Multi-layered structure and method

• US 9,498,142 B2
• Filed: 07/03/2014
• Issued: 11/22/2016
• Est. Priority Date: 07/03/2014
• Status: Active Grant

• Current Assignee: Heraeus Deutschland GmbH & Co. KG (Heraeus Holding GMBH)
• Original Assignee: Heraeus Deutschland GmbH & Co. KG (Heraeus Holding GMBH)
• Inventors: Hafiz, Jami A., Schibli, Stefan, Troetzschel, Jens
• Primary Examiner(s): Mandala, Michelle
• Assistant Examiner(s): Vuong, Thai T
• Application Number:
  US14/323,163
• Publication Number:
  US 20160005509A1
• Time in Patent Office: 873 Days
• Field of Search: 257/676, 438/674
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/125 characterised by the manufacture of electrodes
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6846 specially adapted to be brought in contact with an internal body part, i.e. invasive
• CPC Class Codes: A61B 5/6851 Guide wires
• CPC Class Codes: A61M 2025/09108 Methods for making a guide wire
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: B21F 19/00 Metallic coating of wire by extruding B21C23/24; by soldering or welding, e.g. cladding or plating B23K; by other non-mechanical means C23; electroplating C25D
• CPC Class Codes: C08G 2261/1424 containing ether groups, including alkoxy
• CPC Class Codes: C08G 2261/3223 containing one or more sulfur atoms as the only heteroatom, e.g. thiophene
• CPC Class Codes: C08G 2261/51 Charge transport
• CPC Class Codes: C08G 2261/65 Electrical insulator
• CPC Class Codes: C08G 2261/70 Post-treatment
• CPC Class Codes: C08G 2261/79 doping
• CPC Class Codes: C08G 2261/90 Applications
• CPC Class Codes: H01B 1/127 comprising five-membered aromatic rings in the main chain, e.g. polypyrroles, polythiophenes
• CPC Class Codes: H01B 1/128 comprising six-membered aromatic rings in the main chain, e.g. polyanilines, polyphenylenes
• CPC Class Codes: H01B 3/307 Other macromolecular compounds
• CPC Class Codes: H01B 7/048 for implantation into a human or animal body, e.g. pacemaker leads
• CPC Class Codes: H10K 85/1135 : Polyethylene dioxythiophene [PEDOT]; Derivatives thereof

Abstract

One aspect relates to a method for producing a layered structure, including providing a substrate, forming a first layer onto at least part of the substrate, the first layer being a first polymer, and forming a second layer onto at least part of the first layer, the second layer being a second polymer. The substrate and the second layer are electrically conductive and the first layer is insulating or the substrate and the second layer are insulating and the first layer is electrically conductive. Forming each of the first and second layers includes forming such that each layer is no more than one tenth of the thickness of the substrate.

Claims

1. A method for producing a layered structure comprising:

providing a substrate having a thickness and comprising a material that is biocompatible;

forming a first layer onto at least part of the substrate, the first layer being a first biocompatible polymer;

forming a second layer onto at least part of the first layer, the second layer being a second biocompatible polymer;

wherein the substrate and the second layer are electrically conductive and the first layer is insulating or the substrate and the second layer are insulating and the first layer is electrically conductive; and

characterized in that forming each of the first and second layers comprises forming such that each of the first and second layers is no more than one tenth of the thickness of the substrate and such that each are configured for implantation within the human body.

2. The method according to claim 1, wherein at least one of the first and second layers comprises an electrically conductive PEDOT material.

3. The method according to claim 1 characterized in that forming each of the first and second layers comprises forming such that each of the first and second layers is no more than one fiftieth of the thickness of the substrate.

4. The method according to claim 1, wherein forming of at least one of the first and second layers comprises masking ends of the layer to define contact areas that are configured for attaching an electrically conducting contact.

5. The method according to claim 1, wherein forming of at least one of the first and second layers comprises using a conductive PEDOT polymer followed by using a chemical etch to change at least portions of the layer from conductive to insulative.

6. The method according to claim 1, further comprising forming a third layer over the second layer, the third layer comprising an insulative photoresist material.

7. A method for producing a layered cylindrical structure comprising:

providing a substrate having a diameter and comprising a material that is biocompatible;

forming a first layer onto at least part of the substrate, the first layer being a first biocompatible polymer;

forming a second layer onto at least part of the first layer, the second layer being a second biocompatible polymer, such that both the first and second layers are configured for implantation within the human body;

wherein the substrate and the second layer are electrically conductive and the first layer is insulating or the substrate and the second layer are insulating and the first layer is electrically conductive; and

characterized in that forming each of the first and second layers comprises forming such that each of the first and second layers has a thickness that is no more than one tenth of the diameter of the substrate such that overall dimensions of the layered structure are substantially determined by the diameter of the substrate.

8. The method of claim 7, wherein providing the substrate comprises providing one of a wire and a needle.

9. The method according to claim 7, wherein at least one of the first and second layers comprises an electrically conductive PEDOT material.

10. The method according to claim 7 characterized in that forming each of the first and second layers comprises forming such that each of the first and second layers is no more than one fiftieth of the thickness of the substrate.

11. The method according to claim 7, wherein forming of at least one of the first and second layers comprises masking ends of the layer to define contact areas that are configured for attaching an electrically conducting contact.

12. The method according to claim 7, wherein forming of at least one of the first and second layers comprises using a conductive PEDOT polymer followed by using a chemical etch to change at least portions of the layer from conductive to insulative.

13. The method according to claim 7, further comprising forming a third layer over the second layer, the third layer comprising an insulative photoresist material.