System and method for atlas registration

• US 9,501,829 B2
• Filed: 10/26/2015
• Issued: 11/22/2016
• Est. Priority Date: 03/29/2011
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Carlton, Keith, Blum, David, Kokones, Scott
• Primary Examiner(s): Park, Soo Jin
• Application Number:
  US14/923,325
• Publication Number:
  US 20160048962A1
• Time in Patent Office: 393 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 34/25 User interfaces for surgical systems
• CPC Class Codes: A61N 1/36128 Control systems
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: F04C 2270/041 Controlled or regulated
• CPC Class Codes: G06F 18/22 Matching criteria, e.g. proximity measures
• CPC Class Codes: G06F 3/04815 Interaction with a metaphor-based environment or interaction object displayed as three-dimensional, e.g. changing the user viewpoint with respect to the environment or object
• CPC Class Codes: G06F 3/04845 for image manipulation, e.g. dragging, rotation, expansion or change of colour
• CPC Class Codes: G06T 11/003 Reconstruction from projections, e.g. tomography
• CPC Class Codes: G06T 11/60 Editing figures and text; Combining figures or text
• CPC Class Codes: G06T 15/005 General purpose rendering architectures
• CPC Class Codes: G06T 15/08 Volume rendering
• CPC Class Codes: G06T 19/00 Manipulating 3D models or images for computer graphics
• CPC Class Codes: G06T 19/003 Navigation within 3D models or images
• CPC Class Codes: G06T 2200/04 involving 3D image data
• CPC Class Codes: G06T 2200/24 involving graphical user interfaces [GUIs]
• CPC Class Codes: G06T 2207/10064 Fluorescence image
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/10088 Magnetic resonance imaging [MRI]
• CPC Class Codes: G06T 2207/10092 Diffusion tensor magnetic resonance imaging [DTI]
• CPC Class Codes: G06T 2207/30016 : Brain
• CPC Class Codes: G06T 2219/028 : Multiple view windows (top-side-front-sagittal-orthogonal)
• CPC Class Codes: G06T 3/40 : Scaling of whole images or parts thereof, e.g. expanding or contracting
• CPC Class Codes: G06T 3/4038 : Image mosaicing, e.g. composing plane images from plane sub-images
• CPC Class Codes: G06T 7/0012 : Biomedical image inspection
• CPC Class Codes: G06T 7/30 : Determination of transform parameters for the alignment of images, i.e. image registration
• CPC Class Codes: G06T 7/33 : using feature-based methods
• CPC Class Codes: G06T 7/38 : Registration of image sequences
• CPC Class Codes: G16H 20/40 : relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 30/20 : for handling medical images, e.g. DICOM, HL7 or PACS
• CPC Class Codes: G16H 30/40 : for processing medical images, e.g. editing

Abstract

A system and method for associating anatomically significant regions with regions of one or more images may include automatically modifying images of different modalities according to different correction algorithms, providing a user interface for identifying a plane within three-dimensional data, scaling atlas structures to fit an anatomical image according to identified landmarks, registering an atlas to such an image via a combination of registration algorithms, and/or registering an atlas to such an image using a feature extraction algorithm.

Claims

1. A system for associating anatomical information with image data that forms a three-dimensional space, the system comprising:

a computer processor configured to;

output a graphical user interface (GUI) in which a first two-dimensional image slice of the image data and a second two-dimensional image slice of the image data are simultaneously displayed, wherein the first and second two-dimensional image slices are orthogonal to each other;

obtain, via user interaction with the GUI, selection of three points within the three-dimensional space, two of the three points being selected in different respective ones of the first and second two-dimensional image slices, wherein a first point of the three points corresponds to an anterior commissure (AC) and a second point of the three points corresponds to a posterior commissure (PC);

record the three points in association with the image data;

selecting an alignment point along a line connecting the AC to the PC;

aligning the image data with an anatomical atlas by anisotropically scaling the image data using a first scaling factor in an anterior/posterior direction relative to the alignment point and a second scaling factor in a superior/inferior direction relative to the alignment point, wherein the first and second scaling factors are different.

2. The system of claim 1, wherein the processor is configured to align the anatomical atlas with the image data using the second scaling factor in a left/right direction relative to the alignment point.

3. The system of claim 1, wherein the GUI further includes a display of a third two-dimensional image slice that is parallel to the first two-dimensional image slice, and one of the three points is selected at a region of the second two-dimensional image slice, the region corresponding to the third two-dimensional image slice.

4. The system of claim 1, wherein the alignment point is a mid-commissural point (MCP).

5. The system of claim 1, wherein aligning the image data with an anatomical atlas by anisotropically scaling the image data further comprises aligning the image data with the anatomical atlas by non-linearly scaling the image data in at least one direction.

6. The system of claim 5, wherein aligning the image data with an anatomical atlas by anisotropically scaling the image data further comprises aligning the image data with the anatomical atlas by non-linearly scaling the image data in the anterior/posterior direction and in the superior/inferior direction.

7. The system of claim 5, wherein aligning the image data with an anatomical atlas by anisotropically scaling the image data further comprises aligning the image data with the anatomical atlas by non-linearly scaling the image data in the superior/inferior direction and linearly scaling the image date in the anterior/posterior direction.

8. The system of claim 1, wherein at least one of the first scale factor or the second scale factor varies with distance from the alignment point.

9. The system of claim 8, wherein both of the first scale factor and the second scale factor vary with distance from the alignment point.

10. The system of claim 9, wherein the first and second scale factors vary inversely with distance from the alignment point.