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Regulation of food preference using GLP-1 agonists

  • US 9,486,504 B2
  • Filed: 05/12/2010
  • Issued: 11/08/2016
  • Est. Priority Date: 12/09/2003
  • Status: Expired due to Fees
First Claim
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1. A method for shifting food preference in a subject with an abnormal or excessive intake of food, comprisingadministering to the subject an effective amount of Arg34, Lys26(Nε

  • -(γ

    -Glu(Nε

    -hexadecanoyl)))-GLP-1(7-37);

    wherein the subject is obese and has a BMI greater than 25;

    wherein the abnormal or excessive intake of food is of a first food comprising a glycemic index above 40%, wherein more than 30% of the total energy in said first food stems from fat, and a second food comprising mono- and di-saccharides that together constitute more than 50% of the total amount of carbohydrate in said second food; and

    wherein the food preference is shifted away from the first food and the second food.

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