Implantable neurostimulation systems and methods thereof

• US 9,492,660 B2
• Filed: 12/09/2014
• Issued: 11/15/2016
• Est. Priority Date: 12/09/2014
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Peichel, DeLea, Mouchawar, Gabriel A., Dulak, Gary R., Williamson, Richard, Shahandeh, Reza, Min, Xiaoyi, Sison, Shiloh, Raines, Aaron
• Primary Examiner(s): Patton, Amanda
• Assistant Examiner(s): Edwards, Philip C
• Application Number:
  US14/565,155
• Publication Number:
  US 20160158540A1
• Time in Patent Office: 707 Days
• Field of Search: 607/116
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/086 Magnetic resonance imaging [MRI] compatible leads
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

The present disclosure provides neurostimulation methods and system for deep brain stimulation. A neurostimulation system for deep brain stimulation includes a burr hole plug including a cover and a base, and at least one deep brain stimulation (DBS) lead extending through an aperture defined through the base, the at least one DBS lead including at least one DBS electrode configured to apply stimulation to a subject. The system further includes an implantable pulse generator (IPG), an extension electrically coupling the IPG to the at least one DBS lead, and an indifferent electrode positioned proximate the at least one DBS electrode to facilitate reducing an area between the indifferent electrode and the at least one DBS electrode.

Claims

1. A neurostimulation system for deep brain stimulation, the neurostimulation system comprising:

a burr hole plug comprising a cover and a base;

at least one deep brain stimulation (DBS) lead extending through an aperture defined through the base, the at least one DBS lead including at least one DBS electrode configured to apply stimulation to a subject;

an implantable pulse generator (IPG);

an extension electrically coupling the IPG to the at least one DBS lead; and

an indifferent electrode positioned proximate the at least one DBS electrode to facilitate reducing an area between the indifferent electrode and the at least one DBS electrode;

the base including a metallic bottom, the metallic bottom comprising the indifferent electrode, with the indifferent electrode being sized and shaped to facilitate preventing heating during application of radio frequency fields; and

the at least one DBS lead including an indifferent ring and the base including at least one metallic clip with the metallic clip being configured to engage the indifferent ring such that the indifferent ring is electrically coupled to the metallic bottom.

2. The neurostimulation system of claim 1, wherein the at least one metallic clip is configured to engage the indifferent ring in a snap-fit engagement.

3. The neurostimulation system of claim 1, wherein the at least one DBS lead further comprises a connector pin positioned a fixed distance from the indifferent ring.

4. The neurostimulation system of claim 1, wherein the IPG is coated with Parylene.

5. The neurostimulation system of claim 1, wherein the indifferent electrode comprises a connector pin positioned at an extension connection between the at least one DBS lead and the extension.

6. A neurostimulation system for deep brain stimulation, the neurostimulation system comprising:

a burr hole plug comprising a cover and a base;

at least one deep brain stimulation (DBS) lead extending through an aperture defined through the base, the at least one DBS lead including at least one DBS electrode configured to apply stimulation to a subject;

an implantable pulse generator (IPG);

an extension electrically coupling the IPG to the at least one DBS lead;

an indifferent electrode positioned proximate the at least one DBS electrode to facilitate reducing an area between the indifferent electrode and the at least one DBS electrode;

the base including a metallic bottom, the metallic bottom comprising the indifferent electrode, with the indifferent electrode being sized and shaped to facilitate preventing heating during application of radio frequency fields;

the at least one DBS lead including an indifferent ring and the base including at least one metallic clip with the metallic clip being configured to engage the indifferent ring such that the indifferent ring is electrically coupled to the metallic bottom, wherein the at least one metallic clip being configured to engage the indifferent ring in a snap-fit engagement; and

the indifferent electrode including a connector pin positioned at an extension connection between the at least one DBS lead and the extension.

7. The neurostimulation system of claim 6, wherein the connector pin is positioned a fixed distance from the indifferent ring.

8. The neurostimulation system of claim 6, wherein the IPG is coated with Parylene.

9. A neurostimulation system for deep brain stimulation, the neurostimulation system comprising:

a burr hole plug comprising a cover and a base;

at least one deep brain stimulation (DBS) lead extending through an aperture defined through the base, the at least one DBS lead including at least one DBS electrode configured to apply stimulation to a subject;

an implantable pulse generator (IPG);

an extension electrically coupling the IPG to the at least one DBS lead;

an indifferent electrode positioned proximate the at least one DBS electrode to facilitate reducing an area between the indifferent electrode and the at least one DBS electrode;

the base including a metallic bottom, the metallic bottom comprising the indifferent electrode, with the Indifferent electrode being sized and shaped to facilitate preventing heating during application of radio frequency fields;

the at least one DBS lead including an indifferent ring and the base including at least one metallic clip with the metallic clip being configured to engage the indifferent ring such that the indifferent ring is electrically coupled to the metallic bottom; and

the at least one DBS lead including a connector pin positioned a fixed distance from the indifferent ring and at an extension connection between the at least one DBS lead and the extension.

10. The neurostimulation system of claim 9, wherein the at least one metallic clip is configured to engage the indifferent ring in a snap-fit engagement.

11. The neurostimulation system of claim 10, wherein the IPG is coated with Parylene.