Assessing intra-cardiac activation patterns and electrical dyssynchrony
First Claim
1. A method comprising:
- receiving, with a processing unit, a torso-surface potential signal from each electrode of a plurality of electrodes distributed on a torso of a patient, wherein receiving the torso-surface potential signal from each electrode comprises;
receiving first torso-surface potential signals sensed during intrinsic conduction of the heart of the patient; and
receiving second torso-surface potential signals sensed during cardiac resynchronization therapy (CRT) pacing of the heart of the patient;
for each electrode of at least a subset of electrodes of the plurality of electrodes, calculating, with the processing unit, a torso-surface activation time based on the torso-surface potential signal sensed from the electrode, wherein calculating the torso-surface activation times comprises;
calculating first torso-surface activation times based on the first torso-surface potential signals; and
calculating second torso-surface activation times based on the second torso-surface potential signals, anddetermining, with the processing unit, an indication of a degree of electrical dyssynchrony of a heart of the patient based on the calculated torso-surface activation times, wherein the indication comprises a value that quantifies the degree of electrical dyssynchrony of the heart, and wherein determining the indication of the degree of electrical dyssynchrony of the heart of the patient based on the calculated torso-surface activation times comprises determining a change in electrical dyssynchrony between first torso-surface activation times and the second torso-surface activation times; and
presenting, by the processing unit, to a user, the indication of the degree of electrical dyssynchrony via a display, wherein presenting the indication of the degree of electrical dyssynchrony comprises presenting an indication of the change in electrical dyssynchrony.
1 Assignment
0 Petitions
Accused Products
Abstract
Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.
354 Citations
32 Claims
-
1. A method comprising:
-
receiving, with a processing unit, a torso-surface potential signal from each electrode of a plurality of electrodes distributed on a torso of a patient, wherein receiving the torso-surface potential signal from each electrode comprises; receiving first torso-surface potential signals sensed during intrinsic conduction of the heart of the patient; and receiving second torso-surface potential signals sensed during cardiac resynchronization therapy (CRT) pacing of the heart of the patient; for each electrode of at least a subset of electrodes of the plurality of electrodes, calculating, with the processing unit, a torso-surface activation time based on the torso-surface potential signal sensed from the electrode, wherein calculating the torso-surface activation times comprises; calculating first torso-surface activation times based on the first torso-surface potential signals; and calculating second torso-surface activation times based on the second torso-surface potential signals, and determining, with the processing unit, an indication of a degree of electrical dyssynchrony of a heart of the patient based on the calculated torso-surface activation times, wherein the indication comprises a value that quantifies the degree of electrical dyssynchrony of the heart, and wherein determining the indication of the degree of electrical dyssynchrony of the heart of the patient based on the calculated torso-surface activation times comprises determining a change in electrical dyssynchrony between first torso-surface activation times and the second torso-surface activation times; and presenting, by the processing unit, to a user, the indication of the degree of electrical dyssynchrony via a display, wherein presenting the indication of the degree of electrical dyssynchrony comprises presenting an indication of the change in electrical dyssynchrony. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
-
-
18. A system comprising:
-
a plurality of electrodes distributed on a torso of a patient; and a processing unit configured to receive a torso-surface potential signal from each electrode of the plurality of electrodes, calculate, for each electrode of at least a subset of electrodes of the plurality of electrodes, a torso-surface activation time based on the torso-surface potential signal sensed from the electrode, and determine an indication of a degree of electrical dyssynchrony of a heart of the patient based on the calculated torso-surface activation times, wherein the indication comprises a value that quantifies the degree of electrical dyssynchrony of the heart, wherein the torso-surface potential signal comprises first torso-surface potential signals sensed during intrinsic conduction of the heart of the patient and second torso-surface potential signals sensed during cardiac resynchronization therapy (CRT) pacing of the heart of the patient, wherein the processing unit is configured to calculate the torso-surface activation times by at least calculating first torso-surface activation times based on the first torso-surface potential signals and calculating second torso-surface activation times based on the second torso-surface potential signals, and wherein the indication of the degree of dyssynchrony comprises an indication of a change in electrical dyssynchrony between first torso-surface activation times and the second torso-surface activation times. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
-
-
31. A non-transitory computer-readable storage medium comprising instructions that, when executed, cause a processor to:
-
receive a torso-surface potential signal from each electrode of a plurality of electrodes distributed on a torso of a patient by at least; receiving first torso-surface potential signals sensed during intrinsic conduction of the heart of the patient; and receiving second torso-surface potential signals sensed during cardiac resynchronization therapy (CRT) pacing of the heart of the patient; calculate, for each electrode of at least a subset of electrodes of the plurality of electrodes, a torso-surface activation time based on the torso-surface potential signal sensed from the electrodes, wherein the instructions, when executed, cause the processor to calculate the torso-surface activation time by at least; calculating first torso-surface activation times based on the first torso-surface potential signals; and calculating second torso-surface activation times based on the second torso-surface potential signals; determine an indication of a degree of electrical dyssynchrony of a heart of the patient based on the calculated torso-surface activation times, wherein the indication comprises a value that quantifies the degree of electrical dyssynchrony of the heart wherein the instructions, when executed, cause the processor to determine the indication of the degree of electrical dyssynchrony by at least determining a change in in electrical dyssynchrony between first torso-surface activation times and the second torso-surface activation times; and present to a user, the indication of the degree of electrical dyssynchrony via a display by at least presenting an indication of the change in electrical dyssynchrony. - View Dependent Claims (32)
-
Specification