Responsive gastric stimulator

• US 9,517,152 B2
• Filed: 01/06/2015
• Issued: 12/13/2016
• Est. Priority Date: 05/01/2001
• Status: Expired due to Fees

• Current Assignee: IntraPace, Inc.
• Original Assignee: IntraPace, Inc.
• Inventors: Imran, Mir A.
• Primary Examiner(s): Alter, Alyssa M
• Application Number:
  US14/590,740
• Publication Number:
  US 20150119953A1
• Time in Patent Office: 707 Days
• Field of Search: 607/40
• US Class Current: 1/1
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61B 2017/00017 Electrical control of surgical instruments
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00477 Coupling A61B2017/0046 takes precedence
• CPC Class Codes: A61F 2005/0016 comprising measuring means
• CPC Class Codes: A61F 5/0026 Anti-eating devices using electrical stimulation
• CPC Class Codes: A61M 2025/0233 specifically adapted for attaching to a body wall by means which are on both sides of the wall, e.g. for attaching to an abdominal wall
• CPC Class Codes: A61M 2025/028 having a mainly rigid support structure
• CPC Class Codes: A61M 25/02 Holding devices, e.g. on the body
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36085 Eating disorders or obesity
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators

Abstract

A responsive gastrointestinal stimulation device is provided where one or more sensors sense data corresponding to a subject or the gastrointestinal tract of a subject and responds to sensing the data by stimulating, adjusting stimulation, or stopping stimulation of the gastrointestinal tract. A stimulation device is also provided to stimulate the gastrointestinal tract to produce a sensation of satiety or to control hunger or food consumption.

Claims

1. A method for providing obesity therapy to a patient in response to a material ingested by the patient, the method comprising:

directing emission of one or more wavelengths of light from at least one light source disposed within the patient;

receiving, in response to the emission of light, data sensed from an implantable device implanted inside the patient, the device including a transgastric probe having an intragastric optical sensor surface disposed within a cavity of a stomach of the patient so as to generate intragastric optically-sensed data;

determining a characteristic of the material ingested by the patient in response to the intragastric optically-sensed data;

transmitting signals from implanted electronic circuitry of the implantable device to external circuitry outside the patient, and outputting the ingested material characteristic from the external circuitry in response to the signals, wherein outputting the ingested material characteristic comprises communicating to a person other than the patient, and wherein the implanted electronic circuitry is disposed within the patient outside the stomach cavity and is coupled to the transgastric probe; and

wherein the outputting of the ingested material characteristic is performed so as to enhance efficacy of the obesity therapy of the patient in response to the ingested material characteristic.

2. The method of claim 1, wherein the at least one light source is an LED or optical fiber.

3. The method of claim 1, wherein the directing includes pulsing light into the stomach.

4. The method of claim 1, wherein the intragastric optical sensor senses reflected or transmitted light.

5. The method of claim 4, wherein the reflected or transmitted light indicates reflectance or absorption of wavelengths of light corresponding to the material ingested.

6. The method of claim 5, wherein the processor identifies the material ingested by the patient as being either healthy or unhealthy material based on the sensed reflected or transmitted light.

7. The method of claim 1, further comprising:

stimulating the stomach with at least one electrode implanted within the stomach of the patient.

8. The method of claim 7, wherein the stimulating causes the stomach of the patient to retain ingested material when the processor identifies the material as healthy.

9. The method of claim 7, wherein the stimulating causes the stomach of the patient to experience discomfort when the processor identifies the material as unhealthy.

10. The method of claim 1, further comprising:

marking a nutritious food with a fluorescing substance prior to ingestion of the nutritious food by the patient whereby, after ingestion of the nutritious food by the patient, the food is identified as having a characteristic wavelength of light indicative of healthy material.

11. The method of claim 1, wherein communicating to a person other than the patient provides an opportunity to monitor ingestion behavior and provide feedback to the patient.

12. The method of claim 1, further comprising:

maintaining a log of sensed data to provide a history of ingested material.

13. A device for providing obesity therapy to a patient in response to a material ingested by the patient, the device comprising:

a transgastric probe disposed within the stomach of the patient;

a intragastric optical sensor attached the probe;

at least one light source attached to the transgastric probe;

a processor coupled to the intragastric optical sensor, wherein the processor is configured to determine a characteristic of the material ingested by the patient in response to intragastric optically-sensed data; and

electronic circuitry configured to receive telemetric signals from implanted circuitry of the device and transmit the signals to external circuitry outside the patient, the signals indicative of the characteristic of the material ingested by the patient;

wherein the electronic circuitry is configured to communicate the characteristic of the material ingested by the patient to a person other than the patient and the obesity therapy so as to enhance efficacy of the obesity therapy in response to the characteristic of the material ingested by the patient.

14. The device of claim 13, wherein the intragastric optical sensor is configured to sense reflected or transmitted light, the light indicative of reflectance or absorption of wavelengths of light corresponding to ingested material.

15. The device of claim 14, wherein the processor identifies the material ingested by the patient as being either healthy or unhealthy material based on the sensed reflected or transmitted light.

16. The device of claim 13, further comprising:

at least one electrode implanted within the stomach of the patient, the electrode arranged to deliver electrically stimulating signals to the stomach in response to material ingested by the patient.

17. The device of claim 13, wherein the intragastric optical sensor includes a concave portion forming an opening to temporarily receive a sample of the material ingested by the patient.