Signal processing for continuous analyte sensor
First Claim
1. A method for processing glucose sensor data, the method comprising:
- obtaining a glucose measurement using a glucose sensor in contact with a biological fluid, wherein the glucose sensor comprises a first electrode, a second electrode, and an enzyme-containing film, the obtaining comprising;
applying a potential to the glucose sensor at a first setting,measuring a first signal from the glucose sensor at the first setting,switching the potential from the first setting to a second setting, wherein the first setting is different from the second setting,measuring a second signal from the glucose sensor at the second setting, andgenerating a glucose concentration value, using a processor coupled to a memory of a sensor electronics unit, based at least in part on the measured first signal and the measured second signal;
displaying, using a display, a first screen presenting generated glucose concentration data over a first time period;
displaying, using the display, a second screen presenting generated glucose concentration data over a second time period, wherein the second time period is different in length from the first time period;
displaying, using the display, a third screen presenting a single generated real-time glucose concentration value;
receiving an input from a user to toggle between the first screen, the second screen, and the third screen of the display;
receiving an input from the user related to mealtime information, wherein the mealtime information is displayable on the display;
receiving information from the user related to a glucose concentration target range, wherein the glucose concentration target range is represented by an upper boundary and a lower boundary, and wherein the upper boundary and the lower boundary are user configurable; and
generating an alert responsive to detection of a hyperglycemic condition or a hypoglycemic condition based at least in part on the single generated real-time glucose concentration value being outside the glucose concentration target range,wherein the sensor electronics unit is configured to modify a glucose concentration determined from the first signal by accounting for an adjustment derived from the second signal.
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Accused Products
Abstract
Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
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Citations
36 Claims
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1. A method for processing glucose sensor data, the method comprising:
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obtaining a glucose measurement using a glucose sensor in contact with a biological fluid, wherein the glucose sensor comprises a first electrode, a second electrode, and an enzyme-containing film, the obtaining comprising; applying a potential to the glucose sensor at a first setting, measuring a first signal from the glucose sensor at the first setting, switching the potential from the first setting to a second setting, wherein the first setting is different from the second setting, measuring a second signal from the glucose sensor at the second setting, and generating a glucose concentration value, using a processor coupled to a memory of a sensor electronics unit, based at least in part on the measured first signal and the measured second signal; displaying, using a display, a first screen presenting generated glucose concentration data over a first time period; displaying, using the display, a second screen presenting generated glucose concentration data over a second time period, wherein the second time period is different in length from the first time period; displaying, using the display, a third screen presenting a single generated real-time glucose concentration value; receiving an input from a user to toggle between the first screen, the second screen, and the third screen of the display; receiving an input from the user related to mealtime information, wherein the mealtime information is displayable on the display; receiving information from the user related to a glucose concentration target range, wherein the glucose concentration target range is represented by an upper boundary and a lower boundary, and wherein the upper boundary and the lower boundary are user configurable; and generating an alert responsive to detection of a hyperglycemic condition or a hypoglycemic condition based at least in part on the single generated real-time glucose concentration value being outside the glucose concentration target range, wherein the sensor electronics unit is configured to modify a glucose concentration determined from the first signal by accounting for an adjustment derived from the second signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A glucose sensor system, the system comprising:
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a glucose sensor configured to be in contact with a biological fluid to obtain a glucose measurement, wherein the glucose sensor comprises a first electrode, a second electrode, and an enzyme-containing film; sensor electronics comprising a processor for executing computer program code stored in memory to cause the processor to; apply a potential to the glucose sensor at a first setting, measure a first signal from the glucose sensor at the first setting, switch the potential from the first setting to a second setting, wherein the first setting is different from the second setting, measure a second signal from the glucose sensor at the second setting, and generate a glucose concentration value based at least in part on the first signal and the second signal; and a user interface configured to; display a first screen presenting generated glucose concentration data over a first time period, display a second screen presenting generated glucose concentration data over a second time period, wherein the second time period is different in length from the first time period, display a third screen presenting a single generated real-time glucose concentration value, allow a user to toggle between the first screen, the second screen, and the third screen, receive an input from the user related to mealtime information and display mealtime information on the user interface, receive information from the user related to a glucose concentration target range, wherein the glucose concentration target range is represented by an upper boundary and a lower boundary, wherein the upper boundary and the lower boundary are user configurable, and generate an alert responsive to detection of a hyperglycemic condition or a hypoglycemic condition, wherein the sensor electronics unit is configured to modify a glucose concentration determined from the first signal by accounting for an adjustment derived from the second signal. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. A method for processing glucose sensor data, the method comprising:
