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Spectroscopic analysis of nutrient materials for use in a cell culture process

  • US 9,506,867 B2
  • Filed: 12/11/2013
  • Issued: 11/29/2016
  • Est. Priority Date: 12/11/2012
  • Status: Active Grant
First Claim
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1. A method of evaluating a nutrient material, the method comprising:

  • performing a Raman spectroscopic analysis on a sample of the nutrient material to obtain a Raman spectrum; and

    identifying a value of a quality parameter based on the Raman spectrum, the quality parameter relating to the nutrient material or to a cell culture grown using the nutrient material, wherein the quality parameter is a Day 8 pH or a Peak 5 or a Lactate Production Integral.

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