Selectable eccentric remodeling and/or ablation

• US 9,510,901 B2
• Filed: 11/07/2012
• Issued: 12/06/2016
• Est. Priority Date: 09/12/2003
• Status: Active Grant

• Current Assignee: Vessix Vascular, Inc. (Boston Scientific Corporation)
• Original Assignee: Vessix Vascular, Inc. (Boston Scientific Corporation)
• Inventors: Steinke, Tom A., Stone, Corbett W., Ross, Stephen O., Kelleher, Brian S., Michel, Raphael M., Koenig, Donald H.
• Primary Examiner(s): Peffley, Michael
• Application Number:
  US13/671,474
• Publication Number:
  US 20130066316A1
• Time in Patent Office: 1,490 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/0022 Balloons
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/0041 Removal of thrombosis
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00601 Cutting
• CPC Class Codes: A61B 2018/00654 with individual control of each of a plurality of energy emitting elements
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2090/373 using light, e.g. by using optical scanners
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/376 using X-rays, e.g. fluoroscopy
• CPC Class Codes: A61B 2090/3784 both receiver and transmitter being in the instrument or receiver being also transmitter
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: A61B 2218/007 Aspiration

Abstract

A catheter and catheter system for eccentric remodeling and/or removal of atherosclerotic material of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector near the distal end of the catheter body may measure circumferential atherosclerotic material distribution, and a power source selectively energizes the electrodes to eccentrically remodel the measured atherosclerotic material.

Claims

1. A system for remodeling tissue about a body lumen, the system comprising:

(a) an energy source;

(b) a catheter coupled to the energy source, the catheter including an expandable device comprising a plurality of electrodes sequentially positioned along a length of the expandable device in a helical pattern, wherein the expandable device is configurable between an expanded condition and an unexpanded condition, wherein when in the unexpanded condition, at least some of the plurality of electrodes are longitudinally and circumferentially offset relative to adjacent electrodes, wherein the expandable device moves from the unexpanded condition to the expanded condition upon activation of a release mechanism, wherein the system is configured to remodel a target tissue while inhibiting damage to collateral tissue; and

(c) a controller configured to selectively energize a subset of the plurality of electrodes.

2. The system of claim 1, wherein, when the expandable device is in the expanded condition, the plurality of electrodes are in the helical pattern.

3. The system of claim 2, wherein the plurality of electrodes are positioned along an elongated body.

4. The system of claim 3, wherein the elongated body includes at least one helical loop when the expandable device is in the expanded condition.

5. The system of claim 4, wherein the elongated body includes a plurality of helical loops when the expandable device is in the expanded condition.

6. The system of claim 4, wherein the elongated body is substantially straight when the expandable device is in the unexpanded condition.

7. The system of claim 3, wherein the elongated body includes a nickel and titanium alloy.

8. The system of claim 1, wherein at least some of the electrodes are separated from adjacent electrodes by an insulative material.

9. The system of claim 1, wherein the electrodes comprise bipolar or monopolar electrodes.

10. The system of claim 1, further comprising at least one temperature sensor associated with the expandable device.

11. The system of claim 1, further comprising at least one irrigation lumen associated with the expandable device.

12. The system of claim 1, wherein the expandable device is associated with a catheter proximate a distal end of the catheter.

13. A system for remodeling tissue about a body lumen, the system comprising:

(a) an energy source;

(b) a catheter coupled to the energy source, the catheter including an expandable device comprising a plurality of electrodes sequentially arranged along the expandable device and longitudinally and circumferentially spaced relative to adjacent electrodes, wherein the plurality of electrodes are arranged along an elongated body, wherein the elongated body is configurable between an unexpanded configuration in which the plurality of electrodes are axially and circumferentially offset from adjacent electrodes and an expanded configuration in which the elongated body is a helical shape, wherein the elongated body moves from the unexpanded configuration to the expanded configuration upon activation of a release mechanism, wherein the system is configured to remodel a target tissue while inhibiting damage to collateral tissue; and

(c) a controller configured to selectively energize a subset of the plurality of electrodes.

14. The system of claim 13, wherein the helical shape includes a plurality of helical coils.

15. The system of claim 14, wherein the plurality of helical coils are sequentially arranged along the expandable device.

16. The system of claim 13, wherein the elongated body is a tube including at least one irrigation lumen.

17. The system of claim 13, wherein at least some of the plurality of sequentially spaced electrodes are separated from adjacent electrodes by an insulative material.

18. A system for remodeling tissue about a body lumen, the system comprising:

(a) an energy source;

(b) a catheter coupled to the energy source, the catheter including an expandable device, comprising an elongated body associated with a distal portion of an elongated catheter, the elongated body including a plurality of electrodes sequentially positioned along the elongated body, wherein the elongated body is moveable between an expanded configuration and an un-expanded configuration, wherein, when in the expanded configuration, the elongated body is helical and includes at least one loop, wherein the elongated body moves from the un-expanded configuration to the expanded configuration upon activation of a release mechanism, and wherein, when in the un-expanded configuration, the elongated body is substantially straight and the plurality of electrodes are circumferentially spaced relative to adjacent electrodes; and

(c) a controller configured to selectively energize a subset of the plurality of electrodes.

19. The system of claim 18, wherein, when in the expanded configuration, the elongated body includes a plurality of loops.

20. The system of claim 18, wherein the elongated body is a tube including at least one irrigation lumen.

21. The system of claim 18, wherein the elongated body is at least partially formed from a nickel and titanium alloy.

22. A system for remodeling tissue about a body lumen, the system comprising:

(a) an energy source;

(b) an expandable device associated with an elongated catheter coupled to the energy source, wherein the expandable device moves from an un-expanded configuration to an expanded configuration upon activation of a release mechanism, wherein the expandable device, when in an expanded configuration, includes at least one helical loop, wherein the helical loop includes a plurality of electrodes sequentially spaced along the helical loop and circumferentially spaced relative to adjacent electrodes, and wherein, when in the un-expanded configuration, at least some of the plurality of electrodes are circumferentially offset relative to adjacent electrodes; and

(c) a controller configured to selectively energize a subset of the plurality of electrodes.