Modular skin-adherable system for medical fluid delivery

• US 9,486,574 B2
• Filed: 10/25/2013
• Issued: 11/08/2016
• Est. Priority Date: 04/09/2008
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Inventors: Yodfat, Ofer, Dan, Yair, Arnold, Ofer, Neta, Avraham, Shalev, Yossi
• Primary Examiner(s): LANDRY II, GERALD ERNEST
• Application Number:
  US14/063,751
• Publication Number:
  US 20140052055A1
• Time in Patent Office: 1,110 Days
• Field of Search: 604131-155, 604/208
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/1402 Priming
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14268 with a reusable and a disposable component
• CPC Class Codes: A61M 2005/14573 with a replaceable reservoir for quick connection/disconnection with a driving system
• CPC Class Codes: A61M 2005/314 Flat shaped barrel forms, e.g. credit card shaped
• CPC Class Codes: A61M 2205/186 the sound being acoustically amplified, e.g. by resonance
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3365 Rotational speed
• CPC Class Codes: A61M 2205/3389 Continuous level detection A61M2205/3393 takes precedence
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence

Abstract

Disclosed is a portable therapeutic fluid dispensing device. The fluid dispensing device includes a reusable part (100) comprising a reusable part housing including at least a controller and a first portion (186) of a driving mechanism, and a disposable part (200) comprising a disposable part housing including at least a reservoir (220) to retain therapeutic fluid, an outlet port to which the therapeutic fluid is dispensed, a fluid conduit providing fluid communication between the reservoir and the outlet port, and a second portion (112) of the driving mechanism. At least a portion of the disposable part housing defines at least a portion of the reservoir. Also, the second portion of the driving mechanism is mechanically couplable to the first portion of the driving mechanism upon connection of the disposable part to the reusable part.

Claims

1. A portable therapeutic fluid dispensing device comprising:

a first housing and a second housing;

a reservoir for storing a therapeutic fluid; and

a driving mechanism comprising;

a piston;

a piston rod having a first end mechanically coupled to the piston, the piston rod being at least partially threaded; and

an engagement member configured for threaded engagement with the piston rod, the engagement member being further configured to selectively enable a controlled displacement of the piston rod within at least the reservoir via the threaded engagement, and a manual displacement of the piston rod within at least the reservoir,

wherein the engagement member is movable between a first position in which the engagement member is in threaded engagement with the piston rod, and a second position in which the engagement member is released from the threaded engagement with the piston rod to allow manual displacement of the piston rod and the engagement member comprises means for moving the engagement member from the second position to the first position upon connection of the first housing and the second housing.

2. The device according to claim 1, wherein the engagement member defines a first non-threaded opening and a second threaded opening.

3. The device according to claim 2, wherein the first non-threaded opening is adjacent the second threaded opening.

4. The device according to claim 1, further comprising a first housing and a second housing connectable to the first housing, wherein the driving mechanism comprises a first portion and a second portion mechanically coupleable to the first portion upon connection of the first housing and the second housing, the second portion of the driving mechanism comprising the piston, the piston rod, and the engagement member.

5. The device according to claim 3, wherein the engagement member is moved from the second position to the first position upon connection of the first housing and the second housing.

6. The device according to claim 1, wherein the means comprises an extension that moves the engagement member to the first position when pressed upon connection of the first housing and second housing.

7. The device according to claim 1, wherein the means is a leaf spring that moves the engagement member to the first position when pressed upon connection of the first housing and the second housing.

8. The device according to claim 3, wherein at least a portion of the second housing defines at least a portion of the reservoir.

9. The device according to claim 3, wherein the second housing includes a skin-adherable base configured to receive the first housing.

10. The device according to claim 1, further comprising one or more sensors for sensing a threshold position of the piston.

11. The device according to claim 10, wherein the one or more sensors comprises at least one energy source and at least one energy detector configured to detect energy emitted by the energy source.

12. The device according to claim 11, further comprising radiation regulator for regulating an energy received by the energy detector.

13. The device according to claim 12, wherein the radiation regulator is the piston, the piston regulates the energy received by the energy detector by blocking or unblocking the energy as it moves.

14. The device according to claim 13, wherein the piston blocks the energy received by the energy detector until the piston moves past a threshold position.

15. The device according to claim 10, further comprising alert means for alerting a user when the piston has reached the threshold position.

16. The device according to claim 15, wherein the alert means generates one or more of an visual signal, audio signal, or a vibrational signal to the user when the piston has reached the threshold position.

17. The device according to claim 10, wherein the piston is configured to generate an inductance that varies with its position, the one or more sensors include an inductance sensor for sensing the inductance of the piston.

18. The device according to claim 1, further comprising an occlusion sensor for detecting occlusion in a fluid path from the reservoir to a body of a user.

19. The device according to claim 1, further comprising a controller operatively connected to the occlusion sensor, the controller being configured to suspend the operation of the unit when an occlusion is detected by the occlusion sensor.