System, method, and apparatus for utilizing a pumping cassette

• US 9,494,151 B2
• Filed: 06/02/2014
• Issued: 11/15/2016
• Est. Priority Date: 07/20/1999
• Status: Expired due to Fees

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Gray, Larry B., Bryant, Robert J. Jr., Spencer, Geoffrey P.
• Primary Examiner(s): Fristoe, Jr., John K
• Assistant Examiner(s): Rost, Andrew J
• Application Number:
  US14/294,116
• Publication Number:
  US 20140260556A1
• Time in Patent Office: 897 Days
• Field of Search: 251/61.1, 251/128, 417/477.2, 417/477.1, 417/395, 417/392, 417/394, 417/476, 417/474, 277/646, 604/153
• US Class Current: 1/1
• CPC Class Codes: A61M 1/1649 with pulsatile dialysis fluid flow
• CPC Class Codes: A61M 1/267 used for pumping
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362264 the filter being a blood filter
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/367 Circuit parts not covered by the preceding subgroups of group A61M1/3621
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2209/02 Equipment for testing the apparatus
• CPC Class Codes: A61M 39/228 with a tubular diaphragm constrictable by radial fluid force
• CPC Class Codes: A61M 5/14 Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: F04B 43/067 the fluid being actuated directly by a piston
• CPC Class Codes: F04B 45/00 Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
• CPC Class Codes: F04B 45/02 having bellows
• CPC Class Codes: F04B 49/065 and making use of computers
• CPC Class Codes: F04B 49/12 : by varying the length of stroke of the working members
• CPC Class Codes: F04B 53/10 : Valves; Arrangement of valves
• CPC Class Codes: F04B 53/16 : Casings; Cylinders; Cylinder liners or heads; Fluid connections
• CPC Class Codes: G01M 3/26 : by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
• CPC Class Codes: G01M 3/32 : for containers, e.g. radiators
• CPC Class Codes: G05D 16/20 : characterised by the use of electric means

Abstract

The present invention involves, in some embodiments, fluid handling systems and methods for pumping fluid to and from a patient. The system and methods in certain embodiments involve a pumping cartridge and a reusable component configured to mate with the pumping cartridge comprising. The reusable component may comprise a control chamber and a pressure transducer configured to measure a gas pressure associated with the control chamber, and may further include a processor configured to supply the control chamber with a gas at a predetermined pressure, open the pump chamber to the surroundings, monitor the gas pressure associated with the control chamber using the pressure transducer over a predetermined period of time, and determine if the change in gas pressure exceeds a predetermined limit.

Claims

1. A method for testing a pumping cartridge when mated to a reusable component of a fluid handling system for pumping fluids to and from a patient, the reusable component comprising a control chamber, the method comprising:

pressurizing the control chamber with a gas from a source of pressurized gas before the pumping cartridge is primed with liquid;

monitoring a gas pressure associated with the control chamber over a predetermined period of time;

determining a change of the gas pressure associated with the control chamber; and

determining whether the change in the gas pressure associated with the control chamber exceeds a predetermined limit.

2. The method of claim 1, further comprising declaring a fault condition if the change in the gas pressure exceeds the predetermined limit.

3. The method of claim 2, further comprising terminating operation of the pumping cartridge if a fault condition is declared.

4. The method of claim 1, further comprising closing at least one inlet valve to the control chamber to isolate the control chamber before monitoring the gas pressure associated with the control chamber.

5. The method of claim 1, further comprising opening at least one inlet valve to the control chamber before pressurizing the control chamber.

6. The method of claim 1, further comprising isolating the control chamber before monitoring the gas pressure associated with the control chamber.

7. The method of claim 6, wherein isolating the control chamber comprises closing at least one inlet valve to the control chamber.

8. The method of claim 1, wherein monitoring the gas pressure associated with the control chamber comprises measuring the gas pressure using a pressure transducer.

9. The method of claim 1, wherein the pumping cartridge comprises a flexible membrane and a rigid portion comprising a pump chamber, the flexible membrane configured to separate the pump chamber from the control chamber, wherein the method further comprises opening the pump chamber to the surroundings before pressurizing the control chamber.

10. The method of claim 9, wherein opening the pump chamber to the surroundings comprises opening at least one valve in fluid communication with the pump chamber.

11. A fluid handling system for pumping fluids to and from a patient comprising:

a pumping cartridge comprising a pump chamber;

a reusable component configured to mate with the pumping cartridge comprising;

a control chamber in valved fluid communication with a source of pressurized gas; and

a pressure transducer configured to measure a gas pressure associated with the control chamber;

a processor configured to perform a dry pumping cartridge integrity test before any liquid is introduced into the pumping cartridge, the test comprising;

pressurizing the control chamber with a gas from the source of pressurized gas;

opening the pump chamber to the surroundings;

monitoring a gas pressure associated with the control chamber using the pressure transducer over a predetermined period of time; and

determining whether a change in the gas pressure exceeds a predetermined limit.

12. The system of claim 11, wherein the processor is configured to indicate a fault condition if the change in gas pressure associated with the control chamber exceeds the predetermined limit.

13. The system of claim 12, wherein the processor is configured to terminate operation of the pumping cartridge if the change in gas pressure associated with the control chamber exceeds the predetermined limit.

14. The system of claim 11, wherein the processor is configured to commence operation of the system if the change in gas pressure associated with the control chamber fails to exceed the predetermined limit.

15. The system of claim 11, further comprising an inlet line connected to the control chamber.

16. The system of claim 11, further comprising an occluder for blocking flow of fluid within an inlet line to the control chamber.

17. The system of claim 16, wherein the occluder is a valve.

18. The system of claim 16, wherein the occluder is located within the reusable component.

19. The system of claim 11, wherein a portion of the flexible membrane of the pumping cartridge overlying the pump chamber

is configured to mate with the control chamber of the reusable component.

20. The system of claim 11, wherein opening the pump chamber to the surroundings comprises opening at least one valve in fluid communication with the pump chamber.