Opacity consistent polymer graft for optical sensor
First Claim
1. A sensor for placement within a living animal and for measurement of an analyte in a medium within the living animal, the sensor comprising:
- a sensor housing; and
a polymer graft including indicator molecules and covering at least a portion of the sensor housing;
wherein the polymer graft is clear, and the opacity of the graft remains the same over time.
12 Assignments
0 Petitions
Accused Products
Abstract
A sensor (e.g., an optical sensor) that may be placed within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid) within the animal. The sensor may include a sensor housing and a polymer graft including indicator molecules and covering at least a portion of the sensor housing. The opacity of the polymer graft may remain substantially the same (i.e., may have little or no variation) over time. The sensor may include a photodetector, and variation in the opacity of the polymer graft does not cause a significant change in a measurement signal output by the photodetector. The polymer hydrogel may be made of polymers including acrylic acid and/or polyethylene glycol.
9 Citations
31 Claims
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1. A sensor for placement within a living animal and for measurement of an analyte in a medium within the living animal, the sensor comprising:
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a sensor housing; and a polymer graft including indicator molecules and covering at least a portion of the sensor housing; wherein the polymer graft is clear, and the opacity of the graft remains the same over time.
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2. A sensor for placement within a living animal and for measurement of an analyte in a medium within the living animal, the sensor comprising:
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a sensor housing; and a polymer graft including indicator molecules and covering at least a portion of the sensor housing, wherein the polymer graft is clear, configured to pass a percentage of light and configured such that the percentage of light passing through the polymer graft would not change by more than 50% if the sensor were placed within the living animal for at least one month. - View Dependent Claims (3, 4, 5, 6)
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7. A sensor for placement within a living animal and for measurement of an analyte in a medium within the living animal, the sensor comprising:
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a sensor housing; and a polymer graft including indicator molecules, said polymer graft covering at least a portion of the sensor housing; a light source configured to emit excitation light to the indicator molecules of the polymer graft; a photodetector configured to receive emission light from the indicator molecules of the polymer graft and output a measurement signal indicative of the amount of the received emission light, wherein the amount of the emission light received by the photodetector is indicative of the amount of the analyte in the medium within the living animal; wherein the polymer graft is clear and configured such that variation of the opacity of the polymer graft during measurement of the analye in the medium within the living animal causes a change, which is unrelated to the amount of analyte in the medium, in the measurement signal of 20% or less. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification