Guidewire with adjustable stiffness

• US 9,498,603 B2
• Filed: 12/11/2012
• Issued: 11/22/2016
• Est. Priority Date: 04/23/2007
• Status: Active Grant

• Current Assignee: CardioGuidance Biomedical, LLC
• Original Assignee: CardioGuidance Biomedical, LLC
• Inventors: Hinchliffe, Peter W. J., Parodi, Juan Carlos, Lupton, Henry, Mooney, Ivan, Donohue, Colin
• Primary Examiner(s): Stout, Michael C
• Application Number:
  US13/710,777
• Publication Number:
  US 20130131643A1
• Time in Patent Office: 1,442 Days
• Field of Search: 600/585, 604/510
• US Class Current: 1/1
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61M 2025/0006 which can be secured against axial movement, e.g. by using a locking cuff
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2025/09075 having a core without a coil possibly combined with a sheath
• CPC Class Codes: A61M 2025/09083 having a coil around a core
• CPC Class Codes: A61M 2025/09091 where a sheath surrounds the coil at the distal part
• CPC Class Codes: A61M 2025/09116 Design of handles or shafts or gripping surfaces thereof for manipulating guide wires
• CPC Class Codes: A61M 2025/09133 having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
• CPC Class Codes: A61M 2025/0915 having features for changing the stiffness
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils
• CPC Class Codes: A61M 25/09041 Mechanisms for insertion of guide wires
• CPC Class Codes: A61M 25/0905 extendable, e.g. mechanisms for extension
• CPC Class Codes: A61M 5/007 for contrast media

Abstract

A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.

Claims

1. A medical guidewire system having adjustable rigidity, comprising:

a first inner wire member having a closed tip, first outer diameter, and a first stiffness,

a second intermediate tube member having a longitudinally extending opening configured to receive the first inner wire member for relative sliding movement with respect to the first inner wire member, the second intermediate tube member having regions of different flexibility along its length and a stiffness different than the first stiffness of the first inner wire member,

a third outer tube member having a longitudinally extending opening configured to receive the second intermediate tube member for relative sliding movement with respect to the first inner wire member and second intermediate tube member, the third outer tube member having a stiffness greater than the first stiffness of the first inner wire member, and

a locking member configured to fix the relative longitudinal position of the first inner wire member, the second intermediate tube member, the third outer tube member with respect to each other when the first inner wire member is in one of the retracted or advanced positions relative to the third outer tube member;

wherein the first inner wire member, a second intermediate tube member and third outer tube member are each independently slidable relative to one another to change the overall diameter, stiffness, and degree of pushability in advancement of the guidewire system, without a need to exchange the system or a portion thereof, and together the members function as a unitary structure such that a proximal region of said system permits a medical device to be longitudinally advanced to a desired location in a patient, and

further wherein the third outer tube member is configured as a rail for over-the-wire catheter insertion.

2. The guidewire system of claim 1, wherein the first inner wire member comprises a wire having a solid core for at least a majority of its length.

3. The guidewire system of claim 1, wherein the third outer tube member comprises a wound wire.

4. The guidewire system of claim 1, wherein the third outer tube member comprises a hypotube.

5. The guidewire system of claim 1, wherein the second intermediate tube member is a hypotube.

6. The guidewire system of claim 1, further comprising a first handle removably attached to a proximal portion of the first inner wire member to enable removal of the second intermediate member and the third outer tube member from the guidewire system.

7. The guidewire system of claim 6, further comprising a second handle attached to a proximal end of the second intermediate member, the second handle interlocking with the third outer tube member to fix the position of the second intermediate tube member and the third outer tube member with respect to each other.

8. The guidewire system of claim 7, wherein the second handle has a mating tapered region to frictionally interlock with the third member.

9. The guidewire system of claim 1, further comprising a stop limiting relative movement of the second intermediate tube member and the third outer tube member such that a distalmost end of the second intermediate tube member cannot extend to a distalmost end of the third outer tube member.

10. The guidewire system of claim 1 wherein the third outer tube member comprises a hypotube having a series of slots formed in a sidewall to increase flexibility.

11. The guidewire system of claim 10, wherein the second intermediate tube member comprises a hypotube with a series of slots formed in a sidewall to increase flexibility.

12. The guidewire system of claim 10, wherein the space between the slots increases toward a proximal end of the hypotube.

13. The guidewire system of claim 1, wherein the longitudinally extending opening of the third outer tube member has a reduced diameter portion at a distal end portion.

14. A multi-component medical guidewire system having adjustable rigidity comprising first, second and third coaxially positioned members,

the first member having a closed tip, a first outer diameter and a first stiffness,

the second member having regions of different flexibility along its length and a stiffness different than the first stiffness of the first member, the second member further having lumen configured to receive the first member,

the third member having a lumen configured to receive the second member,

the second member being coaxially positioned between the first and third members and having a sufficient stiffness to selectively increase the stiffness of the guidewire system upon positioning within a distal portion of the third member, and

a locking member configured to fix the relative longitudinal position of the first, the second, and the third members when the first member is in one of the retracted or advanced positions relative to the third member,

wherein the first, second and third members are independently slidable relative to one another to change the overall diameter, stiffness and pushability in advancement of the guidewire system, without a need to exchange the system or a portion thereof, and together function as a unitary guidewire structure such that a proximal region of said system permits a medical device to be longitudinally advanced to a desired location in a patient, and further

wherein the third member is configured as a rail for over-the-wire catheter insertion.

15. The guidewire system of claim 14, wherein the first member interlocks with the second member to fix the axial position of the first member.