Masked intraocular implants and lenses

• US 9,492,272 B2
• Filed: 08/13/2010
• Issued: 11/15/2016
• Est. Priority Date: 08/13/2009
• Status: Active Grant

• Current Assignee: Healthcare Royalty Partners II LP (Toronto-Dominion Bank)
• Original Assignee: Acufocus, Inc. (Bausch Health Cos., Inc.)
• Inventors: Christie, Bruce A., Kosmynine, Alexei N.
• Primary Examiner(s): PREBILIC, PAUL B
• Application Number:
  US12/856,492
• Publication Number:
  US 20110040376A1
• Time in Patent Office: 2,286 Days
• Field of Search: 623 616- 617, 623 627- 628
• US Class Current: 1/1
• CPC Class Codes: A61F 2/15 Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61F 2/1659 having variable absorption coefficient for electromagnetic radiation, e.g. photochromic lenses
• CPC Class Codes: A61F 2002/1681 having supporting structure for lens, e.g. haptics
• CPC Class Codes: A61F 2002/1696 Having structure for blocking or reducing amount of light transmitted, e.g. glare reduction
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2240/002 Designing or making customized prostheses
• CPC Class Codes: A61F 2250/0053 differing in optical properties
• CPC Class Codes: A61F 2250/0058 Additional features; Implant or prostheses properties not otherwise provided for
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: B29D 11/00317 Production of lenses with markings or patterns
• CPC Class Codes: B29D 11/023 Implants for natural eyes
• CPC Class Codes: B29K 2033/04 Polymers of esters
• CPC Class Codes: B29K 2105/0085 Copolymers

Abstract

Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Claims

1. An intraocular device comprising:

a single, monofocal lens comprising an optically powered portion, the optically powered portion including a surface with a transition zone, the transition zone configured to reduce a thickness of the lens, measured from an anterior outer surface of the lens to a posterior outer surface of the lens, adjacent to the transition zone in a direction toward an optical axis of a recessed central region of the lens compared to a thickness of the lens, measured from the anterior outer surface of the lens to the posterior outer surface of the lens, adjacent to the transition zone in a direction toward the outer periphery of the lens; and

a mask configured to block a substantial portion of light from passing through the transition zone so as to block a substantial portion of optical aberrations that would be created by light passing through the transition zone.

2. The intraocular device of claim 1, wherein the surface with the transition zone is a posterior surface of the lens.

3. The intraocular device of claim 1, wherein the surface with the transition zone is an anterior surface of the lens.

4. The intraocular device of claim 1, wherein an inner portion of the surface with the transition zone is convex, the transition zone is concave and an outer portion of the surface is convex, wherein the transition zone is adjacent the inner portion and the outer portion.

5. The intraocular device of claim 1, wherein an inner portion and an outer portion of the surface with the transition zone have a positive optical power, and the transition zone is adjacent the inner portion and the outer portion.

6. The intraocular device of claim 1, wherein the surface with the transition zone comprises an inner portion and an outer portion, and an outer perimeter of the inner portion is surrounded by an inner perimeter of the transition zone.

7. The intraocular device of claim 6, wherein an outer perimeter of the transition zone is surrounded by an inner perimeter of the outer portion.

8. The intraocular device of claim 1, wherein the surface with the transition zone comprises an inner portion and an outer portion, and a maximum thickness of the lens in a region of the inner portion is less than the maximum thickness of the lens in a region of the transition zone.

9. The intraocular device of claim 1, wherein the mask is between the surface with the transition zone and a second surface of the lens.

10. The intraocular device of claim 1, wherein the mask comprises an aperture and an opaque region adjacent the aperture.

11. The intraocular device of claim 10, wherein the aperture comprises a diameter of about 0.85 mm to about 1.8 mm.

12. The intraocular device of claim 11, wherein the mask comprises an outer diameter of about 3 mm to about 5 mm.

13. The intraocular device of claim 1, wherein the mask increases depth of focus of a patient.

14. The intraocular device of claim 1, further comprising a haptic attached to the lens to prevent the intraocular device from moving after being implanted within an eye.

15. The intraocular device of claim 1, wherein the mask comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

16. The intraocular device of claim 1, further comprising a support member coupled to the mask and extending from the mask to an outer surface of the lens.

17. The intraocular device of claim 16, wherein the mask comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

18. The intraocular device of claim 17, wherein the support member comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

19. The intraocular device of claim 1, further comprising haptics coupled to the lens.

21. The intraocular device of claim 1, wherein the transition zone reduces the thickness of the lens between 31% and 64%.

24. The intraocular device of claim 1, wherein the mask is configured to block substantially all of the light passing through the transition zone.

25. The intraocular device of claim 1, wherein the surface with the transition zone includes an outer portion and an inner portion, and wherein the transition zone extends from the outer portion to the inner portion of the surface.

26. The intraocular device of claim 1, wherein the mask is spaced apart from the surface with the transition zone and positioned across the entire transition zone.

27. The intraocular device of claim 1, wherein the optically powered portion is configured to improve a patient'"'"'s vision when the intraocular device is implanted in an eye.

28. The intraocular device of claim 1, wherein a non-reduced thickness of the lens is between 0.26 mm and 1.40 mm.

29. The intraocular device of claim 28, wherein the transition zone is configured to reduce the thickness of the lens between 31% and 64%.

20. An intraocular device comprising:

a monofocal lens comprising a first surface and a second surface, the first surface comprising;

a first portion positioned at a central region of the first surface,

an annular second portion, and

an annular third portion positioned at an outer periphery of the first surface, the annular third portion positioned radially outward from the first portion,

wherein an optical axis of the lens passes through the first portion, and the annular second portion extends from the first portion to the annular third portion;

a mask positioned between the second surface and the annular second portion of the first surface; and

wherein the first surface comprises a single sloped portion such that the first portion is closer to the second surface than the third portion, the single sloped portion being the second portion.

22. The intraocular device of claim 20, wherein the mask comprises a plurality of holes characterized in that at least one of the hole size, shape, orientation, and spacing of the plurality of holes is varied to reduce the tendency of the holes to produce visible diffraction patterns.

23. The intraocular device of claim 20, wherein the mask comprises an aperture and an opaque region adjacent the aperture.