measurement device comprising an input terminal to which a biosensor is connected, a voltage application section that applies voltage to the input terminal, a measurement section that measures a measurement value based on a value of electric current flowing in the biosensor, a determination section, a control section, and a display, wherein:

the measurement section is configured to measure a first measurement value and a second measurement value based on the value of the electric current flowing in the biosensor when the voltage application section applies voltage to the biosensor connected to the input terminal through the input terminal before a biological sample is supplied to the biosensor, and the second measurement value is a value measured after the first measurement value is measured; and

the control section is configured to cause the determination section to perform a first determination, a second determination and a third determination, to determine whether the biosensor is usable based on results of the first, second, and third determinations before the biological sample is supplied to the biosensor, wherein;

the first measurement value or the second measurement value is compared with a first threshold value, in the first determination,

the second measurement value is compared with a second threshold value, in the second determination,

a difference X between the first measurement value and the second measurement value is compared with a third threshold value, in the third determination, and

the first threshold value is larger than the second threshold value, and the second threshold value is larger than the third threshold value.

7. The vital information measurement device according to claim 6, wherein:

the measurement section measures the second measurement value for a plurality of times; and

the maximum difference among the plurality of differences X between the first measurement value and each of the second measurement values is compared with the third threshold value, in the third determination.

8. The vital information measurement device according to claim 6, wherein:

in a case where the first measurement value or the second measurement value is equal to or larger than the first threshold value in the first determination, the control section displays information indicating that the biosensor is unusable on the display section.

9. The vital information measurement device according to claim 6, wherein:

in a case where the second measurement value is equal to or larger than the second threshold value in the second determination, the control section causes the determination section to perform the third determination.

10. The vital information measurement device according to claim 6, wherein:

in a case where the difference X is smaller than the third threshold value in the third determination, the control section displays information indicating that the biosensor is unusable on the display section.

11. A vital information measurement device comprising an input terminal to which a biosensor is connected, a voltage application section that applies voltage to the input terminal, a measurement section that measures a measurement value based on a value of electric current flowing in the biosensor, a determination section, a control section, and a display, wherein:

the measurement section is configured to measure a first measurement value and a second measurement value based on the value of the electric current flowing in the biosensor when the voltage application section applies voltage to the biosensor connected to the input terminal through the input terminal before a biological sample is supplied to the biosensor, and the second measurement value is a value measured after the first measurement value is measured; and

the control section is configured to cause the determination section to perform a determination of comparing a difference X between the first measurement value and the second measurement value with a threshold value, to determine whether the biosensor is usable based on results of the first, second, and third determinations before the biological sample is supplied to the biosensor, and the first threshold value is larger than the second threshold value, and the second threshold value is larger than the third threshold value.

12. A vital information measurement device comprising an input terminal to which a biosensor is connected, a voltage application section that applies voltage to the input terminal, a measurement section that measures a measurement value based on a value of electric current flowing in the biosensor, a determination section, a control section, and a display, wherein:

the measurement section is configured to measure a first measurement value, a second measurement value and a third measurement value based on the value of the electric current flowing in the biosensor when the voltage application section applies voltage to the biosensor connected to the input terminal through the input terminal before a biological sample is supplied to the sensor, and the second measurement value is a value measured after the first measurement value is measured and the third measurement value is a value measured after the second measurement value is measured; and

the control section is configured to cause the determination section to perform a first determination, a second determination and a third determination, to determine whether the biosensor is usable based on results of the first, second, and third determinations before the biological sample is supplied to the biosensor, wherein;

the first measurement value or the second measurement value is compared with a first threshold value, in the first determination,

the first measurement value or the second measurement value is compared with a second threshold value, in the second determination,

a difference Y between the first measurement value and the third measurement value or a difference Z between the second measurement value and the third measurement value is compared with a third threshold value, in the third determination, and

the first threshold value is larger than the second threshold value, and the second threshold value is larger than the third threshold value.

13. The vital information measurement device according to claim 12, wherein:

the measurement section measures the third measurement value for a plurality of times; and

the maximum difference among the plurality of differences Y between the first measurement value and each of the third measurement values or the maximum difference among the plurality of differences Z between the second measurement value and each of the third measurement values is compared with the third threshold value, in the third determination.

14. The vital information measurement device according to claim 12, wherein:

in a case where the first measurement value or the second measurement value is equal to or larger than the first threshold value in the first determination, the control section displays information indicating that the biosensor is unusable on the display.

15. The vital information measurement device according to claim 12, wherein:

in a case where the first measurement value or the second measurement value is equal to or larger than the second threshold value in the second determination, the control section causes the determination section to perform the third determination.

16. The vital information measurement device according to claim 12, wherein:

in a case where the difference Y or the difference Z is smaller than the third threshold value in the third determination, the control section displays information indicating that the biosensor is unusable on the display section.

17. A vital information measurement device comprising an input terminal to which a biosensor is connected, a voltage application section that applies voltage to the input terminal, a measurement section that measures a measurement value based on a value of electric current flowing in the biosensor, a determination section, a control section, and a display, wherein:

the measurement section is configured to measure a first measurement value, a second measurement value and a third measurement value based on the value of the electric current flowing in the biosensor when the voltage application section applies voltage to the biosensor connected to the input terminal through the input terminal before a biological sample is supplied to the biosensor, and the second measurement value is a value measured after the first measurement value is measured and the third measurement value is a value measured after the second measurement value is measured; and

the control section is configured to cause the determination section to perform a determination of comparing a difference Y between the first measurement value and the third measurement value or a difference Z between the second measurement value and the third measurement value with a threshold value, to determine whether the biosensor is usable based on results of the first, second, and third determinations before the biological sample is supplied to the biosensor, and the first threshold value is larger than the second threshold value, and the second threshold value is larger than the third threshold value.