Prosthesis having a plurality of distal and proximal prongs

• US 9,486,336 B2
• Filed: 01/22/2013
• Issued: 11/08/2016
• Est. Priority Date: 11/10/2005
• Status: Active Grant

• Current Assignee: Edwards Lifesciences CardiAQ LLC (Edwards Lifesciences Corporation)
• Original Assignee: Edwards Lifesciences CardiAQ LLC (Edwards Lifesciences Corporation)
• Inventors: Quadri, Arshad
• Primary Examiner(s): Sweet, Thomas J
• Assistant Examiner(s): Wolf, Megan
• Application Number:
  US13/747,270
• Publication Number:
  US 20130138203A1
• Time in Patent Office: 1,386 Days
• Field of Search: 623/1.15, 623/1.16, 623/1.36
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

A prosthesis can be deployed within a body cavity. The prosthesis can include an expandable frame, a plurality of proximal prongs, and a plurality of distal prongs. Each prong of the proximal and distal pluralities is connected to the frame. When the frame is expanded, the ends of the prongs are positioned radially outward from the frame. The frame is configured such that radial expansion of the frame causes the ends of the proximal prongs and the ends of the distal prongs to draw closer together.

Claims

1. A prosthesis configured to be deployed within a native heart valve comprising an opening surrounded by surrounding body tissue of the native heart valve, the surrounding body tissue having a first side and a second side opposite the first side, the prosthesis comprising:

an expandable frame comprising a proximal end and a distal end and a longitudinal axis extending therethrough, the expandable frame comprising a plurality of cells configured to permit the frame to radially expand and collapse for deployment within an opening of the native heart valve, wherein the cells have a generally diamond shape with four vertices when the frame is in an expanded configuration, wherein the frame comprises a laser-cut metal tube;

a valve seated inside the expandable frame;

a plurality of proximal anchors each connected to the frame so that when the frame is in an expanded configuration within the opening of the native heart valve, an anchoring portion of each proximal anchor extends distally to a distalmost portion of the proximal anchor that is positioned radially outward from the frame; and

a plurality of distal anchors each connected to the frame and so that when the frame is in an expanded configuration within the opening of the native heart valve, an anchoring portion of each distal anchor extends proximally to a proximalmost portion of the distal anchor that is positioned radially outward from the frame;

wherein when the frame is in an expanded configuration, at least some of the anchoring portions of at least one of the pluralities of proximal anchors and distal anchors connect to one of the vertices of a generally diamond-shaped cell and curve radially outward before extending respectively, distally or proximally, in an axial direction approximately parallel with each other and with the longitudinal axis;

wherein, when the frame is in an expanded configuration, distalmost portions of the plurality of proximal anchors and proximalmost portions of the plurality of distal anchors are spaced apart by less than two cell lengths; and

wherein the frame, the plurality of proximal anchors, and the plurality of distal anchors are sized and configured such that radial expansion of the frame causes the proximal anchors and the distal anchors to draw closer together and pinch the first side of the surrounding body tissue of the native heart valve and the second side of the surrounding body tissue of the native heart valve towards each other.

2. The prosthesis of claim 1, wherein the proximal anchors are connected to the frame only at locations on the frame proximal to the distalmost portions.

3. The prosthesis of claim 1, wherein the distal anchors are connected to the frame only at locations on the frame distal to the proximalmost portions.

4. The prosthesis of claim 1, wherein the distal anchors extend from distalmost vertices of cells of the frame.

5. The prosthesis of claim 1, wherein the frame is configured such that if the expandable frame is moved proximally or distally within the opening, the proximalmost or distalmost portions of at least some of the anchoring portions engage surrounding body tissue with a longitudinal force applied perpendicular to a surface of the surrounding body tissue.

6. The prosthesis of claim 1, wherein the proximal anchors and the distal anchors are arranged in pairs, wherein ends of the anchors of each pair are generally collinear.

7. The prosthesis of claim 1, wherein the frame comprises a material capable of self-expansion.

8. The prosthesis of claim 1, wherein the plurality of proximal anchors, the plurality of distal anchors and the frame are laser-cut.

9. The prosthesis of claim 1, wherein when the frame is in an expanded configuration, at least some of the anchoring portions of at least one of the pluralities of proximal anchors and distal anchors extend distally or proximally, respectively, in an axial direction approximately parallel with each other and with the longitudinal axis over a substantial portion of the longitudinal length of one cell of the expandable frame.