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obtaining a glucose measurement using a glucose sensor in contact with a biological fluid, wherein the glucose sensor comprises a first electrode, a second electrode, and an enzyme-containing film, the obtaining comprising; applying a potential to the glucose sensor at a first setting, measuring a first signal from the glucose sensor at the first setting, wherein the first signal is associated with glucose concentration, switching the potential from the first setting to a second setting, wherein the first setting is different from the second setting, measuring a second signal from the glucose sensor at the second setting, and generating a glucose concentration value, using a processor coupled to a memory of a sensor electronics unit, based at least in part on the measured first signal and the measured second signal; displaying, using the display, a first screen presenting generated glucose concentration data over a first time period; displaying, using the display, a second screen presenting generated glucose concentration data over a second time period, wherein the second time period is different in length from the first time period; displaying, using the display, a third screen presenting a single generated real-time glucose concentration value; receiving an input from a user to toggle between the first screen, the second screen, and the third screen of the display; receiving an input from the user related to mealtime information, wherein the mealtime information is displayable on the display; receiving information from the user related to a glucose concentration target range, wherein the glucose concentration target range is represented by an upper boundary and a lower boundary, and wherein the upper boundary and the lower boundary are user configurable; and generating an alert responsive to detection of a hyperglycemic condition or a hypoglycemic condition based at least in part on the single generated real-time glucose concentration value being outside the glucose concentration target range, wherein the sensor electronics unit is configured to process the second signal to reduce or eliminate an effect that interferes with measurement of glucose concentration. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A glucose sensor system, the system comprising:
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a glucose sensor configured to be in contact with a biological fluid to obtain a glucose measurement, wherein the glucose sensor comprises a first electrode, a second electrode, and an enzyme-containing film; sensor electronics comprising a processor for executing computer program code stored in memory to cause the processor to; apply a potential to the glucose sensor at a first setting, measure a first signal from the glucose sensor at the first setting, wherein the first signal is associated with glucose concentration, switch the potential from the first setting to a second setting, wherein the first setting is different from the second setting, measure a second signal from the glucose sensor at the second setting, and generate a glucose concentration value based at least in part on the first signal and the second signal; and a user interface configured to; display a first screen presenting generated glucose concentration data over a first time period, display a second screen presenting generated glucose concentration data over a second time period, wherein the second time period is different in length from the first time period, display a third screen presenting a single generated real-time glucose concentration value, allow a user to toggle between the first screen, the second screen, and the third screen, receive an input from the user related to mealtime information and display mealtime information on the user interface, receive information from the user related to a glucose concentration target range, wherein the glucose concentration target range is represented by an upper boundary and a lower boundary, wherein the upper boundary and the lower boundary are user configurable, and generate an alert responsive to detection of a hyperglycemic condition or a hypoglycemic condition, wherein the sensor electronics unit is configured to process the second signal to reduce or eliminate an effect that interferes with measurement of glucose concentration.
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36. A method for processing glucose sensor data, the method comprising:
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obtaining a glucose measurement using a glucose sensor in contact with a biological fluid, wherein the glucose sensor comprises a first electrode, a second electrode, and an enzyme-containing film, the obtaining comprising; applying a potential to the glucose sensor at a first setting, measuring a first signal from the glucose sensor at the first setting, switching the potential from the first setting to a second setting, wherein the first setting is different from the second setting, measuring a second signal from the glucose sensor at the second setting, and generating a glucose concentration value, using a processor coupled to a memory of a sensor electronics unit, based at least in part on the measured first signal and the measured second signal; producing a user interface displayable using a display including a first screen of the user interface presenting generated glucose concentration data over a first time period, a second screen of the user interface presenting generated glucose concentration data over a second time period, where the second time period is different in length from the first time period, and a third screen of the user interface presenting a single generated real-time glucose concentration value; toggling between the first screen, the second screen, and the third screen of the user interface when a toggle input is received; receiving information from a user related to a glucose concentration target range, wherein the glucose concentration target range is represented by an upper boundary and a lower boundary, and wherein the upper boundary and the lower boundary are user configurable; and generating an alert responsive to detection of a hyperglycemic condition or a hypoglycemic condition based at least in part on the single generated real-time glucose concentration value being outside the glucose concentration target range, wherein the sensor electronics unit is configured to modify a glucose concentration determined from the first signal by accounting for an adjustment derived from the second signal.
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Specification