Neuro-behavioral test method for screening and evaluating therapy for ADHD and system
First Claim
1. A method of screening for attention deficit hyperactivity disorder (ADHD) comprising the steps of:
- a) measuring and, with a processor, analyzing EEG signals from a subject over a measurement time period;
b) measuring and, with the processor, analyzing a non-EEG response of the subject to a stimulus over the measurement time period;
c) calculating, with the processor, a neuro-behavioral index corresponding to the measured EEG signals and the measured non-EEG response; and
d) determining whether the subject has ADHD based in part on the neuro-behavioral index.
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Abstract
A new neuro-behavioral test with analysis algorithms has been developed for use in screening individuals for attention deficit hyperactivity disorder (ADHD) and for the quantitative evaluation of ADHD medication/therapy in diagnosed patients. This technique combines a 15 minute auditory-based test of attention with simultaneous EEG monitoring by a wireless, portable data acquisition device. This system acquires both behavioral response (i.e., reaction times to target stimuli, as well as errors of omission/commission) and EEG waveforms. All of the data is simultaneously processed by the algorithms to produce several representative indices. These indices are then combined to produce an overall neuro-behavioral index that represents the degree by which both “behavioral” and “EEG” attention is maintained throughout the test.
48 Citations
20 Claims
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1. A method of screening for attention deficit hyperactivity disorder (ADHD) comprising the steps of:
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a) measuring and, with a processor, analyzing EEG signals from a subject over a measurement time period; b) measuring and, with the processor, analyzing a non-EEG response of the subject to a stimulus over the measurement time period; c) calculating, with the processor, a neuro-behavioral index corresponding to the measured EEG signals and the measured non-EEG response; and d) determining whether the subject has ADHD based in part on the neuro-behavioral index. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A method of therapeutically treating a subject for attention deficit hyperactivity disorder (ADHD) comprising the steps of:
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a) quantitatively analyzing, with a processor, a subject'"'"'s brain wave signals and using the quantitative analysis in estimating or determining whether the subject has ADHD, the quantitative analysis at least in part including a step of calculating with the processor a neuro-behavioral index corresponding to at least one measured EEG signal and at least one measured non-EEG response of the subject to a stimulus; b) making a physical change to the subject or giving the subject a medication to make an improvement to the subject'"'"'s ADHD based in part on the quantitative analysis; c) quantitatively analyzing a second time the subject'"'"'s brain wave signals to estimate or determine the extent of the Improvement to the subject'"'"'s ADHD; and d) if necessary, making an additional physiological change to the subject or reducing or increasing the medication in response to Inc previous step. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14)
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15. A method of analyzing a subject for attention deficit hyperactivity disorder (ADHD) comprising the steps of:
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a) placing electrodes onto a subject'"'"'s head having a brain wave signal; b) providing a stimulus to the subject; c) measuring the subject'"'"'s non-brain wave response to the stimulus and the brain wave signal; d) analyzing the brain wave signal with a processor; e) calculating, with the processor, a neuro-behavioral index corresponding to the measured EEG signal and the measured non-brain wave response; and f) making a determination that the subject has ADHD based in part on the neuro-behavioral index. - View Dependent Claims (16, 17, 18, 19, 20)
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Specification