Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
First Claim
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1. A bioprinter comprising:
- a. one or more printer heads, wherein at least one printer head comprises a means for receiving and holding at least one cartridge, wherein at least one cartridge comprises a capillary tube, and wherein said capillary tube comprises a bio-ink, wherein the bio-ink comprises a solid or semi-solid composition of living cells;
b. a UV light module comprising a chamber, wherein the at least one cartridge is receivable in the chamber and the UV light module is configured to expose UV light in the chamber prior to or during extrusion of the bio-ink; and
c. a means for extruding the bio-ink of the capillary tube by the application of pressure.
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Abstract
Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink, and support material; a UV light module for optionally exposing the contents of at least one cartridge to UV light; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Also described herein are methods of using and bioprinting cartridges for such bioprinters.
131 Citations
15 Claims
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1. A bioprinter comprising:
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a. one or more printer heads, wherein at least one printer head comprises a means for receiving and holding at least one cartridge, wherein at least one cartridge comprises a capillary tube, and wherein said capillary tube comprises a bio-ink, wherein the bio-ink comprises a solid or semi-solid composition of living cells; b. a UV light module comprising a chamber, wherein the at least one cartridge is receivable in the chamber and the UV light module is configured to expose UV light in the chamber prior to or during extrusion of the bio-ink; and c. a means for extruding the bio-ink of the capillary tube by the application of pressure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification