Heat exchange catheter and their methods of manufacture and use

• US 9,492,633 B2
• Filed: 09/28/2012
• Issued: 11/15/2016
• Est. Priority Date: 09/30/2011
• Status: Expired due to Fees

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Inventors: Dabrowiak, Jeremy Thomas
• Primary Examiner(s): Bouchelle, Laura
• Assistant Examiner(s): Zamory, Justin L
• Application Number:
  US13/631,410
• Publication Number:
  US 20130090593A1
• Time in Patent Office: 1,509 Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2007/0054 with a closed fluid circuit, e.g. hot water
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/0096 with a thermometer
• CPC Class Codes: A61F 2007/0098 ways of manufacturing heating or cooling devices for therapy
• CPC Class Codes: A61F 2007/0261 medicated
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61M 2025/0183 Rapid exchange or monorail catheters
• CPC Class Codes: A61M 25/0015 Making lateral openings in a catheter tube, e.g. holes, slits, ports, piercings of guidewire ports; Methods for processing the holes, e.g. smoothing the edges
• CPC Class Codes: A61M 25/0026 Multi-lumen catheters with stationary elements catheter assemblies comprising a catheter in combination with a guide tube, sheath or sleeve A61M2025/0681; catheters comprising telescoping coaxial elements A61M2025/0175
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

A closed loop catheter useable for heat exchange is manufactured by forming a plurality of generally transverse bore holes though a flexible, multilumen catheter body, lacing a tube trough the bore holes so that loops of the tube protrude from the catheter body, connecting one end of the tube to an inflow lumen of the catheter and connecting the other end of the tube to an outflow lumen of the catheter. A heated or cooled heat exchange medium may then be circulated through the tube while the catheter is inserted in the vasculature of a subject, thereby resulting in heat exchange between the subject'"'"'s flowing blood and the heat exchange medium being circulated through the tube.

Claims

1. A method for manufacturing a catheter device, said method comprising the steps of:

A) providing or obtaining an elongate catheter body having, a proximal end, a distal end, an inflow lumen and an outflow lumen;

B) forming a plurality of bores transversely through the catheter body at spaced-apart locations;

C) passing a tube in alternate transverse directions through adjacent ones of said bores such that loops of the tube protrude outwardly from opposite sides of the catheter body;

D) connecting a first end of the tube to the inflow lumen; and

E) connecting a second end of the tube to the outflow lumen;

wherein step D comprises;

forming an opening at a first location in the catheter body and into the inflow lumen;

inserting the first end of the tube through the opening and into the inflow lumen; and

,

securing the tube to a wall of the inflow lumen.

2. A method according to claim 1 wherein the catheter body further comprises a through tube or through lumen that extends through at least a portion of the catheter body and terminates distally in a distal port.

3. A method according to claim 1 further comprising the step of forming tubing loops to desired shapes.

4. A method according to claim 3 wherein the tubing loops are formed to curved shapes.

5. A method according to claim 3 wherein the tubing loops are thermoset in desired shapes.

6. A method according to claim 1 wherein the opening is formed by skiving a window into the inflow lumen at a first location in a wall of the catheter.

7. A method according to claim 1 wherein step E comprises:

forming a second opening at a second location in the catheter body and into the outflow lumen;

inserting the second end of the tube through the second window into the outflow lumen; and

,

securing the second tube to a wall of the outflow lumen.

8. A method according to claim 7 wherein the second location is distal to the first location.

9. A method according to claim 7 wherein the second location is proximal to the first location.

10. A method according to claim 7 wherein the first location is proximal to the transverse bores and the second location is distal to the transverse bores.

11. A method according to claim 7 wherein the first location is distal to the transverse bores and the second location is proximal to the transverse bores.

12. A method according to claim 10 wherein the transverse bores are formed in a manner that obliterates adjacent portions of the inflow lumen but leaves adjacent portions of the outflow lumen intact.

13. A method according to claim 11 wherein the transverse bores are formed in a manner that obliterates adjacent portions of the outflow lumen but leaves adjacent portions of the inflow lumen intact.

14. A method according to claim 1 wherein the bores formed in Step B are oval or ovoid in shape.

15. A method according to claim 1 wherein a longitudinal axis is projectable through the catheter body and wherein the bores are formed in Step B by advancing a punch through the catheter body at an angle relative to the longitudinal axis of the catheter body.

16. A method according to claim 15 wherein the punch is advanced at substantially a right angle to the longitudinal axis of the catheter body.

17. A method according to claim 15 wherein the punch has an oval or ovoid shape which causes the bores to be oval or ovoid in shape.

18. A method according to claim 7 wherein the second opening is formed by skiving a window into the outflow lumen at a second location in a wall of the catheter.

19. A method according to claim 1 wherein Step B comprises forming said plurality of bores by a method selected from:

drilling, punching, laser cutting, blade cutting and water jet cutting.