Drug delivery compositions and methods
First Claim
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1. A micelle comprisinga) at least one block copolymer comprising an ionically charged polymeric segment and a non-ionically charged polymeric segment, wherein said ionically charged polymeric segment is grafted with hydrophobic moieties as side chains of said ionically charged polymeric segment, wherein said ionically charged polymeric segment is cross-linked and forms the core of the micelle, and wherein said non-ionically charged polymeric segment is hydrophilic;
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Abstract
The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.
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17 Claims
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1. A micelle comprising
a) at least one block copolymer comprising an ionically charged polymeric segment and a non-ionically charged polymeric segment, wherein said ionically charged polymeric segment is grafted with hydrophobic moieties as side chains of said ionically charged polymeric segment, wherein said ionically charged polymeric segment is cross-linked and forms the core of the micelle, and wherein said non-ionically charged polymeric segment is hydrophilic; - and
b) at least one bioactive agent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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Specification