Predictive calibration
First Claim
1. A method of operating a portable medical monitor system that generates an estimate of an analyte level of a patient being monitored with an analyte sensor, the method comprising:
- generating a current calibration curve for generating the estimate of the analyte level being monitored, wherein the current calibration curve is based on at least two measured data values of the level being monitored;
determining a transformation function based on the current calibration curve and at least one preceding calibration curve such that the transformation function produces a predictive calibration curve that predicts changes to the current calibration curve resulting from sensor drift since the acquisition of the at least two measured data values used to generate the current calibration curve;
generating an estimated level value of the analyte level being monitored, based on sensor output from the analyte sensor, in accordance with the predictive calibration curve; and
causing medicament to be delivered to the patient with a portable infusion pump based on the estimated level value of the analyte being monitored.
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Accused Products
Abstract
A portable medical monitor system generates a current calibration curve for generating the estimate of the level of an analyte, such as glucose, being monitored. The current calibration curve is based on at least two measured data values of the level being monitored. The system determines a transformation function based on the calibration curve and at least one preceding calibration curve such that the transformation function produces a predictive calibration curve, and generates an estimated level value of the level being monitored, based on sensor output from a sensor associated with the portable medical monitor system, in accordance with the predictive calibration curve.
132 Citations
30 Claims
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1. A method of operating a portable medical monitor system that generates an estimate of an analyte level of a patient being monitored with an analyte sensor, the method comprising:
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generating a current calibration curve for generating the estimate of the analyte level being monitored, wherein the current calibration curve is based on at least two measured data values of the level being monitored; determining a transformation function based on the current calibration curve and at least one preceding calibration curve such that the transformation function produces a predictive calibration curve that predicts changes to the current calibration curve resulting from sensor drift since the acquisition of the at least two measured data values used to generate the current calibration curve; generating an estimated level value of the analyte level being monitored, based on sensor output from the analyte sensor, in accordance with the predictive calibration curve; and causing medicament to be delivered to the patient with a portable infusion pump based on the estimated level value of the analyte being monitored. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 15)
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12. A portable medical monitor system comprising:
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an analyte sensor that provides a sensor output value; a control processor that receives the sensor output value, wherein the processor is configured to execute program instructions stored in memory of the portable medical monitor system to generate a current calibration curve based on at least two measured values of an analyte level of a patient being monitored, to determine a transformation function based on the current calibration curve and at least one preceding calibration curve such that the transformation function produces a predictive calibration curve that predicts changes to the current calibration curve resulting from sensor drift since the acquisition of the at least two measured values used to generate the current calibration curve, and to generate an estimated analyte level value of the analyte being monitored, based on the sensor output value, in accordance with the predictive calibration curve, and wherein the controller processor is further configured to cause medicament to be delivered to the patient with a portable infusion pump based on the estimated level value of the analyte being monitored. - View Dependent Claims (13, 14, 16, 17, 18, 19, 20, 21)
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22. A method of configuring a portable medical monitor system, the method comprising:
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establishing a network communication link at a server computer to the portable medical monitor system; transmitting program instructions from the server computer to the portable medical monitor system over the network communication link, wherein the transmitted program instructions are configured to be stored in memory of the portable medical monitor system and executed to receive a sensor output value of an analyte sensor and generate a current calibration curve based on at least two measured values of an analyte level of a patient being monitored, to determine a transformation function based on the current calibration curve and at least one preceding calibration curve such that the transformation function produces a predictive calibration curve that predicts changes to the current calibration curve resulting from sensor drift since the acquisition of the at least two measured data values used to generate the current calibration curve, and to generate an estimated analyte level value of the analyte being monitored, based on the sensor output level, in accordance with the predictive calibration curve; and causing medicament to be delivered to the patient with a portable infusion pump based on the estimated level value of the analyte being monitored. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30)
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Specification