Shunt device and method for treating ocular disorders

• US 9,492,320 B2
• Filed: 06/26/2014
• Issued: 11/15/2016
• Est. Priority Date: 04/26/1999
• Status: Expired due to Fees

• Current Assignee: Glaukos Corporation
• Original Assignee: Glaukos Corporation
• Inventors: Lynch, Mary G., Brown, Reay H.
• Primary Examiner(s): DEAK, LESLIE R
• Application Number:
  US14/316,605
• Publication Number:
  US 20150148730A1
• Time in Patent Office: 873 Days
• Field of Search: 604/8
• US Class Current: 1/1
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61F 2230/0052 T-shaped
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 2210/0612 Eyes
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0074 Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable

Abstract

Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemm'"'"'s canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemm'"'"'s canal.

Claims

1. An ocular implant configured to maintain patency of Schlemm'"'"'s canal of an eye in a stenting fashion, the ocular implant comprising:

a body of biocompatible material of a size and shape adapted to facilitate the passage of aqueous humor into and across a trabecular meshwork of the eye;

the body having a length and shape adapted to be circumferentially retained within a portion of Schlemm'"'"'s canal,

wherein the body is curved,

wherein the body is non-tubular, and

wherein the body comprises at least one opening configured to facilitate passage of aqueous humor.

2. The ocular implant of claim 1, wherein the body comprises a curve having a radius between 3 mm and 10 mm.

3. The ocular implant of claim 1, wherein the body has a length of between 1 mm and 20 mm.

4. The ocular implant of claim 1, wherein the body has an outer cross-sectional dimension of between 0.1 mm and 0.5 mm.

5. The ocular implant of claim 1, wherein the body comprises a first elongated edge and a second elongated edge, and wherein the first elongated edge and the second elongated edge are configured to contact an internal surface of Schlemm'"'"'s canal when the ocular implant is implanted within Schlemm'"'"'s canal.

6. The ocular implant of claim 1, wherein at least a portion of the body is trough-like.

7. The ocular implant of claim 6, wherein the portion of the body which is trough-like is configured to open towards collecting channels of the eye.

8. The ocular implant of claim 1, wherein the body is non-lumenal.

9. The ocular implant of claim 1, wherein the at least one opening comprises a portal.

10. The ocular implant of claim 1, wherein the at least one opening comprises at least one fenestration.

11. An ocular implant configured to maintain patency of Schlemm'"'"'s canal in a stenting fashion, the ocular implant comprising:

a body of biocompatible material of a size and shape adapted to be circumferentially retained within a portion of Schlemm'"'"'s canal,

wherein the body is non-tubular

wherein the body is curved, and

wherein the body comprises at least one opening configured to facilitate passage of aqueous humor.

12. The ocular implant of claim 11, wherein the body comprises a curve having a radius of between 3 mm and 10 mm.

13. The ocular implant of claim 11, wherein the body has a length of between 1 mm and 20 mm.

14. The ocular implant of claim 11, wherein the body has an outer cross-sectional dimension of between 0.1 mm and 0.5 mm.

15. The ocular implant of claim 11, wherein at least a portion of the body is trough-like and non-lumenal.

16. The ocular implant of claim 15, wherein the portion of the body which is trough-like and non-lumenal is configured to open towards collecting channels of the eye.

17. The ocular implant of claim 11, wherein the body comprises a first elongated edge and a second elongated edge, and wherein the first elongated edge and the second elongated edge are configured to contact an internal surface of Schlemm'"'"'s canal when the ocular implant is implanted within Schlemm'"'"'s canal.

18. The ocular implant of claim 11, wherein the at least one opening comprises a portal.

19. The ocular implant of claim 11, wherein the at least one opening comprises at least one fenestration.

20. A shunt for implantation within an eye, the shunt comprising:

a proximal end;

a distal end; and

a non-tubular curved body disposed between the proximal end and the distal end, the curved body comprising a first edge disposed on a first side of a longitudinal axis of the curved body and a second edge disposed on a second side of a longitudinal axis of the curved body; and

a portal positioned at a location between the proximal end and the distal end along the curved body,

wherein at least the curved body is configured to be received circumferentially within a portion of Schlemm'"'"'s canal of the eye.

21. The shunt of claim 20, wherein the portal is configured to open towards the collecting channels of the eye when the shunt is implanted within Schlemm'"'"'s canal.

22. The shunt of claim 20, wherein the curved body has a pre-formed curvature to approximate a radius of Schlemm'"'"'s canal.

23. The shunt of claim 20, wherein the curved body comprises a flexible material.

24. The shunt of claim 20, wherein the portal is ovoid in shape.

25. The shunt of claim 20, wherein the curved body comprises a partially-open, trough-like channel extending from the proximal end to the distal end.

26. The ocular implant of claim 25, wherein the partially-open, trough-like channel is configured to open towards collecting channels of the eye.

27. The shunt of claim 20, wherein the outer cross-sectional dimension of the curved body is between 0.1 mm and 0.5 mm.

28. The shunt of claim 20, wherein the length of the curved body is between 1 mm and 40 mm.

29. The shunt of claim 20, wherein the portal extends through an entire thickness of the curved body.