Methods, materials and apparatus for treating bone and other tissue

• US 9,504,508 B2
• Filed: 01/14/2015
• Issued: 11/29/2016
• Est. Priority Date: 06/17/2003
• Status: Active Grant

• Current Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Original Assignee: Depuy Synthes Products Incorporated (Johnson & Johnson)
• Inventors: Beyar, Mordechay, Globerman, Oren, Domb, Abraham, Shavit, Ronen, Wachsler-Avrahami, Hila
• Primary Examiner(s): Yang, Andrew
• Application Number:
  US14/596,575
• Publication Number:
  US 20150127058A1
• Time in Patent Office: 685 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/7095 the filler comprising unlinked macroscopic particles
• CPC Class Codes: A61B 17/8805 for introducing fluid filler into bone or extracting it A61B17/7097, A61B17/8833 take precedence
• CPC Class Codes: A61B 17/8811 characterised by the introducer tip, i.e. the part inserted into or onto the bone
• CPC Class Codes: A61B 17/8816 characterised by the conduit, e.g. tube, along which fluid flows into the body or by conduit connections
• CPC Class Codes: A61B 17/8819 characterised by the introducer proximal part, e.g. cannula handle, or by parts which are inserted inside each other, e.g. stylet and cannula A61B17/8825 takes precedence
• CPC Class Codes: A61B 17/8822 characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
• CPC Class Codes: A61B 17/8833 Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
• CPC Class Codes: A61B 17/8852 capable of being assembled or enlarged, or changing shape, inside the bone or disc
• CPC Class Codes: A61B 2017/00539 hydraulically
• CPC Class Codes: A61B 2017/00734 battery operated
• CPC Class Codes: A61L 24/06 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L24/043, A61L24/046 take precedence
• CPC Class Codes: A61L 2400/06 Flowable or injectable implant compositions
• CPC Class Codes: A61L 2430/38 for reconstruction of the spine, vertebrae or intervertebral discs
• CPC Class Codes: A61L 27/16 obtained by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: B01F 27/1143 screw-shaped, e.g. worms
• CPC Class Codes: B01F 33/86 Mixing heads comprising a driven stirrer
• CPC Class Codes: B01F 35/123 using scrapers for cleaning mixers
• CPC Class Codes: B01F 35/531 with baffles, plates or bars on the wall or the bottom
• CPC Class Codes: B01F 35/754251 reciprocating in the mixing receptacle
• CPC Class Codes: C08L 33/10 Homopolymers or copolymers of methacrylic acid esters

Abstract

A method of treating a vertebra, comprising:

• • (a) accessing an interior of a vertebra; and
  • (b) introducing a sufficient amount of artificial biocompatible material which does not set to a hardened condition in storage, into said bone, with sufficient force to move apart fractured portions of said bone.

Claims

1. A method of treating a vertebra, comprising:

(a) inserting a delivery device into an interior of a vertebra, the delivery device having a delivery tip with a closed distal end and an aperture that directs the bone cement out of a first side of the delivery device;

(b) extruding bone cement through the aperture and into the bone, wherein the extruded bone cement has a curved shape and a degree of the curvature is controlled via a difference in friction between a proximal side and a distal side of the aperture.

2. The method of claim 1, wherein the distal side of the aperture has a guided incline that extrudes the cement in the curved shape.

3. A method of treating a vertebra, comprising:

(a) inserting a delivery device into an interior of a vertebra, the delivery device having a delivery tip with a closed distal end and an aperture that directs the bone cement out of a first side of the delivery device;

(b) extruding bone cement through the aperture and into the bone, further comprising moving the delivery device axially during the extrusion of the cement.

4. The method of claim 3, wherein advancing a pusher through the delivery device toward the delivery tip extrudes the bone cement through the aperture.

5. The method of claim 4, wherein the pusher is advanced without twisting.

6. The method of claim 3, further comprising removing and replacing the delivery tip.

7. The method of claim 6, wherein the delivery tip is replaced by rotating the delivery tip relative to the delivery device.

8. The method of claim 3, wherein as a portion of the bone cement moves through the delivery tip, the portion of the bone cement has a curved shape.

9. A method of treating a vertebra, comprising:

(a) inserting a delivery device into an interior of a vertebra, the delivery device having a delivery tip with a closed distal end and an aperture that directs the bone cement out of a first side of the delivery device;

(b) extruding bone cement through the aperture and into the bone, further comprising rotating the delivery device during the extrusion of the cement.

10. The method of claim 9, wherein the delivery device is manually rotated.

11. The method of claim 9, wherein advancing a pusher through the delivery device toward the delivery tip extrudes the bone cement through the aperture.

12. The method of claim 11, wherein the pusher is advanced without twisting.

13. The method of claim 9, further comprising removing and replacing the delivery tip.

14. The method of claim 13, wherein the delivery tip is replaced by rotating the delivery tip relative to the delivery device.

15. The method of claim 9, wherein as a portion of the bone cement moves through the delivery tip, the portion of the bone cement has a curved shape.

16. A method of treating a vertebra, comprising:

(a) inserting a delivery device into an interior of a vertebra, the delivery device having a delivery tip with a closed distal end and an aperture that directs the bone cement out of a first side of the delivery device;

(b) extruding bone cement through the aperture and into the bone, further comprising coupling a vibrator to the delivery device prior to extruding the bone cement.

17. A method of treating a vertebra, comprising:

(a) inserting a delivery device into an interior of a vertebra, the delivery device having a delivery tip with a closed distal end and an aperture that directs the bone cement out of a first side of the delivery device;

(b) extruding bone cement through the aperture and into the bone, wherein the extruded bone cement is plastically deformed into a curved shape.

18. The method of claim 17, wherein the extruded bone cement maintains the curved shape until it contacts bone.