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Conversion of alpha-hydroxyalkylated residues in biomolecules using methyltransferases

  • US 9,505,797 B2
  • Filed: 11/17/2014
  • Issued: 11/29/2016
  • Est. Priority Date: 04/02/2009
  • Status: Active Grant
First Claim
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1. A modified nucleic acid comprising a -Q-LX group in place of a hydroxy group at the 5 position of a hydroxymethylcytosine or a hydroxymethyluracil residue, where X represents a functional group and/or a reporter group attached by linker L to Q, and Q is selected from the group consisting of S, Se, O, N, and C.

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